BR112017014980A2 - método para preparação de hidrocloreto de 4-cianopiperidina. - Google Patents

método para preparação de hidrocloreto de 4-cianopiperidina.

Info

Publication number
BR112017014980A2
BR112017014980A2 BR112017014980A BR112017014980A BR112017014980A2 BR 112017014980 A2 BR112017014980 A2 BR 112017014980A2 BR 112017014980 A BR112017014980 A BR 112017014980A BR 112017014980 A BR112017014980 A BR 112017014980A BR 112017014980 A2 BR112017014980 A2 BR 112017014980A2
Authority
BR
Brazil
Prior art keywords
preparing
cyanopiperidine hydrochloride
cyanopiperidine
hydrochloride
present
Prior art date
Application number
BR112017014980A
Other languages
English (en)
Other versions
BR112017014980B1 (pt
Inventor
Brohm Dirk
Himmler Thomas
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of BR112017014980A2 publication Critical patent/BR112017014980A2/pt
Publication of BR112017014980B1 publication Critical patent/BR112017014980B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

método para preparação de hidrocloreto de 4-cianopiperidina. a presente invenção descreve a um novo método de preparação de derivados de hidrocloreto de 4-cianopiperidina.
BR112017014980-0A 2015-01-16 2016-01-13 Método para preparação de hidrocloreto de 4-cianopiperidina BR112017014980B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15151468.4 2015-01-16
EP15151468 2015-01-16
PCT/EP2016/050514 WO2016113277A1 (en) 2015-01-16 2016-01-13 Method for preparing 4-cyanopiperidine hydrochloride

Publications (2)

Publication Number Publication Date
BR112017014980A2 true BR112017014980A2 (pt) 2018-03-20
BR112017014980B1 BR112017014980B1 (pt) 2021-11-16

Family

ID=52345126

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017014980-0A BR112017014980B1 (pt) 2015-01-16 2016-01-13 Método para preparação de hidrocloreto de 4-cianopiperidina

Country Status (12)

Country Link
US (1) US10150731B2 (pt)
EP (1) EP3245190B1 (pt)
JP (1) JP6660393B2 (pt)
KR (1) KR102542097B1 (pt)
CN (1) CN107207435B (pt)
BR (1) BR112017014980B1 (pt)
DK (1) DK3245190T3 (pt)
ES (1) ES2708344T3 (pt)
IL (1) IL252920B (pt)
MX (1) MX2017009314A (pt)
TW (1) TWI693213B (pt)
WO (1) WO2016113277A1 (pt)

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH491915A (de) * 1967-06-28 1970-06-15 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
US4284636A (en) 1979-09-04 1981-08-18 Richardson-Merrell Inc. Cinnamoylpiperidinobutyrophenone antipsychotic agents
JPH01135564A (ja) * 1987-11-23 1989-05-29 Tatsumo Kk 塗布装置
US5780466A (en) 1995-01-30 1998-07-14 Sanofi Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present
US5948786A (en) * 1996-04-12 1999-09-07 Sumitomo Pharmaceuticals Company, Limited Piperidinylpyrimidine derivatives
US6248755B1 (en) * 1999-04-06 2001-06-19 Merck & Co., Inc. Pyrrolidine modulators of chemokine receptor activity
RU2301802C2 (ru) * 2003-04-15 2007-06-27 Мерк Энд Ко., Инк. Бензоксазинил-амидоциклопентил-гетероциклические модуляторы хемокиновых рецепторов
US20070238723A1 (en) * 2004-10-15 2007-10-11 Goble Stephen D Benzoxazinyl-amidocyclopentyl-heterocyclic modulators of chemokine receptors
US7348435B2 (en) 2004-10-18 2008-03-25 Jubilant Organosys Limited Process for producing cyanopiperidine
US7888374B2 (en) * 2005-01-28 2011-02-15 Abbott Laboratories Inhibitors of c-jun N-terminal kinases
US20060184921A1 (en) * 2005-02-14 2006-08-17 Appmind Software Ab Program management in hardware/software environment
US8039458B2 (en) * 2005-11-17 2011-10-18 Bristol-Myers Squibb Company HIV integrase inhibitors
WO2008013622A2 (en) * 2006-07-27 2008-01-31 E. I. Du Pont De Nemours And Company Fungicidal azocyclic amides
TW200906818A (en) 2007-07-31 2009-02-16 Astrazeneca Ab Chemical compounds
US8569337B2 (en) * 2008-07-23 2013-10-29 Vertex Pharmaceuticals Incorporated Tri-cyclic pyrazolopyridine kinase inhibitors
US20110319392A1 (en) * 2009-03-12 2011-12-29 George Adjabeng Thiazole Sulfonamide And Oxazole Sulfonamide Kinase Inhibitors
AU2010239253A1 (en) * 2009-04-23 2011-11-24 Merck Sharp & Dohme Corp. 2-alkyl piperidine mGluR5 receptor modulators
DK3141252T3 (en) * 2009-06-17 2018-11-19 Vertex Pharma INHIBITORS OF INFLUENZA VIRUS REPLICATION
CN102249949B (zh) * 2011-05-13 2013-12-18 大连奇凯医药科技有限公司 环丙基甲氰衍生物的制备方法
DK2921493T3 (da) 2011-12-27 2017-11-27 Bayer Ip Gmbh Heteroarylpiperidin og ¿piperazinderivater

Also Published As

Publication number Publication date
CN107207435B (zh) 2020-05-19
KR102542097B1 (ko) 2023-06-09
IL252920A0 (en) 2017-08-31
ES2708344T3 (es) 2019-04-09
BR112017014980B1 (pt) 2021-11-16
EP3245190A1 (en) 2017-11-22
TWI693213B (zh) 2020-05-11
CN107207435A (zh) 2017-09-26
TW201636326A (zh) 2016-10-16
DK3245190T3 (en) 2019-02-18
JP6660393B2 (ja) 2020-03-11
US10150731B2 (en) 2018-12-11
IL252920B (en) 2019-07-31
KR20170102251A (ko) 2017-09-08
JP2018503640A (ja) 2018-02-08
WO2016113277A1 (en) 2016-07-21
EP3245190B1 (en) 2018-12-26
US20170369442A1 (en) 2017-12-28
MX2017009314A (es) 2017-11-08

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Legal Events

Date Code Title Description
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 13/01/2016, OBSERVADAS AS CONDICOES LEGAIS.