BR112017011226A2 - peptídeo, composição farmacêutica, processo para fabricação da composição farmacêutica - Google Patents
peptídeo, composição farmacêutica, processo para fabricação da composição farmacêuticaInfo
- Publication number
- BR112017011226A2 BR112017011226A2 BR112017011226-4A BR112017011226A BR112017011226A2 BR 112017011226 A2 BR112017011226 A2 BR 112017011226A2 BR 112017011226 A BR112017011226 A BR 112017011226A BR 112017011226 A2 BR112017011226 A2 BR 112017011226A2
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- peptide
- manufacturing process
- composition manufacturing
- alzheimer
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01007—Acetylcholinesterase (3.1.1.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Reciprocating, Oscillating Or Vibrating Motors (AREA)
Abstract
a invenção refere-se a peptídeos, composições, terapias e métodos para o tratamento de distúrbios degenerativos, por exemplo, doença de alzheimer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1420986.0 | 2014-11-26 | ||
GB1420986.0A GB2539161A (en) | 2014-11-26 | 2014-11-26 | Neurodegenerative disorders |
PCT/GB2015/053601 WO2016083809A1 (en) | 2014-11-26 | 2015-11-26 | Neurodegenerative disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017011226A2 true BR112017011226A2 (pt) | 2018-03-27 |
Family
ID=52292544
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017011226-4A BR112017011226A2 (pt) | 2014-11-26 | 2015-11-26 | peptídeo, composição farmacêutica, processo para fabricação da composição farmacêutica |
Country Status (13)
Country | Link |
---|---|
US (1) | US10729749B2 (pt) |
EP (2) | EP4116415A1 (pt) |
JP (1) | JP6708646B2 (pt) |
KR (1) | KR102489620B1 (pt) |
CN (2) | CN107001419B (pt) |
AU (1) | AU2015352182B2 (pt) |
BR (1) | BR112017011226A2 (pt) |
CA (1) | CA2968933A1 (pt) |
ES (1) | ES2925550T3 (pt) |
GB (1) | GB2539161A (pt) |
MX (1) | MX2017006692A (pt) |
RU (1) | RU2707191C2 (pt) |
WO (1) | WO2016083809A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019229771A2 (en) * | 2018-06-01 | 2019-12-05 | Council Of Scientific And Industrial Research | Nonapeptide of formula i, pharmaceutical compositions and methods for preparation thereof |
BR112023012422A2 (pt) | 2021-01-24 | 2023-12-12 | Michael David Forrest | Inibidores da atp sintase - usos cosmético e terapêutico |
CN113698454B (zh) * | 2021-09-01 | 2022-05-24 | 北京林业大学 | 一种核桃粕乙酰胆碱酯酶抑制肽及其制备方法与应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9606040D0 (en) * | 1996-03-22 | 1996-05-22 | Isis Innovation | Active peptide |
IL131707A0 (en) * | 1999-05-31 | 2001-03-19 | Yissum Res Dev Co | Acetylcholinesterase-derived peptides and uses thereof |
GB9930825D0 (en) * | 1999-12-30 | 2000-02-16 | Synaptica Limited | Animal models for neurodegenerative disease |
AU4432901A (en) * | 2000-03-29 | 2001-10-08 | Synaptica Limited | Alpha 7 nicotinic receptor screening assays |
GB0028578D0 (en) * | 2000-11-23 | 2001-01-10 | Synaptica Ltd | Screening assays |
US20090169520A1 (en) * | 2004-01-09 | 2009-07-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compounds, Pharmaceutical Compositions and Therapeutic Methods of Preventing and Treating Diseases and Disorders Associated With Amyloid Fibril Formation |
WO2007049281A1 (en) * | 2005-10-26 | 2007-05-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Ache polypeptides, polynucleotides encoding same and compositions and methods of using same |
EP1857463A1 (en) * | 2006-05-03 | 2007-11-21 | Ebewe Pharma Ges.m.b.H. Nfg. KG | Peptide having neuroprotective effects |
GB0708646D0 (en) * | 2007-05-04 | 2007-06-13 | Enkephala Ltd | Biologically active C-terminal fragment of acetylcholinesterase |
SG10201604530SA (en) * | 2008-01-22 | 2016-07-28 | Araim Pharmaceuticals Inc | Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage |
JP5957469B2 (ja) * | 2011-02-16 | 2016-07-27 | ノバルティス アーゲー | 神経変性疾患の処置において使用するための治療剤の組み合わせ |
CN102921000B (zh) * | 2011-08-08 | 2015-02-18 | 中国科学院上海生命科学研究院 | 乙酰胆碱酯酶作为核酸酶的应用 |
AU2013240271A1 (en) * | 2012-03-26 | 2014-10-02 | Axcella Health Inc. | Nutritive fragments, proteins and methods |
GB2516045A (en) * | 2013-07-09 | 2015-01-14 | Neuro Bio Ltd | Neurodegenerative disorders |
GB201505239D0 (en) * | 2015-03-27 | 2015-05-13 | Neuro Bio Ltd | Antibody |
-
2014
- 2014-11-26 GB GB1420986.0A patent/GB2539161A/en not_active Withdrawn
-
2015
- 2015-11-26 BR BR112017011226-4A patent/BR112017011226A2/pt not_active Application Discontinuation
- 2015-11-26 MX MX2017006692A patent/MX2017006692A/es unknown
- 2015-11-26 EP EP22176401.2A patent/EP4116415A1/en active Pending
- 2015-11-26 EP EP15807974.9A patent/EP3224270B1/en active Active
- 2015-11-26 AU AU2015352182A patent/AU2015352182B2/en active Active
- 2015-11-26 ES ES15807974T patent/ES2925550T3/es active Active
- 2015-11-26 KR KR1020177017527A patent/KR102489620B1/ko active IP Right Grant
- 2015-11-26 CN CN201580064081.4A patent/CN107001419B/zh active Active
- 2015-11-26 CA CA2968933A patent/CA2968933A1/en active Pending
- 2015-11-26 US US15/529,468 patent/US10729749B2/en active Active
- 2015-11-26 WO PCT/GB2015/053601 patent/WO2016083809A1/en active Application Filing
- 2015-11-26 CN CN202210116844.7A patent/CN114410606A/zh active Pending
- 2015-11-26 RU RU2017121836A patent/RU2707191C2/ru active
- 2015-11-26 JP JP2017528104A patent/JP6708646B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
JP6708646B2 (ja) | 2020-06-10 |
WO2016083809A1 (en) | 2016-06-02 |
GB2539161A (en) | 2016-12-14 |
MX2017006692A (es) | 2017-08-21 |
RU2017121836A (ru) | 2018-12-26 |
KR102489620B1 (ko) | 2023-01-16 |
JP2018506506A (ja) | 2018-03-08 |
GB201420986D0 (en) | 2015-01-07 |
CN107001419B (zh) | 2022-02-25 |
CA2968933A1 (en) | 2016-06-02 |
EP3224270A1 (en) | 2017-10-04 |
CN114410606A (zh) | 2022-04-29 |
EP4116415A1 (en) | 2023-01-11 |
RU2707191C2 (ru) | 2019-11-25 |
AU2015352182B2 (en) | 2020-06-11 |
ES2925550T3 (es) | 2022-10-18 |
KR20170104457A (ko) | 2017-09-15 |
EP3224270B1 (en) | 2022-06-08 |
AU2015352182A1 (en) | 2017-06-29 |
US20170266265A1 (en) | 2017-09-21 |
US10729749B2 (en) | 2020-08-04 |
CN107001419A (zh) | 2017-08-01 |
RU2017121836A3 (pt) | 2019-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] |