SG10201604530SA - Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage - Google Patents

Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage

Info

Publication number
SG10201604530SA
SG10201604530SA SG10201604530SA SG10201604530SA SG10201604530SA SG 10201604530S A SG10201604530S A SG 10201604530SA SG 10201604530S A SG10201604530S A SG 10201604530SA SG 10201604530S A SG10201604530S A SG 10201604530SA SG 10201604530S A SG10201604530S A SG 10201604530SA
Authority
SG
Singapore
Prior art keywords
tissue
preventing
disorders associated
treating diseases
peptide analogs
Prior art date
Application number
SG10201604530SA
Inventor
Anthony Cerami
Michael Brines
Original Assignee
Araim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Araim Pharmaceuticals Inc filed Critical Araim Pharmaceuticals Inc
Publication of SG10201604530SA publication Critical patent/SG10201604530SA/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Reproductive Health (AREA)
SG10201604530SA 2008-01-22 2009-01-22 Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage SG10201604530SA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6201208P 2008-01-22 2008-01-22
US6202208P 2008-01-22 2008-01-22
US6204508P 2008-01-22 2008-01-22
US13391208P 2008-07-03 2008-07-03
US20389008P 2008-12-30 2008-12-30

Publications (1)

Publication Number Publication Date
SG10201604530SA true SG10201604530SA (en) 2016-07-28

Family

ID=40810017

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10202011946PA SG10202011946PA (en) 2008-01-22 2009-01-22 Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
SG10201604530SA SG10201604530SA (en) 2008-01-22 2009-01-22 Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
SG2013011762A SG188161A1 (en) 2008-01-22 2009-01-22 Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10202011946PA SG10202011946PA (en) 2008-01-22 2009-01-22 Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2013011762A SG188161A1 (en) 2008-01-22 2009-01-22 Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage

Country Status (15)

Country Link
US (4) US8853358B2 (en)
EP (2) EP2933264A3 (en)
JP (5) JP5542064B2 (en)
KR (7) KR101768792B1 (en)
CN (4) CN111346213A (en)
AU (1) AU2009206748B2 (en)
CA (1) CA2712757A1 (en)
ES (1) ES2539124T3 (en)
HK (2) HK1143822A1 (en)
IL (1) IL207155A (en)
MX (3) MX2010008050A (en)
NZ (3) NZ587105A (en)
PL (1) PL2245056T4 (en)
SG (3) SG10202011946PA (en)
WO (1) WO2009094172A2 (en)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9585932B2 (en) 2005-04-29 2017-03-07 Peter C. Dowling Use of EPO-derived peptide fragments for the treatment of neurodegenerative disorders
US9345745B2 (en) * 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
US8653028B2 (en) 2005-04-29 2014-02-18 Rui Rong Yuan Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
CA3079319A1 (en) 2005-08-05 2007-02-15 Araim Pharmaceuticals, Inc. Tissue protective peptides and uses thereof
SG10202011946PA (en) 2008-01-22 2020-12-30 Araim Pharmaceuticals Inc Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
WO2011127144A1 (en) 2010-04-06 2011-10-13 Synedgen Inc. Methods and compositions for treating wounds utilizing chitosan compounds
US9999702B2 (en) * 2010-04-09 2018-06-19 Kci Licensing Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
WO2012069474A2 (en) 2010-11-24 2012-05-31 H. Lundbeck A/S A method for reducing potential virus burden in a sample by cyanate treatment
US20130288373A1 (en) * 2010-12-20 2013-10-31 Kenneth Verstraete Crystal structure of flt3 ligand-receptor complex
WO2012174028A2 (en) * 2011-06-13 2012-12-20 The Board Of Trustees Of The University Of Illinois Peptide compositions and methods for treating lung injury, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion
FR2978964B1 (en) * 2011-08-09 2015-02-20 Conservatoire Nat Arts ANTI-IL-6 VACCINE COMPOSITION
CN105012313B (en) * 2014-04-25 2018-03-16 广州市赛普特医药科技股份有限公司 The application of the β of 5 α androstanes 3,5,6 β triols and the like in preventing or treating altitude sickness caused by hypobaric hypoxia
JP6426001B2 (en) * 2011-11-17 2018-11-21 グリア エスピー ゼット．オー．オー． Compositions and methods for treating glioma
EP2897622B1 (en) 2012-09-20 2021-04-21 Synedgen, Inc. Methods for treatment or prevention of damage resulting from radiation
US9895399B2 (en) 2013-01-31 2018-02-20 The Trustees Of The University Of Pennsylvania Repair of peripheral nerve injury
US20160222084A1 (en) 2013-03-15 2016-08-04 The Board Of Regents Of The University Of Oklahoma Compositions Comprising D-Amino Acid Peptides and Methods of Production and Use Thereof for Inhibiting Autoantibodies
SG11201600294QA (en) * 2013-07-17 2016-02-26 Araim Pharmaceuticals Inc Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
KR101510743B1 (en) * 2013-07-23 2015-04-10 (주)케어젠 Peptides Having an Inhibitory Activity on Osteoclast Differentiation and Uses Thereof
PT3104939T (en) 2014-02-10 2024-07-17 Fred Hutchinson Cancer Center Halogen treatment of heart attack and ischemic injury
US9314457B2 (en) 2014-06-19 2016-04-19 The University Of Utah Research Foundation Methods of treating and preventing vascular instability diseases
GB2539161A (en) * 2014-11-26 2016-12-14 Neuro-Bio Ltd Neurodegenerative disorders
US20180292390A1 (en) * 2015-04-23 2018-10-11 Rowan University Novel slice cultures and methods for diagnosing neuronal degeneration diseases
CN105233256A (en) * 2015-10-28 2016-01-13 中国人民解放军第三军医大学 Application of erythropoietin and erythropoietin derivatives to preparation of medicine for promoting apoptotic cell clearance during disease treatment
RU2613308C1 (en) * 2015-11-23 2017-03-15 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Method for prediction of predisposition to postoperative bleeding in case of pancreas head cancer
JP7235509B2 (en) 2016-04-14 2023-03-08 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア Implantable living electrode and method of making same
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
EP3448415A4 (en) * 2016-04-29 2019-11-06 Araim Pharmaceuticals, Inc. Tissue protective peptides for preventing and treating diseases and disorders associated with tissue damage
CN106075392B (en) * 2016-07-18 2020-07-07 滨州医学院 Application of erythropoietin derivative in hearing protection
IL247369B (en) * 2016-08-18 2018-08-30 B G Negev Tech And Applications Ltd Modified m-csf polypeptides and use thereof
US11390654B2 (en) * 2016-09-02 2022-07-19 Christopher Joseph Soares Use of CGRP receptor antagonists in neuroprotection and neurological disorders
BR112019009246B1 (en) 2016-11-10 2023-01-17 Asc Regenity Ltd COSMETIC FORMULATIONS CONTAINING MOLECULES DERIVED FROM ERYTHROPOIETIN, ISOLATED POLYPEPTIDE AND USE THEREOF
CN110475786A (en) * 2017-02-27 2019-11-19 大邱庆北科学技术院 Erythropoietin(EPO) derived peptide passes through its purposes to the effect of prevention cellular damage
JP6450999B2 (en) * 2017-03-31 2019-01-16 国立大学法人群馬大学 Treatment of Raynaud's phenomenon with botulinum toxin type B
WO2018204847A2 (en) * 2017-05-05 2018-11-08 Trefoil Therapeutics, Inc. Recombinant modified fibroblast growth factors and therapeutic uses thereof
CN110590919B (en) * 2017-05-24 2022-05-24 中国海洋大学 Short peptide containing ornithine and application thereof
EP3668532A4 (en) * 2017-08-19 2021-09-01 Ohio State Innovation Foundation Novel peptide-based cancer imaging agents
US20200223894A1 (en) * 2017-09-19 2020-07-16 Auckland Uniservices Limited Peptides for the treatment of conditions associated with adiponectin dysfunction
CN107880109B (en) * 2017-11-01 2019-08-30 复旦大学附属中山医院 A kind of hematopoietin source peptide and its preparation method and application
US10975124B2 (en) 2018-02-23 2021-04-13 The Board Of Regents Of The University Of Oklahoma Methods and compositions for treating diseases and conditions associated with gonadotropin releasing hormone receptor
KR102167641B1 (en) * 2018-08-27 2020-10-19 주식회사 사이루스 Composition for growth-promoting cell containing erythropoietin-derived peptide
CA3112382A1 (en) 2018-09-10 2020-03-19 Cold Spring Harbor Laboratory Methods for treating pancreatitis
KR20200080179A (en) * 2018-12-26 2020-07-06 아미코젠주식회사 Peptide for inhibition of acetylcholine receptor and use thereof
WO2021137932A1 (en) * 2019-11-04 2021-07-08 Faraday Pharmaceuticals, Inc. Use of iodide compounds for the treatment and prevention of chemotherapy-associated cachexia and cardiotoxicity
EP4100692A4 (en) 2020-02-06 2024-03-06 Austin Star Detonator Company Integrated detonator sensors
WO2021245677A1 (en) * 2020-06-05 2021-12-09 Digestix Bioscience Inc. Compositions and methods for treating dysplastic and early-stage neoplastic conditions
CN111863118B (en) * 2020-07-20 2023-09-05 湖南莱博赛医用机器人有限公司 TCT and DNA ploidy analysis method based on TCT flaking
CN112557347B (en) * 2020-11-12 2023-10-24 渤海大学 Preparation and detection method of chyle particle migration model in mucus layer
WO2023000038A1 (en) * 2021-07-23 2023-01-26 Lateral IP Pty Ltd Peptide compositions capable of binding lanthionine synthetase c-like protein (lancl) and uses thereof
CN114606317B (en) * 2022-03-22 2022-12-02 中山大学附属第一医院 Flora marker for predicting lymph node metastasis of gastric cancer and application thereof
CN117106057A (en) * 2022-08-19 2023-11-24 南京汉欣医药科技有限公司 High-purity human adrenocorticotropic hormone or analogue thereof and large-scale preparation method thereof

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1479268A (en) 1973-07-05 1977-07-13 Beecham Group Ltd Pharmaceutical compositions
CH596313A5 (en) 1975-05-30 1978-03-15 Battelle Memorial Institute
NO812612L (en) 1980-08-06 1982-02-08 Ferring Pharma Ltd ENZYME inhibitor.
US4414147A (en) 1981-04-17 1983-11-08 Massachusetts Institute Of Technology Methods of decreasing the hydrophobicity of fibroblast and other interferons
US4558006A (en) 1983-02-04 1985-12-10 Kirin-Amgen, Inc. A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
US5051448A (en) 1984-07-24 1991-09-24 The Mclean Hospital Corporation GABA esters and GABA analog esters
US4704355A (en) 1985-03-27 1987-11-03 New Horizons Diagnostics Corporation Assay utilizing ATP encapsulated within liposome particles
EP0229108B1 (en) 1985-06-26 1990-12-27 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
US4798824A (en) 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
US6932968B1 (en) 1989-07-26 2005-08-23 Dade Behring Marburg Gmbh Erythropoietin (EPO) peptides and antibodies directed against these
DE3924746A1 (en) * 1989-07-26 1991-01-31 Behringwerke Ag ERTHROPOIETIN (EPO) PEPTIDES AND ANTIBODIES THEREFOR
AU6501390A (en) 1989-09-21 1991-04-18 Synergen, Inc. Method for transporting compositions across the blood brain barrier
US5192746A (en) 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
WO1994005332A2 (en) 1992-09-01 1994-03-17 Berlex Laboratories, Inc. Glycolation of glycosylated macromolecules
US5559103A (en) 1993-07-21 1996-09-24 Cytel Corporation Bivalent sialyl X saccharides
US5571787A (en) 1993-07-30 1996-11-05 Myelos Corporation Prosaposin as a neurotrophic factor
US5700909A (en) 1993-07-30 1997-12-23 The Regents Of The University Of California Prosaposin and cytokine-derived peptides
WO1995021919A2 (en) 1994-02-14 1995-08-17 Kirin Brewery Company, Limited Protein having tpo activity
US5576423A (en) 1994-12-02 1996-11-19 Schering Corporation Antibodies to the slam protein expressed on activated T cells
US6849602B1 (en) 1996-03-05 2005-02-01 The Regents Of The University Of California Compositions for alleviating neuropathic pain with prosaposin receptor agonists
US6271196B1 (en) 1996-03-05 2001-08-07 Regents Of The University Of Ca Methods of alleviating neuropathic pain using prosaposin-derived peptides
US6346390B1 (en) 1996-03-08 2002-02-12 Receptron, Inc. Receptor derived peptides involved in modulation of response to ligand binding
US5952293A (en) 1996-03-08 1999-09-14 Receptron Receptor derived peptides involved in inhibition of receptor internalization in response to ligand binding
US5835382A (en) 1996-04-26 1998-11-10 The Scripps Research Institute Small molecule mimetics of erythropoietin
US6437216B1 (en) 1997-11-13 2002-08-20 Interleukin Genetics Inc. Transgenic models of inflammatory disease
IL124015A0 (en) 1998-04-08 1999-01-26 Yeda Res & Dev Pharmaceutical compositions comprising a protein
US6307024B1 (en) * 1999-03-09 2001-10-23 Zymogenetics, Inc. Cytokine zalpha11 Ligand
NZ533098A (en) 1999-04-13 2006-04-28 Kenneth S Modulation of excitable tissue function by peripherally administered erythropoietin at high doses
AU2001252650A1 (en) 2000-04-28 2001-11-12 Effector Cell Institute Novel derivative of cell chemotactic factor
US7259146B2 (en) 2000-05-26 2007-08-21 Ortho-Mcneil Pharmaceutical, Inc. Neuroprotective peptides
AU7490401A (en) * 2000-05-26 2001-12-11 Ortho Mcneil Pharm Inc Neuroprotective peptides
WO2002043572A2 (en) 2000-11-30 2002-06-06 Henry M. Jackson Foundation Erythropoietin and erythropoietin receptor expression in human cancer
PA8536201A1 (en) 2000-12-29 2002-08-29 Kenneth S Warren Inst Inc PROTECTION AND IMPROVEMENT OF CELLS, FABRICS AND ORGANS RESPONDING TO Erythropoietin
US20030072737A1 (en) 2000-12-29 2003-04-17 Michael Brines Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
US7205275B2 (en) 2001-10-11 2007-04-17 Amgen Inc. Methods of treatment using specific binding agents of human angiopoietin-2
CA2490411A1 (en) 2002-06-28 2004-01-08 Centocor, Inc. Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses
EP1552298A4 (en) 2002-07-01 2006-11-08 Kenneth S Warren Inst Inc Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
US7037902B2 (en) 2002-07-03 2006-05-02 Receptron, Inc. Affinity small molecules for the EPO receptor
EP1545586A4 (en) 2002-09-09 2007-09-26 Warren Pharmaceuticals Inc Long acting erythropoietins that maintain tissue protective activity of endogenous erythropoietin
JP2004305006A (en) 2003-04-01 2004-11-04 Japan Science & Technology Agency Artificially prepared lung surfactant
US7718363B2 (en) 2003-04-25 2010-05-18 The Kenneth S. Warren Institute, Inc. Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds
CA2525568C (en) 2003-05-12 2017-07-25 Affymax, Inc. Novel peptides that bind to the erythropoietin receptor
JP2007512001A (en) 2003-08-28 2007-05-17 バイオレクシス ファーマシューティカル コーポレイション EPO mimetic peptides and fusion proteins
BRPI0409650A (en) 2003-09-09 2006-04-25 Warren Pharmaceuticals Inc methods for regulating hematocrit and human levels, artificial erythropoietin products, methods for preparing an erythropoietin product and for treating anemia in patients at risk of tissue damage, and, pharmaceutical composition
EP1670492A4 (en) 2003-09-29 2009-07-08 Warren Pharmaceuticals Inc Tissue protective cytokines for the treatment and prevention of sepsis and the formation of adhesions
US20050090551A1 (en) 2003-10-27 2005-04-28 Board Of Trustees Of Southern Illinois University Therapeutic use of methionine for the treatment or prevention of mucositis
ME02251B (en) 2004-02-02 2015-12-31 Engeneic Molecular Delivery Pty Ltd Compositions and methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
US20080227696A1 (en) * 2005-02-22 2008-09-18 Biosurface Engineering Technologies, Inc. Single branch heparin-binding growth factor analogs
EP1740530B8 (en) 2004-03-16 2017-03-01 Temple University - Of The Commonwealth System of Higher Education Substituted phenoxy- and phenylthio-derivatives for treating proliferative disorders
US20050267027A1 (en) 2004-04-05 2005-12-01 Lounsbury Karen M Use of erythropoietin for treatment of cancer
WO2007010552A2 (en) 2005-03-17 2007-01-25 Serum Institute Of India Limited N- terminal peg conjugate of erythropoietin
US8653028B2 (en) 2005-04-29 2014-02-18 Rui Rong Yuan Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
US9345745B2 (en) 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
EP2377884A1 (en) 2005-05-10 2011-10-19 Neoloch Aps Neuritogenic peptides
EP1736481A1 (en) 2005-05-13 2006-12-27 Charite Universitätsmedizin-Berlin Erythropoietin variants
EP1888098A2 (en) 2005-05-25 2008-02-20 Neose Technologies, Inc. Glycopegylated erythropoietin formulations
CA3079319A1 (en) 2005-08-05 2007-02-15 Araim Pharmaceuticals, Inc. Tissue protective peptides and uses thereof
WO2007071248A2 (en) 2005-12-20 2007-06-28 Copenhagen University Neuritogenic and neuronal survival promoting peptides derived from the family of s-100 proteins
JP2010513309A (en) 2006-12-18 2010-04-30 アルタス ファーマシューティカルズ インコーポレイテッド Human growth hormone preparation
SG10202011946PA (en) 2008-01-22 2020-12-30 Araim Pharmaceuticals Inc Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage

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