BR112017009633A2 - métodos de tratamento de um paciente com um câncer, para identificar um paciente, para predizer a capacidade de resposta de um paciente, antagonista de vegf para utilização em um método de tratamento de um paciente com um câncer e agente terapêutico - Google Patents

métodos de tratamento de um paciente com um câncer, para identificar um paciente, para predizer a capacidade de resposta de um paciente, antagonista de vegf para utilização em um método de tratamento de um paciente com um câncer e agente terapêutico

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Publication number
BR112017009633A2
BR112017009633A2 BR112017009633A BR112017009633A BR112017009633A2 BR 112017009633 A2 BR112017009633 A2 BR 112017009633A2 BR 112017009633 A BR112017009633 A BR 112017009633A BR 112017009633 A BR112017009633 A BR 112017009633A BR 112017009633 A2 BR112017009633 A2 BR 112017009633A2
Authority
BR
Brazil
Prior art keywords
patient
cancer
treating
vegf antagonist
responsiveness
Prior art date
Application number
BR112017009633A
Other languages
English (en)
Portuguese (pt)
Inventor
Bais Carlos
C Consalvo Nicola
Choi Younjeong
Xiao Yuanyuan
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112017009633A2 publication Critical patent/BR112017009633A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
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    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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BR112017009633A 2014-11-14 2015-11-09 métodos de tratamento de um paciente com um câncer, para identificar um paciente, para predizer a capacidade de resposta de um paciente, antagonista de vegf para utilização em um método de tratamento de um paciente com um câncer e agente terapêutico BR112017009633A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462079787P 2014-11-14 2014-11-14
PCT/US2015/059733 WO2016077227A2 (en) 2014-11-14 2015-11-09 Predicting response to a vegf antagonist

Publications (1)

Publication Number Publication Date
BR112017009633A2 true BR112017009633A2 (pt) 2017-12-19

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BR112017009633A BR112017009633A2 (pt) 2014-11-14 2015-11-09 métodos de tratamento de um paciente com um câncer, para identificar um paciente, para predizer a capacidade de resposta de um paciente, antagonista de vegf para utilização em um método de tratamento de um paciente com um câncer e agente terapêutico

Country Status (15)

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US (1) US20170226198A1 (enExample)
EP (1) EP3218401B1 (enExample)
JP (1) JP2017535548A (enExample)
KR (1) KR20170082537A (enExample)
CN (1) CN107106688A (enExample)
AR (1) AR102647A1 (enExample)
AU (1) AU2015346652A1 (enExample)
BR (1) BR112017009633A2 (enExample)
CA (1) CA2966216A1 (enExample)
HK (1) HK1242996A1 (enExample)
IL (1) IL251947A0 (enExample)
MX (1) MX2017006201A (enExample)
RU (1) RU2017120388A (enExample)
SG (1) SG11201703744VA (enExample)
WO (1) WO2016077227A2 (enExample)

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CN108753984B (zh) * 2018-08-28 2021-07-13 北京市神经外科研究所 预测或诊断脑恶性胶质瘤术后复发的生物标志物组合及其应用和试剂盒
US20230340605A1 (en) * 2020-02-04 2023-10-26 Oslo Universitetssykehus Hf Biomarkers predicting clinical response of a vegf-a inhibitory drug in cancer patients, method for their selection and use
CA3175129A1 (en) * 2020-03-12 2021-09-19 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
CA3175127A1 (en) 2020-03-12 2021-09-16 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
EP4565240A1 (en) * 2022-08-05 2025-06-11 Geistlich Pharma AG Combination therapy for treating cancers

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AU2004215133B2 (en) * 2003-02-27 2010-10-14 Yeda Research And Development Co. Ltd. Nucleic acid molecules, polypeptides, antibodies and compositions containing same useful for treating and detecting influenza virus infection
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EP2321433A2 (en) * 2008-08-29 2011-05-18 F. Hoffmann-La Roche AG Diagnostics and treatments for vegf-independent tumors
WO2011089101A1 (en) * 2010-01-19 2011-07-28 F. Hoffmann-La Roche Ag Tumor tissue based biomarkers for bevacizumab combination therapies
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CA2804350A1 (en) * 2010-07-19 2012-01-26 F. Hoffmann-La Roche Ag Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
EP2596364B1 (en) * 2010-07-19 2015-12-16 F.Hoffmann-La Roche Ag Blood plasma biomarkers for bevacizumab combination therapies for treatment of pancreatic cancer
KR20130124961A (ko) * 2010-12-09 2013-11-15 에프. 호프만-라 로슈 아게 베바시주맙 병용 치료를 위한 마커로서의 agtr1
US20140066393A1 (en) * 2011-03-01 2014-03-06 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Servic Method of selecting cancer patients for anti-angiogenesis therapy in combination with chemotherapy
SG11201402737SA (en) * 2011-12-05 2014-06-27 Hoffmann La Roche Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer

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CN107106688A (zh) 2017-08-29
IL251947A0 (en) 2017-06-29
RU2017120388A (ru) 2018-12-14
EP3218401B1 (en) 2020-03-04
US20170226198A1 (en) 2017-08-10
HK1242996A1 (zh) 2018-07-06
RU2017120388A3 (enExample) 2019-05-30
WO2016077227A3 (en) 2016-07-07
KR20170082537A (ko) 2017-07-14
SG11201703744VA (en) 2017-06-29
AU2015346652A1 (en) 2017-05-18
EP3218401A2 (en) 2017-09-20
MX2017006201A (es) 2017-07-31
CA2966216A1 (en) 2016-05-19
WO2016077227A2 (en) 2016-05-19
AR102647A1 (es) 2017-03-15
JP2017535548A (ja) 2017-11-30

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