KR20170082537A - Vegf 길항제에 대한 반응 예측 - Google Patents

Vegf 길항제에 대한 반응 예측 Download PDF

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KR20170082537A
KR20170082537A KR1020177013270A KR20177013270A KR20170082537A KR 20170082537 A KR20170082537 A KR 20170082537A KR 1020177013270 A KR1020177013270 A KR 1020177013270A KR 20177013270 A KR20177013270 A KR 20177013270A KR 20170082537 A KR20170082537 A KR 20170082537A
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cancer
patient
expression
tumor
level
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Korean (ko)
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유안유안 샤오
카를로스 바이스
연정 최
니콜라 씨. 콘살보
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제넨테크, 인크.
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C—CHEMISTRY; METALLURGY
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    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Molecular Biology (AREA)
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  • Biochemistry (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
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KR1020177013270A 2014-11-14 2015-11-09 Vegf 길항제에 대한 반응 예측 Withdrawn KR20170082537A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462079787P 2014-11-14 2014-11-14
US62/079,787 2014-11-14
PCT/US2015/059733 WO2016077227A2 (en) 2014-11-14 2015-11-09 Predicting response to a vegf antagonist

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KR20170082537A true KR20170082537A (ko) 2017-07-14

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KR1020177013270A Withdrawn KR20170082537A (ko) 2014-11-14 2015-11-09 Vegf 길항제에 대한 반응 예측

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US (1) US20170226198A1 (enExample)
EP (1) EP3218401B1 (enExample)
JP (1) JP2017535548A (enExample)
KR (1) KR20170082537A (enExample)
CN (1) CN107106688A (enExample)
AR (1) AR102647A1 (enExample)
AU (1) AU2015346652A1 (enExample)
BR (1) BR112017009633A2 (enExample)
CA (1) CA2966216A1 (enExample)
HK (1) HK1242996A1 (enExample)
IL (1) IL251947A0 (enExample)
MX (1) MX2017006201A (enExample)
RU (1) RU2017120388A (enExample)
SG (1) SG11201703744VA (enExample)
WO (1) WO2016077227A2 (enExample)

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CN108753984B (zh) * 2018-08-28 2021-07-13 北京市神经外科研究所 预测或诊断脑恶性胶质瘤术后复发的生物标志物组合及其应用和试剂盒
US20230340605A1 (en) * 2020-02-04 2023-10-26 Oslo Universitetssykehus Hf Biomarkers predicting clinical response of a vegf-a inhibitory drug in cancer patients, method for their selection and use
CA3175129A1 (en) * 2020-03-12 2021-09-19 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
CA3175127A1 (en) 2020-03-12 2021-09-16 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
EP4565240A1 (en) * 2022-08-05 2025-06-11 Geistlich Pharma AG Combination therapy for treating cancers

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EP1435965A4 (en) * 2001-09-26 2005-09-21 Intermune Inc PHARMACEUTICAL COMPOSITIONS AND METHOD FOR THE TREATMENT OF CANCER
AU2004215133B2 (en) * 2003-02-27 2010-10-14 Yeda Research And Development Co. Ltd. Nucleic acid molecules, polypeptides, antibodies and compositions containing same useful for treating and detecting influenza virus infection
EP2583685A1 (en) * 2004-06-10 2013-04-24 Regeneron Pharmaceuticals, Inc. Method of administering and using VEGF inhibitors for the treatment of human cancer
EP2321433A2 (en) * 2008-08-29 2011-05-18 F. Hoffmann-La Roche AG Diagnostics and treatments for vegf-independent tumors
WO2011089101A1 (en) * 2010-01-19 2011-07-28 F. Hoffmann-La Roche Ag Tumor tissue based biomarkers for bevacizumab combination therapies
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CA2804350A1 (en) * 2010-07-19 2012-01-26 F. Hoffmann-La Roche Ag Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
EP2596364B1 (en) * 2010-07-19 2015-12-16 F.Hoffmann-La Roche Ag Blood plasma biomarkers for bevacizumab combination therapies for treatment of pancreatic cancer
KR20130124961A (ko) * 2010-12-09 2013-11-15 에프. 호프만-라 로슈 아게 베바시주맙 병용 치료를 위한 마커로서의 agtr1
US20140066393A1 (en) * 2011-03-01 2014-03-06 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Servic Method of selecting cancer patients for anti-angiogenesis therapy in combination with chemotherapy
SG11201402737SA (en) * 2011-12-05 2014-06-27 Hoffmann La Roche Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer

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IL251947A0 (en) 2017-06-29
RU2017120388A (ru) 2018-12-14
BR112017009633A2 (pt) 2017-12-19
EP3218401B1 (en) 2020-03-04
US20170226198A1 (en) 2017-08-10
HK1242996A1 (zh) 2018-07-06
RU2017120388A3 (enExample) 2019-05-30
WO2016077227A3 (en) 2016-07-07
SG11201703744VA (en) 2017-06-29
AU2015346652A1 (en) 2017-05-18
EP3218401A2 (en) 2017-09-20
MX2017006201A (es) 2017-07-31
CA2966216A1 (en) 2016-05-19
WO2016077227A2 (en) 2016-05-19
AR102647A1 (es) 2017-03-15
JP2017535548A (ja) 2017-11-30

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