BR112017003164A2 - composição farmacêutica contendo cineol, método para tratar um paciente que sofre de rinite, uso de uma composição farmacêutica contendo cineol, e aplicador para aplicação intranasal tópica - Google Patents

composição farmacêutica contendo cineol, método para tratar um paciente que sofre de rinite, uso de uma composição farmacêutica contendo cineol, e aplicador para aplicação intranasal tópica

Info

Publication number
BR112017003164A2
BR112017003164A2 BR112017003164A BR112017003164A BR112017003164A2 BR 112017003164 A2 BR112017003164 A2 BR 112017003164A2 BR 112017003164 A BR112017003164 A BR 112017003164A BR 112017003164 A BR112017003164 A BR 112017003164A BR 112017003164 A2 BR112017003164 A2 BR 112017003164A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
cineol
containing pharmaceutical
rhinitis
applicator
Prior art date
Application number
BR112017003164A
Other languages
English (en)
Inventor
Unkauf Markus
Original Assignee
Maria Clementine Martin Klosterfrau Vertriebsges Mbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maria Clementine Martin Klosterfrau Vertriebsges Mbh filed Critical Maria Clementine Martin Klosterfrau Vertriebsges Mbh
Publication of BR112017003164A2 publication Critical patent/BR112017003164A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

a presente invenção se refere a uma composição farmacêutica contendo cineol determinada para a aplicação tópica, em particular, nasal, preferivelmente intranasal, assim como ao seu uso e a um dispositivo de aplicação contendo essa composição farmacêutica.
BR112017003164A 2014-08-18 2015-06-25 composição farmacêutica contendo cineol, método para tratar um paciente que sofre de rinite, uso de uma composição farmacêutica contendo cineol, e aplicador para aplicação intranasal tópica BR112017003164A2 (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE102014012040 2014-08-18
DE102014012278 2014-08-22
DE102014013145 2014-09-10
DE102014013189 2014-09-11
DE102014116903.4A DE102014116903A1 (de) 2014-08-18 2014-11-19 Cineolhaltige Zusammensetzung für die nasale Applikation
PCT/EP2015/064373 WO2016026600A1 (de) 2014-08-18 2015-06-25 Cineolhaltige zusammensetzung für die nasale applikation

Publications (1)

Publication Number Publication Date
BR112017003164A2 true BR112017003164A2 (pt) 2017-11-28

Family

ID=54067266

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017003164A BR112017003164A2 (pt) 2014-08-18 2015-06-25 composição farmacêutica contendo cineol, método para tratar um paciente que sofre de rinite, uso de uma composição farmacêutica contendo cineol, e aplicador para aplicação intranasal tópica

Country Status (12)

Country Link
US (1) US20170273935A1 (pt)
EP (2) EP3300722B1 (pt)
JP (1) JP6469843B2 (pt)
KR (1) KR20170036058A (pt)
BR (1) BR112017003164A2 (pt)
CL (1) CL2017000394A1 (pt)
DE (2) DE102014116903A1 (pt)
EA (1) EA033510B1 (pt)
ES (2) ES2764506T3 (pt)
MX (1) MX2017002239A (pt)
PL (1) PL3182957T3 (pt)
WO (1) WO2016026600A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202015104410U1 (de) * 2015-07-06 2016-07-13 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Zusammensetzung für die Behandlung von Rhinitis
DE202015104761U1 (de) * 2015-09-01 2016-09-02 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Cineolhaltige wässrige Zusammensetzung für die nasale Applikation
DE202015106123U1 (de) * 2015-10-23 2016-10-27 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Monoterpenhaltige Zusammensetzung zur Behandlung von Erkrankungen der Nase
US20200246311A1 (en) * 2017-08-10 2020-08-06 Elixir Ilac Arastirma Ve Gelistirme A.S. Nasal decongestant compositions comprising dexpanthenol and sodium hyaluronate
EP3552601A1 (de) * 2018-04-11 2019-10-16 Karl Bodenschatz Pharmazeutische zusammensetzung enthaltend dexpanthenol und polihexanid
AT16516U1 (de) * 2019-03-18 2019-11-15 Ulrich Sekotill Mba Nasenspray
US20220080020A1 (en) * 2020-08-22 2022-03-17 Luc Montagnier Compositions and methods for reducing the transmissivity of illnesses using an oral delivery system
CN112220102B (zh) * 2020-09-25 2022-12-09 山东华熙海御生物医药有限公司 一种含透明质酸和依克多因的电子烟液及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1811868A (en) * 1928-08-21 1931-06-30 Rheinische Kampfer Fabrik Process for preparing 1,8-cineol
GB1514469A (en) * 1974-08-01 1978-06-14 Beecham Group Ltd Oral hygiene compositions
HU203667B (en) * 1986-12-11 1991-09-30 Roussel Uclaf Process for producing synergetic zootechnical compositions containing three components
US5114979A (en) * 1989-10-18 1992-05-19 Schering Corporation Fruity flavored nasal decongestant composition
WO1995013810A1 (en) * 1993-11-19 1995-05-26 Schering-Plough Healthcare Products Incorporated Nasal spray compositions containing oxymetazoline
DE19549421C2 (de) 1995-11-10 1999-11-18 Klosterfrau Mcm Vetrieb Gmbh Pharmazeutische Zubereitung zur Behandlung akuter Rhinitiden
DE19541919C2 (de) 1995-11-10 1997-11-20 Klosterfrau Mcm Vetrieb Gmbh Pharmazeutische Zubereitung zur Behandlung akuter Rhinitiden
DE10107659B4 (de) * 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin
JP2004196676A (ja) * 2002-12-16 2004-07-15 Rohto Pharmaceut Co Ltd 点鼻剤
DE10356248A1 (de) 2003-11-13 2005-06-23 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Pharmazeutische Zusammensetzung zur Behandlung von Rhinitiden
DE102007040615A1 (de) * 2007-08-27 2009-03-05 Bitop Ag Osmolyte zur Behandlung von allergisch oder viral bedingten Atemwegserkrankungen
CN101292976B (zh) * 2008-06-26 2010-07-28 贵州宏宇药业有限公司 一种含有1,8-桉叶素和艾纳香素的药物组合物及其用途
IT1391170B1 (it) * 2008-08-07 2011-11-18 D M G Italia S R L Composizione topica intra-nasale utilizzabile in caso di ostruzione nasale
DE102012005452A1 (de) * 2011-12-30 2013-07-04 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Zusammensetzung für die nasale Applikation mit verbesserter Stabilität
DE102013001151A1 (de) * 2013-01-24 2014-07-24 Merz Pharma Gmbh & Co. Kgaa Sprühbare flüssige Zubereitung zur insbesondere nasalen Anwendung mit erhöhter lokaler Verweilzeit

Also Published As

Publication number Publication date
JP6469843B2 (ja) 2019-02-13
EP3300722A1 (de) 2018-04-04
ES2834985T3 (es) 2021-06-21
DE102014116903A1 (de) 2016-02-18
PL3182957T3 (pl) 2020-05-18
EA201790410A1 (ru) 2017-10-31
DE202014105553U1 (de) 2015-08-20
EP3300722B1 (de) 2020-09-16
US20170273935A1 (en) 2017-09-28
KR20170036058A (ko) 2017-03-31
EP3182957B1 (de) 2019-10-16
JP2017525701A (ja) 2017-09-07
EP3182957A1 (de) 2017-06-28
ES2764506T3 (es) 2020-06-03
EA033510B1 (ru) 2019-10-31
WO2016026600A1 (de) 2016-02-25
MX2017002239A (es) 2017-05-09
CL2017000394A1 (es) 2017-11-03

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements