BR112017002703A2 - anticorpos específicos de mmp9. - Google Patents
anticorpos específicos de mmp9.Info
- Publication number
- BR112017002703A2 BR112017002703A2 BR112017002703-8A BR112017002703A BR112017002703A2 BR 112017002703 A2 BR112017002703 A2 BR 112017002703A2 BR 112017002703 A BR112017002703 A BR 112017002703A BR 112017002703 A2 BR112017002703 A2 BR 112017002703A2
- Authority
- BR
- Brazil
- Prior art keywords
- mmp9
- specific antibodies
- fragment
- useful
- chain variable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24035—Gelatinase B (3.4.24.35), i.e. matrix metalloprotease 9 or MMP9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
- G01N2333/96491—Metalloendopeptidases (3.4.24) with definite EC number
- G01N2333/96494—Matrix metalloproteases, e. g. 3.4.24.7
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14180765.1 | 2014-08-13 | ||
EP14180765.1A EP2985296A1 (en) | 2014-08-13 | 2014-08-13 | Antibodies specific for MMP9 |
PCT/EP2015/068645 WO2016023979A1 (en) | 2014-08-13 | 2015-08-13 | Antibodies specific for mmp9 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017002703A2 true BR112017002703A2 (pt) | 2018-02-27 |
Family
ID=51301193
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017002703-8A BR112017002703A2 (pt) | 2014-08-13 | 2015-08-13 | anticorpos específicos de mmp9. |
Country Status (13)
Country | Link |
---|---|
US (1) | US10364296B2 (pt) |
EP (2) | EP2985296A1 (pt) |
JP (1) | JP6856523B2 (pt) |
KR (1) | KR20170041222A (pt) |
CN (1) | CN106573984A (pt) |
AU (1) | AU2015303183B2 (pt) |
BR (1) | BR112017002703A2 (pt) |
CA (1) | CA2956986A1 (pt) |
ES (1) | ES2784271T3 (pt) |
MX (1) | MX2017001959A (pt) |
PL (1) | PL3180362T3 (pt) |
RU (1) | RU2714043C2 (pt) |
WO (1) | WO2016023979A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20170306050A1 (en) | 2016-04-08 | 2017-10-26 | Gilead Sciences, Inc. | Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases |
WO2018109222A1 (en) | 2016-12-16 | 2018-06-21 | Universite de Bordeaux | Mmp9 inhibitors and uses thereof in the prevention or treatment of a depigmenting disorder |
WO2018220235A1 (en) * | 2017-06-02 | 2018-12-06 | Merck Patent Gmbh | Mmp13 binding immunoglobulins |
US20200124604A1 (en) * | 2017-06-30 | 2020-04-23 | National Institutes Of Biomedical Innovation, Health And Nutrition | Biomarker for detecting colorectal cancer |
JP7109440B2 (ja) * | 2017-07-18 | 2022-07-29 | 第一三共株式会社 | 活性型mmp-9結合ペプチド |
JP2021506763A (ja) * | 2017-12-13 | 2021-02-22 | ノース カロライナ ステート ユニバーシティNorth Carolina State University | 化学療法剤とチェックポイント阻害剤とを含む組成物及び使用の方法 |
CN108277214B (zh) * | 2018-02-23 | 2021-07-06 | 广东医科大学 | 一种应激磷酸化抗原多肽、抗体、制备方法以及应用 |
WO2020237092A2 (en) * | 2019-05-21 | 2020-11-26 | The Regents Of The University Of California | Mmp-9 antibodies and methods of use thereof |
CN110885375B (zh) * | 2019-12-20 | 2021-07-02 | 南京融捷康生物科技有限公司 | 特异性针对mmp-9蛋白锌离子结合结构域的单域抗体及产品与应用 |
WO2023278491A1 (en) * | 2021-06-28 | 2023-01-05 | Releviate, Llc | Mmp-9 antibodies and uses thereof |
CN117327186B (zh) * | 2023-07-12 | 2024-03-12 | 北京达成生物科技有限公司 | 结合mmp3蛋白的双特异性抗体及其用途 |
CN117264069B (zh) * | 2023-11-23 | 2024-01-26 | 再少年(北京)生物科技有限公司 | 一种促进皮肤组织再生的工程化外泌体的制备方法及其应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002235692A1 (en) * | 2001-02-23 | 2002-09-04 | Biophage Inc. | Methods and compositions for preventing and treating neutrophil-mediated diseases |
GB0516069D0 (en) | 2005-08-04 | 2005-09-14 | Imp College Innovations Ltd | Pharmaceutical and use thereof |
KR20090113908A (ko) * | 2007-02-23 | 2009-11-02 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | 금속단백질 활성 억제용 항체 및 이를 함유하는 약학적 조성물 |
US8013125B2 (en) | 2008-03-03 | 2011-09-06 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
US8008445B2 (en) | 2008-03-03 | 2011-08-30 | Dyax Corp. | Metalloproteinase 9 binding proteins |
WO2010045388A2 (en) * | 2008-10-14 | 2010-04-22 | Dyax Corp. | Use of mmp-9 and mmp-12 binding proteins for the treatment and prevention of systemic sclerosis |
WO2011028883A2 (en) * | 2009-09-03 | 2011-03-10 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
PT2608809T (pt) * | 2010-08-27 | 2019-08-26 | Gilead Biologics Inc | Anticorpos para a metaloproteinase 9 da matriz |
MX2014010449A (es) | 2012-02-29 | 2015-02-10 | Gilead Biologics Inc | Anticuerpos a metaloproteinasa de matriz 9. |
NZ629178A (en) * | 2012-02-29 | 2016-09-30 | Gilead Biologics Inc | Antibodies to matrix metalloproteinase 9 |
-
2014
- 2014-08-13 EP EP14180765.1A patent/EP2985296A1/en not_active Withdrawn
-
2015
- 2015-08-13 ES ES15749818T patent/ES2784271T3/es active Active
- 2015-08-13 CA CA2956986A patent/CA2956986A1/en not_active Abandoned
- 2015-08-13 KR KR1020177004988A patent/KR20170041222A/ko not_active Application Discontinuation
- 2015-08-13 US US15/503,447 patent/US10364296B2/en not_active Expired - Fee Related
- 2015-08-13 RU RU2017107773A patent/RU2714043C2/ru active
- 2015-08-13 CN CN201580043394.1A patent/CN106573984A/zh active Pending
- 2015-08-13 PL PL15749818T patent/PL3180362T3/pl unknown
- 2015-08-13 AU AU2015303183A patent/AU2015303183B2/en not_active Ceased
- 2015-08-13 EP EP15749818.9A patent/EP3180362B1/en active Active
- 2015-08-13 BR BR112017002703-8A patent/BR112017002703A2/pt not_active IP Right Cessation
- 2015-08-13 WO PCT/EP2015/068645 patent/WO2016023979A1/en active Application Filing
- 2015-08-13 JP JP2017508053A patent/JP6856523B2/ja active Active
- 2015-08-13 MX MX2017001959A patent/MX2017001959A/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP3180362B1 (en) | 2020-02-05 |
KR20170041222A (ko) | 2017-04-14 |
ES2784271T3 (es) | 2020-09-23 |
JP2017532005A (ja) | 2017-11-02 |
JP6856523B2 (ja) | 2021-04-07 |
PL3180362T3 (pl) | 2020-06-15 |
CN106573984A (zh) | 2017-04-19 |
RU2017107773A3 (pt) | 2018-09-13 |
RU2714043C2 (ru) | 2020-02-11 |
US10364296B2 (en) | 2019-07-30 |
MX2017001959A (es) | 2017-05-04 |
AU2015303183B2 (en) | 2021-01-28 |
EP2985296A1 (en) | 2016-02-17 |
EP3180362A1 (en) | 2017-06-21 |
CA2956986A1 (en) | 2016-02-18 |
RU2017107773A (ru) | 2018-09-13 |
US20170233495A1 (en) | 2017-08-17 |
AU2015303183A1 (en) | 2017-02-16 |
WO2016023979A1 (en) | 2016-02-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: CALYPSO BIOTECH SA (CH) |
|
B25A | Requested transfer of rights approved |
Owner name: EA PHARMA CO., LTD. (JP) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2735 DE 06-06-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |