BR112016009062A2 - Composição antibacteriana, método para a preparação de uma composição, método para prever ou determinar a eficácia de uma terapia de bacteriófago em um indivíduo, método para selecionar um indivíduo ou determinar se um indivíduo é susceptível de se beneficiar de uma terapia com bacteriófagos, bacteriófago, ácido nucleico isolado, e, polipeptídeo isolado - Google Patents

Composição antibacteriana, método para a preparação de uma composição, método para prever ou determinar a eficácia de uma terapia de bacteriófago em um indivíduo, método para selecionar um indivíduo ou determinar se um indivíduo é susceptível de se beneficiar de uma terapia com bacteriófagos, bacteriófago, ácido nucleico isolado, e, polipeptídeo isolado

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Publication number
BR112016009062A2
BR112016009062A2 BR112016009062A BR112016009062A BR112016009062A2 BR 112016009062 A2 BR112016009062 A2 BR 112016009062A2 BR 112016009062 A BR112016009062 A BR 112016009062A BR 112016009062 A BR112016009062 A BR 112016009062A BR 112016009062 A2 BR112016009062 A2 BR 112016009062A2
Authority
BR
Brazil
Prior art keywords
bacteriophages
individual
therapy
composition
determining
Prior art date
Application number
BR112016009062A
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English (en)
Other versions
BR112016009062B1 (pt
Inventor
Pouillot Flavie
Blois Hélène
Original Assignee
Pherecydes Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pherecydes Pharma filed Critical Pherecydes Pharma
Publication of BR112016009062A2 publication Critical patent/BR112016009062A2/pt
Publication of BR112016009062B1 publication Critical patent/BR112016009062B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10171—Demonstrated in vivo effect
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10211—Podoviridae
    • C12N2795/10221—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10211—Podoviridae
    • C12N2795/10222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10211—Podoviridae
    • C12N2795/10232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10211—Podoviridae
    • C12N2795/10271—Demonstrated in vivo effect
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

COMPOSIÇÃO ANTIBACTERIANA, MÉTODO PARA A PREPARAÇÃO DE UMA COMPOSIÇÃO, MÉTODO PARA PREVER OU DETERMINAR A EFICÁCIA DE UMA TERAPIA DE BACTERIÓFAGO EM UM INDIVÍDUO, MÉTODO PARA SELECIONAR UM INDIVÍDUO OU DETERMINAR SE UM INDIVÍDUO É SUSCEPTÍVEL DE SE BENEFICIAR DE UMA TERAPIA COM BACTERIÓFAGOS, BACTERIÓFAGO, ÁCIDO NUCLEICO ISOLADO, E, POLIPEPTÍDEO ISOLADO. A presente invenção se refere a terapia com bacteriófagos. Mais particularmente, a presente invenção se refere a novos bacteriófagos que têm uma alta especificidade contra as cepas de Pseudomonas aeruginosa, a sua produção, componentes dos mesmos, composições compreendendo os mesmos e os seus usos na fagoterapia.
BR112016009062-4A 2013-10-25 2014-10-24 Composição antibacteriana, método para a preparação de uma composição, método in vitro para prever ou determinar a eficácia de uma terapia de bacteriófago em um indivíduo e método in vitro para selecionar um indivíduo ou determinar se um indivíduo é susceptível de se beneficiar de uma terapia com bacteriófagos BR112016009062B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20130306471 EP2865383A1 (en) 2013-10-25 2013-10-25 Phage therapy of pseudomonas infections
EP13306471.7 2013-10-25
PCT/EP2014/072905 WO2015059298A1 (en) 2013-10-25 2014-10-24 Phage therapy of pseudomonas infections

Publications (2)

Publication Number Publication Date
BR112016009062A2 true BR112016009062A2 (pt) 2017-09-19
BR112016009062B1 BR112016009062B1 (pt) 2023-10-10

Family

ID=49551569

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016009062-4A BR112016009062B1 (pt) 2013-10-25 2014-10-24 Composição antibacteriana, método para a preparação de uma composição, método in vitro para prever ou determinar a eficácia de uma terapia de bacteriófago em um indivíduo e método in vitro para selecionar um indivíduo ou determinar se um indivíduo é susceptível de se beneficiar de uma terapia com bacteriófagos

Country Status (16)

Country Link
US (2) US10077431B2 (pt)
EP (2) EP2865383A1 (pt)
JP (2) JP6745222B2 (pt)
CN (1) CN108697744B (pt)
AU (1) AU2014338859B2 (pt)
BR (1) BR112016009062B1 (pt)
CA (1) CA2928540C (pt)
DK (1) DK3060226T3 (pt)
ES (1) ES2857199T3 (pt)
HU (1) HUE053522T2 (pt)
IL (1) IL245085B (pt)
LT (1) LT3060226T (pt)
PL (1) PL3060226T3 (pt)
PT (1) PT3060226T (pt)
SI (1) SI3060226T1 (pt)
WO (1) WO2015059298A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2893933A1 (en) 2014-01-10 2015-07-15 Pherecydes Pharma Phage Therapy of E coli infections
EP3018201A1 (en) * 2014-11-07 2016-05-11 Pherecydes Pharma Phage therapy
US11457635B2 (en) * 2017-02-17 2022-10-04 Intron Biotechnology, Inc. Pseudomonas aeruginosa bacteriophage Pse-AEP-3 and use thereof for inhibiting proliferation of Pseudomonas aeruginosa
EP3372085A1 (en) 2017-03-08 2018-09-12 Pherecydes Pharma Phage therapy
US10574580B2 (en) * 2017-07-04 2020-02-25 Vmware, Inc. Network resource management for hyper-converged infrastructures
AU2019205241A1 (en) * 2018-01-02 2020-07-16 Armata Pharmaceuticals, Inc. Bacteriophage compositions for treating Pseudomonas infections
CN108070572A (zh) * 2018-01-25 2018-05-25 青岛诺安百特生物技术有限公司 一种宽裂解谱绿脓杆菌噬菌体及其消毒应用
CN116018154A (zh) * 2020-04-27 2023-04-25 阿玛塔制药公司 用于治疗假单胞菌属感染的噬菌体组合物
WO2022208369A1 (en) * 2021-03-30 2022-10-06 Biomx Ltd. Pseudomonas bacteriophage and uses thereof
WO2024033686A1 (en) * 2022-08-11 2024-02-15 Phagelab Chile Spa Bacteriophages and compositions thereof for controlling the growth of pseudomonas lundensis in meat products

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5701777B2 (ja) * 2009-02-06 2015-04-15 テクノファージ， インベスティガサン エ デセンボルビメント エム ビオテクノロジア，エスエー 抗菌性ファージ、ファージペプチド、及びそれらの使用方法
PL3789031T3 (pl) * 2010-09-17 2024-01-15 Technophage, Investigação E Desenvolvimento Em Biotecnologia, Sa Antybakteryjny fag, peptydy fagowe i sposoby ich zastosowania
EP2465926A1 (en) * 2010-12-20 2012-06-20 University College Cork Pseudomonas aeruginosa Bacteriophage and uses thereof
JP6186427B2 (ja) * 2012-03-19 2017-08-23 テクニファー−インダストリア テクニカ ファーマシューティカ，エス．エー． 抗菌性ファージのカクテルを含む組成物及び細菌感染症を処置するためのその使用

Also Published As

Publication number Publication date
US20160264941A1 (en) 2016-09-15
US10260051B2 (en) 2019-04-16
BR112016009062B1 (pt) 2023-10-10
JP2016537405A (ja) 2016-12-01
WO2015059298A1 (en) 2015-04-30
SI3060226T1 (sl) 2021-07-30
CN108697744B (zh) 2022-04-01
HUE053522T2 (hu) 2021-07-28
JP2020143119A (ja) 2020-09-10
EP3060226B1 (en) 2020-12-16
IL245085A0 (en) 2016-06-30
EP2865383A1 (en) 2015-04-29
US20190002840A1 (en) 2019-01-03
CN108697744A (zh) 2018-10-23
JP7321970B2 (ja) 2023-08-07
EP3060226A1 (en) 2016-08-31
JP6745222B2 (ja) 2020-08-26
ES2857199T3 (es) 2021-09-28
AU2014338859A1 (en) 2016-05-12
AU2014338859B2 (en) 2018-07-26
LT3060226T (lt) 2021-04-26
US10077431B2 (en) 2018-09-18
CA2928540C (en) 2024-05-07
IL245085B (en) 2020-08-31
DK3060226T3 (da) 2021-03-01
PL3060226T3 (pl) 2021-10-18
CA2928540A1 (en) 2015-04-30
PT3060226T (pt) 2021-03-04

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/10/2014, OBSERVADAS AS CONDICOES LEGAIS