BR112016000431A8 - composições e métodos para o tratamento de distúrbios neuropsiquiátricos usando um agonista do receptor de endotelina-b - Google Patents

composições e métodos para o tratamento de distúrbios neuropsiquiátricos usando um agonista do receptor de endotelina-b

Info

Publication number
BR112016000431A8
BR112016000431A8 BR112016000431A BR112016000431A BR112016000431A8 BR 112016000431 A8 BR112016000431 A8 BR 112016000431A8 BR 112016000431 A BR112016000431 A BR 112016000431A BR 112016000431 A BR112016000431 A BR 112016000431A BR 112016000431 A8 BR112016000431 A8 BR 112016000431A8
Authority
BR
Brazil
Prior art keywords
endothelin
methods
compositions
receptor agonist
neuropsychiatric disorders
Prior art date
Application number
BR112016000431A
Other languages
English (en)
Inventor
Gulati Anil
Original Assignee
Univ Midwestern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Midwestern filed Critical Univ Midwestern
Publication of BR112016000431A8 publication Critical patent/BR112016000431A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2285—Endothelin, vasoactive intestinal contractor [VIC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

resumo composições e métodos para o tratamento de distúrbios neuropsiquiátricos usando um agonista do receptor de endotelina-b a presente invenção se refere a composições e métodos para o tratamento de distúrbios neuropsiquiátricos em vertebrados e seres humanos. mais especificamente, a presente invenção proporciona o uso de um agonista do receptor de endotelina-b como um agente neuroprotetor e neurorregenerativo.
BR112016000431A 2013-07-08 2014-07-08 composições e métodos para o tratamento de distúrbios neuropsiquiátricos usando um agonista do receptor de endotelina-b BR112016000431A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361843702P 2013-07-08 2013-07-08
US201361902935P 2013-11-12 2013-11-12
PCT/US2014/045748 WO2015006324A2 (en) 2013-07-08 2014-07-08 Compositions and methods for treating neuropsychiatric disorders using an endothelin-b receptor agonist

Publications (1)

Publication Number Publication Date
BR112016000431A8 true BR112016000431A8 (pt) 2018-01-23

Family

ID=52280704

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016000431A BR112016000431A8 (pt) 2013-07-08 2014-07-08 composições e métodos para o tratamento de distúrbios neuropsiquiátricos usando um agonista do receptor de endotelina-b

Country Status (10)

Country Link
US (2) US10561704B2 (pt)
EP (1) EP3019242B1 (pt)
JP (2) JP6928450B2 (pt)
CN (2) CN105682741A (pt)
AU (1) AU2014287427B2 (pt)
BR (1) BR112016000431A8 (pt)
CA (2) CA2917325C (pt)
ES (1) ES2825101T3 (pt)
PL (1) PL3019242T3 (pt)
WO (1) WO2015006324A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2424529T3 (pl) 2009-04-30 2017-06-30 Midwestern University Nowe postępowania terapeutyczne z zastosowaniem centakwiny
ES2978951T3 (es) * 2018-05-03 2024-09-23 Univ Midwestern Composición que comprende centaquina o una sal de la misma para su uso en el tratamiento de un individuo que padece disminución aguda de la función renal
US20240207356A1 (en) * 2022-12-26 2024-06-27 Pharmazz, Inc. Composition and method for wound healing and repair of damaged nerves
WO2024057296A2 (en) 2023-06-28 2024-03-21 Pharmazz, Inc. Lyophilized sovateltide-based injectable formulation and a process for preparation

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3954987A (en) 1972-12-22 1976-05-04 Sandoz, Inc. 2-Alkyl-4-substituted amino-quinazolines and nitrates thereof in the treatment of myocardial shock
US3983121A (en) 1974-07-01 1976-09-28 Council Of Scientific And Industrial Research 1-Substituted 4-(β-2-quinolylethyl)piperazines and 1,2,3,4-tetrahydroquinolyl-ethyl analogues thereof
DE2557784C2 (de) 1975-12-22 1986-04-17 Hoechst Ag, 6230 Frankfurt Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate
US4761417A (en) 1982-05-14 1988-08-02 Maroko Peter R Compounds, compositions and method of treatments for improving circulatory performance
US5055470A (en) 1989-06-01 1991-10-08 Bristol-Myers Squibb Co. Method of treatment of ischemia in brain
US5922681A (en) 1992-09-14 1999-07-13 Warner-Lambert Company Endothelin antagonists
US20040063719A1 (en) 1998-08-26 2004-04-01 Queen's University At Kingston Combination therapy using antihypertensive agents and endothelin antagonists
US6545048B1 (en) * 1999-06-29 2003-04-08 California Institute Of Technology Compositions and methods of treating cancer using compositions comprising an inhibitor or endothelin receptor activity
US6113915A (en) 1999-10-12 2000-09-05 Allergan Sales, Inc. Methods for treating pain
SE0004455D0 (sv) 2000-12-01 2000-12-01 Milos Pekny Method for neuron regeneration in the central nervous system
US6573285B2 (en) 2000-12-21 2003-06-03 Bristol-Myers Squibb Co. Method for preventing or treating pain by administering an endothelin antagonist
US20030232787A1 (en) 2001-05-08 2003-12-18 Dooley David James Combinations of an endothelin receptor antagonist and an antiepileptic compound having pain alleviating properties or analgesic
US20030104976A1 (en) 2001-07-23 2003-06-05 Gudarz Davar Analgesic methods using endothelin receptor ligands
US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
US7973064B2 (en) 2001-11-27 2011-07-05 The Board Of Trustees Of The University Of Illinois Method and composition for potentiating an opiate analgesic
US7351692B2 (en) 2002-06-19 2008-04-01 The Board Of Trustees Of The University Of Illinois Method and composition for potentiating the antipyretic action of a nonopioid analgesic
CN1729012B (zh) 2002-10-24 2013-05-22 伊利诺伊大学评议会 治疗实体瘤的组合物
EP1583541B1 (en) * 2002-11-20 2011-01-12 NeuroNova AB Compounds and methods for increasing neurogenesis
WO2008043102A2 (en) 2006-10-06 2008-04-10 Transition Therapeutics Inc. Vasoactive intestinal polypeptide compositions
AU2007230887A1 (en) * 2006-03-23 2007-10-04 Amylin Pharmaceuticals, Inc. Endothelin and endothelin receptor agonists in the treatment of metabolic diseases
CN101888851B (zh) * 2007-08-21 2013-11-20 美国中西部大学 使用内皮缩血管肽b受体激动剂治疗中风或脑血管意外的组合物
CN101374259B (zh) * 2007-08-22 2012-08-08 华为技术有限公司 实现多媒体彩铃和多媒体彩像业务的方法和装置
KR101418941B1 (ko) 2011-04-04 2014-07-15 서울대학교병원 엔도텔린을 유효성분으로 함유하는 허혈성질환 치료용 조성물

Also Published As

Publication number Publication date
CA2917325C (en) 2023-09-05
CA3171883A1 (en) 2015-01-15
JP7385924B2 (ja) 2023-11-24
JP6928450B2 (ja) 2021-09-01
EP3019242A2 (en) 2016-05-18
CA3171883C (en) 2024-03-05
CA2917325A1 (en) 2015-01-15
CN113384701A (zh) 2021-09-14
US20200353031A1 (en) 2020-11-12
PL3019242T3 (pl) 2021-02-08
JP2016523969A (ja) 2016-08-12
WO2015006324A8 (en) 2016-01-28
US20160151450A1 (en) 2016-06-02
US10561704B2 (en) 2020-02-18
JP2021020945A (ja) 2021-02-18
EP3019242A4 (en) 2017-01-25
WO2015006324A2 (en) 2015-01-15
AU2014287427A1 (en) 2016-02-11
AU2014287427B2 (en) 2019-11-21
WO2015006324A3 (en) 2015-11-05
EP3019242B1 (en) 2020-08-19
ES2825101T3 (es) 2021-05-14
CN105682741A (zh) 2016-06-15

Similar Documents

Publication Publication Date Title
PH12015501846A1 (en) Novel antibody conjugates and uses thereof
CL2016000807A1 (es) Amino heteroarilo benzamidas como inhibidores de quinasa.
HK1215378A1 (zh) 藥物組合物、治療方法及其用途
CL2016000341A1 (es) Métodos para tratar la miositis por cuerpos de inclusión esporádica
MX2017001457A (es) Divisores de union dinamicos para ventanas de aplicacion.
CL2015003280A1 (es) Derivados de benzimidazol como inhibidores de bromodominio
CL2015001985A1 (es) Compuestos de tiazolcarboxamidas y piridinacarboxamida, inhibidores de quinasa pim.
CL2015003801A1 (es) Formulaciones de anticuerpos y metodos
PH12016500781A1 (en) Novel anti-claudin antibodies and methods of use
TR201902516T4 (tr) Glukagon-glp-1-gıp üçlü agonist bileşikleri.
MX2016007369A (es) Nuevos anticuerpos anti-dpep3 y metodos de uso.
CL2015003343A1 (es) Composición farmacéutica que comprende un agente terapéutico modificado en base a hemoglobina, para el tratamiento para tratar el cáncer, e imágenes de diagnóstico.
CL2016001151A1 (es) Derivados de purina 2,6-sustituidos y su uso en el tratamiento de trastorno proliferativos.
ECSP16012582A (es) Compuestos heterocíclicos y métodos de uso
CL2016000351A1 (es) Método para la cuantificación de actinio-227 en composiciones de radio-223.
NZ702415A (en) Methods for treating neutropenia using retinoid agonists
MX2016008150A (es) Formulaciones de berberina y usos de las mismas.
BR112016000431A8 (pt) composições e métodos para o tratamento de distúrbios neuropsiquiátricos usando um agonista do receptor de endotelina-b
CL2016001570A1 (es) Uso de un antagonista de receptores de opioides con actividad %u039a y vortioxetina para el tratamiento de trastorno depresivo con características melancólicas
BR112015022513A2 (pt) produto e método para tratamento de diarreia
EA201591709A1 (ru) 5-бром-индирубины
BR112015021722A2 (pt) composição para uso no tratamento de síndrome do ovário policístico
CY1120178T1 (el) Αγωγη εμμηνοπαυσιακων εξαψεων με ροπινιρολη και τιζανιδινη
UY35823A (es) Profármacos de antagonista de nmda
MX2016009464A (es) Composiciones para el uso en el tratamiento de afecciones alergicas.

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]