BR112015023672A2 - análogo de insulina, orto-fluoro, sequência de dna codificando a cadeia a de análogo de insulina, sequência de dna codificando a cadeia b de análogo de insulina e uso de um análogo de insulina. - Google Patents

análogo de insulina, orto-fluoro, sequência de dna codificando a cadeia a de análogo de insulina, sequência de dna codificando a cadeia b de análogo de insulina e uso de um análogo de insulina.

Info

Publication number
BR112015023672A2
BR112015023672A2 BR112015023672A BR112015023672A BR112015023672A2 BR 112015023672 A2 BR112015023672 A2 BR 112015023672A2 BR 112015023672 A BR112015023672 A BR 112015023672A BR 112015023672 A BR112015023672 A BR 112015023672A BR 112015023672 A2 BR112015023672 A2 BR 112015023672A2
Authority
BR
Brazil
Prior art keywords
insulin analog
chain
sequence encoding
dna sequence
insulin
Prior art date
Application number
BR112015023672A
Other languages
English (en)
Portuguese (pt)
Inventor
a weiss Michael
Original Assignee
Univ Case Western Reserve
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Case Western Reserve filed Critical Univ Case Western Reserve
Publication of BR112015023672A2 publication Critical patent/BR112015023672A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BR112015023672A 2013-03-15 2014-03-17 análogo de insulina, orto-fluoro, sequência de dna codificando a cadeia a de análogo de insulina, sequência de dna codificando a cadeia b de análogo de insulina e uso de um análogo de insulina. BR112015023672A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361798165P 2013-03-15 2013-03-15
PCT/US2014/030387 WO2014145593A2 (en) 2013-03-15 2014-03-17 Site 2 insulin analogues

Publications (1)

Publication Number Publication Date
BR112015023672A2 true BR112015023672A2 (pt) 2017-07-18

Family

ID=51538504

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015023672A BR112015023672A2 (pt) 2013-03-15 2014-03-17 análogo de insulina, orto-fluoro, sequência de dna codificando a cadeia a de análogo de insulina, sequência de dna codificando a cadeia b de análogo de insulina e uso de um análogo de insulina.

Country Status (10)

Country Link
US (1) US20160083448A1 (https=)
EP (1) EP2968473A4 (https=)
JP (1) JP2016516728A (https=)
KR (1) KR20150138251A (https=)
CN (1) CN105228643A (https=)
AU (1) AU2014232894B2 (https=)
BR (1) BR112015023672A2 (https=)
CA (1) CA2942524A1 (https=)
IL (1) IL241357B (https=)
WO (1) WO2014145593A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015106269A2 (en) 2014-01-13 2015-07-16 Thermalin Diabetes, Llc Rapid action insulin formulations and pharmaceutical delivery systems
CN107428814A (zh) * 2015-01-20 2017-12-01 卡斯西部储备大学 具有选择性信号传导特性和降低的促有丝分裂性的胰岛素类似物
CR20190096A (es) 2016-07-22 2019-09-16 Walter & Eliza Hall Inst Medical Res Análogos de insulina
MA46568A (fr) * 2016-10-24 2019-08-28 Novo Nordisk As Dosage biologique de formulations d'insuline
MY200047A (en) 2016-11-21 2023-12-06 Univ Case Western Reserve Rapid-acting insulin analogues of enhanced stability
WO2020061554A1 (en) * 2018-09-21 2020-03-26 Case Western Reserve University Site 2 single-chain insulin analogues

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK158390D0 (da) * 1990-07-02 1990-07-02 Novo Nordisk As Nye peptider
DK10191D0 (da) * 1991-01-22 1991-01-22 Novo Nordisk As Hidtil ukendte peptider
DK33591D0 (https=) * 1991-02-27 1991-02-27 Novo Nordisk As
ES2542146T3 (es) 2006-07-31 2015-07-31 Novo Nordisk A/S Insulinas extendidas PEGiladas.
EP2074140B8 (en) 2006-10-04 2015-10-28 Case Western Reserve University Fibrillation-resistant insulin and insulin analogues
US8993516B2 (en) * 2008-04-14 2015-03-31 Case Western Reserve University Meal-time insulin analogues of enhanced stability
RU2010147076A (ru) * 2008-04-22 2012-05-27 Кейз Вестерн Ризев Юнивесити (Us) Аналоги инсулина специфичные к изоформам
CA2732439A1 (en) * 2008-07-31 2010-02-04 Case Western Reserve University Halogen-stabilized insulin

Also Published As

Publication number Publication date
US20160083448A1 (en) 2016-03-24
JP2016516728A (ja) 2016-06-09
EP2968473A2 (en) 2016-01-20
WO2014145593A3 (en) 2015-01-08
AU2014232894A1 (en) 2015-11-05
KR20150138251A (ko) 2015-12-09
CA2942524A1 (en) 2014-09-18
WO2014145593A2 (en) 2014-09-18
EP2968473A4 (en) 2016-11-23
AU2014232894B2 (en) 2018-02-08
IL241357A0 (en) 2015-11-30
IL241357B (en) 2021-08-31
CN105228643A (zh) 2016-01-06

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements