BR112015023381A2 - composição de liberação imediata de sovaprevir, composição de sovaprevir de 200 mg, núcleo de comprimido de sovaprevir e comprimido de sovaprevir revestido - Google Patents
composição de liberação imediata de sovaprevir, composição de sovaprevir de 200 mg, núcleo de comprimido de sovaprevir e comprimido de sovaprevir revestidoInfo
- Publication number
- BR112015023381A2 BR112015023381A2 BR112015023381A BR112015023381A BR112015023381A2 BR 112015023381 A2 BR112015023381 A2 BR 112015023381A2 BR 112015023381 A BR112015023381 A BR 112015023381A BR 112015023381 A BR112015023381 A BR 112015023381A BR 112015023381 A2 BR112015023381 A2 BR 112015023381A2
- Authority
- BR
- Brazil
- Prior art keywords
- sovaprevir
- tablet
- composition
- coated
- immediate release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
resumo composição de liberação imediata de sovaprevir, composição de sovaprevir de 200 mg, núcleo de comprimido de sovaprevir e comprimido de sovaprevir revestido a divulgação inclui núcleos de comprimido compreendendo sovaprevir e um inibidor de crescimento de cristal selecionado a partir de hidroxipropilmetilcelulose (hpmc), hpc (hidroxipropilcelulose), succinato de acetato de hipromelose (hpmcas), polivinil pirrolidona (pvp), copovidona (pvp-va), um copolímero de ácido metacrílico e acrilato de etila, ou qualquer combinação destes anteriormente mencionados, em que a proporção de sovaprevir para o inibidor do crescimento de cristal é de aproximadamente 40:60 (p/p) a aproximadamente 60:40 (p/p). a divulgação inclui ainda comprimidos revestidos. a divulgação também inclui métodos para o tratamento de hcv com os comprimidos descritos no presente documento. 1/1
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361790645P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/025969 WO2014151547A1 (en) | 2013-03-15 | 2014-03-13 | Sovaprevir tablets |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015023381A2 true BR112015023381A2 (pt) | 2017-07-18 |
Family
ID=50439520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015023381A BR112015023381A2 (pt) | 2013-03-15 | 2014-03-13 | composição de liberação imediata de sovaprevir, composição de sovaprevir de 200 mg, núcleo de comprimido de sovaprevir e comprimido de sovaprevir revestido |
Country Status (12)
Country | Link |
---|---|
US (1) | US20140271855A1 (pt) |
EP (1) | EP2968171A1 (pt) |
JP (1) | JP2016512845A (pt) |
KR (1) | KR20160005022A (pt) |
CN (1) | CN105358137A (pt) |
AU (1) | AU2014233897A1 (pt) |
BR (1) | BR112015023381A2 (pt) |
CA (1) | CA2905423A1 (pt) |
EA (1) | EA201591787A1 (pt) |
IL (1) | IL241350A0 (pt) |
SG (1) | SG11201507468TA (pt) |
WO (1) | WO2014151547A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0714343A2 (pt) | 2006-07-13 | 2013-03-19 | Achillion Pharmaceuticals Inc | peptÍdeos de 4-amino-4-oxobutanoil como inibidores de replicaÇço viral |
US9227952B2 (en) | 2013-03-15 | 2016-01-05 | Achillion Pharmaceuticals, Inc. | Sovaprevir polymorphs and methods of manufacture thereof |
CN104258411A (zh) * | 2014-09-19 | 2015-01-07 | 安徽山河药用辅料股份有限公司 | 一种硅化微晶纤维素复合辅料及其制备方法 |
CN105943536A (zh) * | 2016-05-06 | 2016-09-21 | 杭州容立医药科技有限公司 | 一种固体分散体的制备方法及其应用 |
EP3860849A4 (en) * | 2018-10-05 | 2022-06-22 | ISP Investments LLC | SMOOTH HIGH SOLIDS FILM COATING COMPOSITION COMPRISING WATER-SOLUBLE CELLULOSE ETHER, AND METHOD FOR PREPARING THE SAME |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101506223B (zh) * | 2006-07-13 | 2013-05-22 | 艾其林医药公司 | 作为病毒复制抑制剂的4-氨基-4-氧代丁酰基肽 |
JP2011530532A (ja) * | 2008-08-07 | 2011-12-22 | シェーリング コーポレイション | 固体分子分散物中のhcvプロテアーゼインヒビターの薬学的処方物 |
US8927576B2 (en) * | 2009-04-06 | 2015-01-06 | PTC Therpeutics, Inc. | HCV inhibitor and therapeutic agent combinations |
JP5781706B2 (ja) * | 2011-12-29 | 2015-09-24 | アッヴィ・アイルランド・アンリミテッド・カンパニー | Hcv阻害剤を含む固体組成物 |
WO2013116592A1 (en) * | 2012-02-01 | 2013-08-08 | Kadmon Pharmaceuticals, Llc | Once daily treatment of hepatitis c with ribavirin and taribavirin |
-
2014
- 2014-03-13 KR KR1020157028999A patent/KR20160005022A/ko not_active Application Discontinuation
- 2014-03-13 WO PCT/US2014/025969 patent/WO2014151547A1/en active Application Filing
- 2014-03-13 SG SG11201507468TA patent/SG11201507468TA/en unknown
- 2014-03-13 EP EP14715515.4A patent/EP2968171A1/en not_active Withdrawn
- 2014-03-13 CN CN201480028573.3A patent/CN105358137A/zh active Pending
- 2014-03-13 BR BR112015023381A patent/BR112015023381A2/pt not_active IP Right Cessation
- 2014-03-13 CA CA2905423A patent/CA2905423A1/en not_active Abandoned
- 2014-03-13 US US14/208,195 patent/US20140271855A1/en not_active Abandoned
- 2014-03-13 EA EA201591787A patent/EA201591787A1/ru unknown
- 2014-03-13 JP JP2016502012A patent/JP2016512845A/ja active Pending
- 2014-03-13 AU AU2014233897A patent/AU2014233897A1/en not_active Abandoned
-
2015
- 2015-09-09 IL IL241350A patent/IL241350A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP2968171A1 (en) | 2016-01-20 |
IL241350A0 (en) | 2015-11-30 |
EA201591787A1 (ru) | 2015-12-30 |
JP2016512845A (ja) | 2016-05-09 |
CN105358137A (zh) | 2016-02-24 |
AU2014233897A1 (en) | 2015-10-01 |
KR20160005022A (ko) | 2016-01-13 |
WO2014151547A1 (en) | 2014-09-25 |
SG11201507468TA (en) | 2015-10-29 |
CA2905423A1 (en) | 2014-09-25 |
US20140271855A1 (en) | 2014-09-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |