BR112015010756A2 - vacina de emergência baseada em peptídeo sintético contra doença do pé-e-boca (fmd) - Google Patents
vacina de emergência baseada em peptídeo sintético contra doença do pé-e-boca (fmd)Info
- Publication number
- BR112015010756A2 BR112015010756A2 BR112015010756A BR112015010756A BR112015010756A2 BR 112015010756 A2 BR112015010756 A2 BR 112015010756A2 BR 112015010756 A BR112015010756 A BR 112015010756A BR 112015010756 A BR112015010756 A BR 112015010756A BR 112015010756 A2 BR112015010756 A2 BR 112015010756A2
- Authority
- BR
- Brazil
- Prior art keywords
- fmd
- synthetic peptide
- mouth disease
- vaccine against
- based emergency
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/135—Foot- and mouth-disease virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
- C12N2770/32134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2012/065386 WO2014077825A1 (en) | 2012-11-16 | 2012-11-16 | Synthetic peptide-based emergency vaccine against foot and mouth disease (fmd) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112015010756A2 true BR112015010756A2 (pt) | 2017-08-22 |
| BR112015010756A8 BR112015010756A8 (pt) | 2018-01-16 |
| BR112015010756B1 BR112015010756B1 (pt) | 2022-04-12 |
Family
ID=50731571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015010756-7A BR112015010756B1 (pt) | 2012-11-16 | 2012-11-16 | Composições de vacina para a doença do pé-e-boca (fmd),e uso das mesmas |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10420832B2 (pt) |
| EP (2) | EP2919808B1 (pt) |
| JP (1) | JP2016501850A (pt) |
| CN (1) | CN104244973B (pt) |
| AU (2) | AU2012394394A1 (pt) |
| BR (1) | BR112015010756B1 (pt) |
| CA (1) | CA2890678C (pt) |
| HU (1) | HUE051277T2 (pt) |
| IN (1) | IN2015DN03931A (pt) |
| MX (1) | MX2015006170A (pt) |
| TW (1) | TWI620574B (pt) |
| WO (1) | WO2014077825A1 (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104162152A (zh) * | 2013-05-16 | 2014-11-26 | 申联生物医药（上海）有限公司 | 猪口蹄疫o型合成肽疫苗及其制备方法 |
| CA2924526A1 (en) | 2013-09-19 | 2015-03-26 | Paul Joseph Dominowski | Water-in-oil emulsions comprising immunostimulatory oligonucleotides |
| PL3244920T3 (pl) * | 2015-01-16 | 2023-09-25 | Zoetis Services Llc | Szczepionka przeciw pryszczycy |
| CN104672312B (zh) * | 2015-03-20 | 2019-03-19 | 中牧实业股份有限公司 | 牛口蹄疫a型多肽疫苗 |
| CN105418738B (zh) * | 2015-07-03 | 2019-04-19 | 申联生物医药（上海）有限公司 | 口蹄疫病毒a型抗原多肽、融合抗原多肽及疫苗 |
| KR20180069081A (ko) * | 2015-11-11 | 2018-06-22 | 인트렉손 코포레이션 | 심장 이상 및 기타 병리 이상의 치료를 위한 복수의 생물학적으로 활성화된 폴리펩티드를 단일 벡터로부터 발현하기 위한 조성물 및 방법 |
| BR112018075033A2 (pt) | 2016-06-02 | 2019-03-26 | Zoetis Services Llc | vacina contra bronquite infecciosa |
| CN106421776A (zh) * | 2016-08-31 | 2017-02-22 | 天津瑞普生物技术股份有限公司 | 一种可增强口蹄疫亚单位疫苗免疫效力的t细胞表位合成肽佐剂 |
| US10172933B2 (en) | 2016-10-31 | 2019-01-08 | The United States Of America, As Represented By The Secretary Of Agriculture | Mosaic vaccines for serotype a foot-and-mouth disease virus |
| JP7174492B2 (ja) * | 2017-01-04 | 2022-11-17 | ウォルグ ファーマシューティカルズ （ハンジョウ） カンパニー，リミテッド | Ｓ－アレスチンペプチドおよびその治療的使用 |
| CN106986925B (zh) * | 2017-05-08 | 2020-08-25 | 中牧实业股份有限公司 | 牛口蹄疫o型、a型二价合成肽疫苗及其制备方法和应用 |
| CN107365367A (zh) * | 2017-08-16 | 2017-11-21 | 山东省农业科学院奶牛研究中心 | A型口蹄疫病毒vp1蛋白抗原表位基因多肽及其应用 |
| EP3909970A1 (en) * | 2020-05-14 | 2021-11-17 | Consejo Superior De Investigaciones Científicas | Peptide vaccines for the prevention of foot-and-mouth disease |
| CN117304277B (zh) * | 2023-09-26 | 2024-03-08 | 中国农业科学院兰州兽医研究所 | 一种o型口蹄疫病毒vp4蛋白t细胞表位多肽及其应用 |
| CN117304271B (zh) * | 2023-09-27 | 2024-04-16 | 中国农业科学院兰州兽医研究所 | 一种o型口蹄疫病毒vp2蛋白t细胞表位多肽及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1983003547A1 (en) | 1982-04-14 | 1983-10-27 | Bittle, James, L. | Synthetic picornavirus antigen |
| US4732971A (en) | 1985-06-03 | 1988-03-22 | Eli Lilly And Company | Synthetic vaccines for foot and mouth disease |
| US5476765A (en) | 1987-01-09 | 1995-12-19 | United Biomedical, Inc. | Synthetic peptide compositions with immunoreactivities to antibodies to HTLV and as vaccines |
| US5864008A (en) * | 1988-03-25 | 1999-01-26 | James; Stephen | Peptides derived from foot-and-mouth disease virus, pharmaceutical compositions, and methods for using the peptides |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| GB8920357D0 (en) | 1989-09-08 | 1989-10-25 | Wellcome Found | Peptides |
| US5106726A (en) | 1990-02-16 | 1992-04-21 | United Biomedical, Inc. | Synthetic peptides specific for the detection of antibodies to HCV |
| DE69332602T2 (de) * | 1992-10-14 | 2003-11-13 | Sagem | Modem enthaltender Fernsprecher |
| JP3795914B2 (ja) | 1993-04-27 | 2006-07-12 | ユナイテッド・バイオメディカル・インコーポレイテッド | ワクチン用免疫原性ｌｈｒｈペプチド構築体および合成普遍免疫刺激器 |
| US5759551A (en) | 1993-04-27 | 1998-06-02 | United Biomedical, Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
| EP0725838A4 (en) | 1993-10-26 | 1997-02-26 | United Biomedical Inc | STRUCTURED SYNTHETIC ANTIGAN BANKS AS DIAGNOSTICS, VACCINE AND THERAPEUTIC AGENTS |
| FR2736642B1 (fr) | 1995-07-10 | 1997-09-12 | Pasteur Institut | Immunovecteurs, notamment anticorps et fragments d'anticorps utilisables pour le transport intracellulaire et intranucleaire de principes biologiquement actifs notamment d'haptenes, de proteines et d'acides nucleiques |
| US6107021A (en) | 1998-06-20 | 2000-08-22 | United Biomedical, Inc. | Synthetic peptide vaccines for foot-and-mouth disease |
| TWI229679B (en) * | 1998-06-20 | 2005-03-21 | United Biomedical Inc | Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens |
| US8088388B2 (en) | 2002-02-14 | 2012-01-03 | United Biomedical, Inc. | Stabilized synthetic immunogen delivery system |
| DK1543039T3 (da) * | 2002-08-12 | 2011-10-31 | Queensland Inst Med Res | Nye immunogene lipopeptider omfattende T-hjælper- og B-celle-epitoper |
| CN102168088B (zh) * | 2010-12-23 | 2012-12-26 | 中国农业科学院兰州兽医研究所 | T细胞免疫原基因ti及其在口蹄疫蛋白亚单位疫苗和灭活疫苗中的应用 |
-
2012
- 2012-11-16 US US14/443,363 patent/US10420832B2/en active Active
- 2012-11-16 WO PCT/US2012/065386 patent/WO2014077825A1/en active Application Filing
- 2012-11-16 CA CA2890678A patent/CA2890678C/en active Active
- 2012-11-16 MX MX2015006170A patent/MX2015006170A/es unknown
- 2012-11-16 AU AU2012394394A patent/AU2012394394A1/en not_active Abandoned
- 2012-11-16 JP JP2015543013A patent/JP2016501850A/ja active Pending
- 2012-11-16 EP EP12888444.2A patent/EP2919808B1/en active Active
- 2012-11-16 EP EP20187920.2A patent/EP3777886A1/en not_active Withdrawn
- 2012-11-16 BR BR112015010756-7A patent/BR112015010756B1/pt active IP Right Grant
- 2012-11-16 CN CN201280071993.0A patent/CN104244973B/zh active Active
- 2012-11-16 HU HUE12888444A patent/HUE051277T2/hu unknown
-
2013
- 2013-11-01 TW TW102139710A patent/TWI620574B/zh not_active IP Right Cessation
-
2015
- 2015-05-08 IN IN3931DEN2015 patent/IN2015DN03931A/en unknown
-
2018
- 2018-09-20 AU AU2018232999A patent/AU2018232999B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US10420832B2 (en) | 2019-09-24 |
| US20150306203A1 (en) | 2015-10-29 |
| WO2014077825A1 (en) | 2014-05-22 |
| TWI620574B (zh) | 2018-04-11 |
| CN104244973B (zh) | 2017-10-20 |
| HUE051277T2 (hu) | 2021-03-01 |
| JP2016501850A (ja) | 2016-01-21 |
| EP3777886A1 (en) | 2021-02-17 |
| MX2015006170A (es) | 2015-08-07 |
| AU2018232999B2 (en) | 2020-02-27 |
| BR112015010756B1 (pt) | 2022-04-12 |
| EP2919808B1 (en) | 2020-07-29 |
| AU2018232999A1 (en) | 2018-10-11 |
| IN2015DN03931A (pt) | 2015-10-02 |
| CA2890678A1 (en) | 2014-05-22 |
| CA2890678C (en) | 2022-02-22 |
| CN104244973A (zh) | 2014-12-24 |
| EP2919808A4 (en) | 2016-10-12 |
| BR112015010756A8 (pt) | 2018-01-16 |
| TW201420114A (zh) | 2014-06-01 |
| EP2919808A1 (en) | 2015-09-23 |
| AU2012394394A1 (en) | 2015-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
| B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/11/2012, OBSERVADAS AS CONDICOES LEGAIS. |