BR112014029705A2 - composto ou sal, medicamento, métodos para inibir quinase de janus em um mamífero, e para a profilaxia ou tratamento de doenças autoimunes, e, uso de um composto ou sal - Google Patents

composto ou sal, medicamento, métodos para inibir quinase de janus em um mamífero, e para a profilaxia ou tratamento de doenças autoimunes, e, uso de um composto ou sal

Info

Publication number
BR112014029705A2
BR112014029705A2 BR112014029705A BR112014029705A BR112014029705A2 BR 112014029705 A2 BR112014029705 A2 BR 112014029705A2 BR 112014029705 A BR112014029705 A BR 112014029705A BR 112014029705 A BR112014029705 A BR 112014029705A BR 112014029705 A2 BR112014029705 A2 BR 112014029705A2
Authority
BR
Brazil
Prior art keywords
salt
compound
prophylaxis
mammal
medicament
Prior art date
Application number
BR112014029705A
Other languages
English (en)
Inventor
Kaieda Akira
Kikuchi Fumiaki
Nara Hiroshi
Daini Masaki
Kamei Taku
Imaeda Toshihiro
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of BR112014029705A2 publication Critical patent/BR112014029705A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
BR112014029705A 2012-06-01 2013-05-31 composto ou sal, medicamento, métodos para inibir quinase de janus em um mamífero, e para a profilaxia ou tratamento de doenças autoimunes, e, uso de um composto ou sal BR112014029705A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012126462 2012-06-01
PCT/JP2013/065183 WO2013180265A1 (ja) 2012-06-01 2013-05-31 複素環化合物

Publications (1)

Publication Number Publication Date
BR112014029705A2 true BR112014029705A2 (pt) 2017-06-27

Family

ID=49673448

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014029705A BR112014029705A2 (pt) 2012-06-01 2013-05-31 composto ou sal, medicamento, métodos para inibir quinase de janus em um mamífero, e para a profilaxia ou tratamento de doenças autoimunes, e, uso de um composto ou sal

Country Status (8)

Country Link
US (2) US9371320B2 (pt)
EP (1) EP2857400A4 (pt)
JP (1) JPWO2013180265A1 (pt)
CN (1) CN104507940B (pt)
BR (1) BR112014029705A2 (pt)
CA (1) CA2874987A1 (pt)
EA (1) EA201492250A1 (pt)
WO (1) WO2013180265A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10059705B2 (en) 2013-03-19 2018-08-28 Merck Sharp & Dohme Corp. Acyclic cyanoethylpyrazolo pyridones as janus kinase inhibitors
WO2014146249A1 (en) * 2013-03-19 2014-09-25 Merck Sharp & Dohme Corp. Geminally substituted cyanoethylpyrazolo pyridones as janus kinase inhibitors
CN105189508B (zh) * 2013-03-19 2018-11-23 默沙东公司 作为janus激酶抑制剂的环烷基腈吡唑并吡啶酮
WO2014146246A1 (en) 2013-03-19 2014-09-25 Merck Sharp & Dohme Corp. Cycloalkyl nitrile pyrazolo pyridones as janus kinase inhibitors
KR20150130311A (ko) * 2013-03-19 2015-11-23 머크 샤프 앤드 돔 코포레이션 야누스 키나제 억제제로서의 n-(2-시아노 헤테로시클릴)피라졸로 피리돈
EP2980089B1 (en) * 2013-03-28 2017-12-20 Takeda Pharmaceutical Company Limited Heterocyclic compound
WO2019073253A1 (en) 2017-10-13 2019-04-18 Imperial Innovations Limited INHIBITORS OF MAP4K4
KR102094802B1 (ko) * 2017-10-24 2020-03-31 고려대학교 산학협력단 소변 대사체 분석을 이용한 베체트병의 진단방법
CN110343103A (zh) * 2019-07-04 2019-10-18 深圳市格物致欣化学技术有限公司 吡唑并吡啶类化合物及其制备方法
BR112023016590A2 (pt) 2021-02-19 2023-11-14 Sudo Biosciences Ltd Inibidores de tyk2 e seus usos
CN113671064B (zh) * 2021-07-15 2022-05-17 中国海洋大学 一种定量分析血浆中氨来占诺的血药浓度的检测方法

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
US3663559A (en) 1969-12-03 1972-05-16 Union Carbide Corp Preparation of oxo-furo-pyridines from furylvinyl isocyanates
JPS5814437B2 (ja) 1975-12-25 1983-03-18 タイホウヤクヒンコウギヨウ カブシキガイシヤ ピラゾロピリジン −３− カルボンサンユウドウタイノセイゾウホウ
JPS5814438B2 (ja) * 1975-12-27 1983-03-18 タイホウヤクヒンコウギヨウ カブシキガイシヤ ピラゾロピリジンユウドウタイノ セイゾウホウホウ
JP2759227B2 (ja) 1990-09-28 1998-05-28 大鵬薬品工業株式会社 ピラゾロピリジン誘導体
CZ20014244A3 (cs) 1999-06-03 2002-07-17 Knoll Gmbh Benzotiazinonové a benzoxazinonové sloučeniny
AU2003241925A1 (en) 2002-05-31 2003-12-19 Eisai R&D Management Co., Ltd. Pyrazole compound and medicinal composition containing the same
UY28103A1 (es) * 2002-12-03 2004-06-30 Boehringer Ingelheim Pharma Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos
AR045595A1 (es) 2003-09-04 2005-11-02 Vertex Pharma Composiciones utiles como inhibidores de proteinas quinasas
WO2006003440A1 (en) * 2004-07-05 2006-01-12 Astex Therapeutics Limited 3,4-disubstituted pyrazoles as cyclin dependent kinases (cdk) or aurora kinase or glycogen synthase 3 (gsk-3) inhibitors
CA2609582A1 (en) 2005-06-14 2006-12-28 Schering Corporation Aspartyl protease inhibitors
WO2007115231A2 (en) 2006-03-30 2007-10-11 Chemocentryx, Inc. Cxcr4 modulators
WO2008047831A1 (fr) 2006-10-17 2008-04-24 Kyowa Hakko Kirin Co., Ltd. Inhibiteurs de JAK
US8658637B2 (en) 2006-12-06 2014-02-25 Boehringer Ingelheim International Gmbh Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
AR077033A1 (es) 2009-06-11 2011-07-27 Hoffmann La Roche Compuestos inhibidores de las quinasas de janus y su uso en el tratamiento de enfermedades inmunologicas
WO2012030924A1 (en) * 2010-09-01 2012-03-08 Ambit Biosciences Corporation Azolopyridine and azolopyrimidine compounds and methods of use thereof
WO2013125543A1 (ja) 2012-02-20 2013-08-29 武田薬品工業株式会社 複素環化合物
WO2014146246A1 (en) * 2013-03-19 2014-09-25 Merck Sharp & Dohme Corp. Cycloalkyl nitrile pyrazolo pyridones as janus kinase inhibitors

Also Published As

Publication number Publication date
US9371320B2 (en) 2016-06-21
US20150141406A1 (en) 2015-05-21
WO2013180265A1 (ja) 2013-12-05
EP2857400A4 (en) 2015-12-09
EA201492250A1 (ru) 2015-08-31
CN104507940B (zh) 2017-01-25
JPWO2013180265A1 (ja) 2016-01-21
CN104507940A (zh) 2015-04-08
CA2874987A1 (en) 2013-12-05
US20160251352A1 (en) 2016-09-01
EP2857400A1 (en) 2015-04-08

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B06I Technical and formal requirements: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B08F Application fees: dismissal - article 86 of industrial property law
B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2465 DE 03-04-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.