BR112014026199A2 - processo de fermentação - Google Patents

processo de fermentação

Info

Publication number
BR112014026199A2
BR112014026199A2 BR112014026199A BR112014026199A BR112014026199A2 BR 112014026199 A2 BR112014026199 A2 BR 112014026199A2 BR 112014026199 A BR112014026199 A BR 112014026199A BR 112014026199 A BR112014026199 A BR 112014026199A BR 112014026199 A2 BR112014026199 A2 BR 112014026199A2
Authority
BR
Brazil
Prior art keywords
fermentation
hydrocyclone
organic acid
solid
broth
Prior art date
Application number
BR112014026199A
Other languages
English (en)
Other versions
BR112014026199B1 (pt
Inventor
Dirk Kon Adriaan
Banier De Haan Andre
Gerrit Jan Kool Frederik
Van Krieken Jan
Original Assignee
Purac Biochem Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purac Biochem Bv filed Critical Purac Biochem Bv
Publication of BR112014026199A2 publication Critical patent/BR112014026199A2/pt
Publication of BR112014026199B1 publication Critical patent/BR112014026199B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/48—Tricarboxylic acids, e.g. citric acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/50—Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/52—Propionic acid; Butyric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/54—Acetic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/267—Separation of sediment aided by centrifugal force or centripetal force by using a cyclone
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Abstract

resumo patente de invenção: "processo de fermentação". a presente invenção refere-se a um processo de fermentação para a produção de um sal de ácido orgânico que compreende as etapas de - fermentar um microrganismo em um meio de fermentação em um reator de fermentação para formar um caldo de fermentação que compreende um sal de ácido orgânico, em que parte do sal de ácido orgânico está presente no estado sólido e parte do sal de ácido orgânico é dissolvida no caldo de fermentação; - retirar pelo menos parte do caldo de fermentação do reator de fermentação, fornecer o dito caldo a um hidrociclone, e retirar um efluente superior e um efluente inferior do hidrociclone; - fornecer o efluente inferior do hidrociclone a uma etapa de separação de sólido/líquido, para formar uma fração sólida e uma fração líquida, - fornecer pelo menos 30% em vol. do total do efluente superior do hidrociclone e da fração líquida da etapa de separação de sólido-líquido ao reator de fermentação. o processo de acordo com a invenção é ao mesmo tempo estável, fornece um produto com propriedades satisfatórias, e fornece um alto rendimento de processo, especialmente atraente em uma escala industrial. 18/19 22791828v1 3/3 1/3 1/1 1/1
BR112014026199-7A 2012-04-25 2013-04-24 Processo de fermentação BR112014026199B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261637867P 2012-04-25 2012-04-25
EP12165513 2012-04-25
US61/637,867 2012-04-25
EP12165513.8 2012-04-25
PCT/EP2013/058500 WO2013160352A1 (en) 2012-04-25 2013-04-24 Fermentation process

Publications (2)

Publication Number Publication Date
BR112014026199A2 true BR112014026199A2 (pt) 2017-06-27
BR112014026199B1 BR112014026199B1 (pt) 2021-06-29

Family

ID=49482232

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014026199-7A BR112014026199B1 (pt) 2012-04-25 2013-04-24 Processo de fermentação

Country Status (9)

Country Link
US (1) US9644218B2 (pt)
EP (1) EP2841583B1 (pt)
JP (1) JP5953425B2 (pt)
CN (2) CN106906252B (pt)
BR (1) BR112014026199B1 (pt)
ES (1) ES2577052T3 (pt)
HU (1) HUE029321T2 (pt)
PL (1) PL2841583T3 (pt)
WO (1) WO2013160352A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2016015894A (es) * 2014-06-06 2017-03-20 Purac Biochem Bv Procedimiento de fermentacion a base de glicerol.
CA2979587C (en) * 2015-03-17 2020-03-24 Purac Biochem Bv Method for manufacturing furan-2,5-dicarboxylic acid (fdca) from a solid salt
CA3019265C (en) * 2016-04-12 2022-03-08 Purac Biochem Bv Magnesium lactate fermentation process
MY188628A (en) 2016-05-30 2021-12-22 Purac Biochem Bv Method for separating biomass from solid fermentation product
GB201610932D0 (en) * 2016-06-22 2016-08-03 Univ Of Manchester The Improvements in and relating to lipid production
UA125439C2 (uk) * 2016-11-29 2022-03-09 Пурак Біокем Бв Процес виробництва продукту ферментації
CN108008096B (zh) * 2017-12-15 2023-12-12 苏州酒花网络科技有限公司 浮动式发酵状态检测装置及检测方法
DE102021004122A1 (de) * 2021-08-11 2023-02-16 Bta International Gmbh Verfahren und Vorrichtung zur hydrodynamischen Schwerstoffabtrennung mit hohem Wirkungsgrad

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK188889A (da) * 1988-04-20 1989-10-23 Bioteknika International Fremgangsmaade til fremstilling af threonin og andre homoserinderivater samt celle som kan gennemfoere methioninudnyttelsesvejen og kan udtrykke s-adenosylmethioninhydrolase
JP2958789B2 (ja) * 1990-01-22 1999-10-06 味の素株式会社 アミノ酸・核酸およびその誘導体の精製方法
US5236590A (en) * 1991-11-21 1993-08-17 Chevron Research And Technology Company Process for removing dissolved organics from aqueous compositions
HU222511B1 (hu) * 1994-12-07 2003-08-28 Controlled Environmental Systems Corporation Eljárás tejsav előállítására szilárd hulladékból
UA43879C2 (uk) * 1994-12-07 2002-01-15 Кентроулд Інвайєронментал Сістемз Корпорейшн Спосіб одержання молочної кислоти з міських твердих відходів (варіанти) та спосіб одержання молочної кислоти з целюлозного компонента міських твердих відходів
JP4427450B2 (ja) * 2002-10-22 2010-03-10 プラク・ビオヘム・ベー・ブイ 乳酸含有発酵生成物からバイオマスを凝集で分離
CN101018756B (zh) 2004-06-17 2011-06-08 普拉克生化公司 由含乳酸镁的介质制备乳酸或乳酸盐的方法
JP5566028B2 (ja) 2006-01-11 2014-08-06 ディーエスエム アイピー アセッツ ビー．ブイ． 有機アミンの単離方法
BRPI0907475B1 (pt) * 2008-02-08 2019-04-24 Purac Biochem B.V. Misturador do tipo de vórtice e método de obtenção de uma solução ou pasta fluida supersaturada
EP2370586B1 (en) 2008-12-02 2017-11-01 PURAC Biochem BV Process for the preparation of a monovalent succinate salt
KR101809891B1 (ko) 2010-02-08 2017-12-20 푸락 바이오켐 비.브이. 락트산의 제조방법
EP2360137B1 (en) 2010-02-12 2013-08-07 PURAC Biochem BV Process for manufacturing succinic acid
EP2582826A2 (en) * 2010-06-18 2013-04-24 Butamax(tm) Advanced Biofuels LLC Production of alcohol esters and in situ product removal during alcohol fermentation

Also Published As

Publication number Publication date
EP2841583B1 (en) 2016-04-06
JP2015514432A (ja) 2015-05-21
HUE029321T2 (en) 2017-02-28
PL2841583T3 (pl) 2016-12-30
US20150079647A1 (en) 2015-03-19
JP5953425B2 (ja) 2016-07-20
BR112014026199B1 (pt) 2021-06-29
EP2841583A1 (en) 2015-03-04
CN106906252A (zh) 2017-06-30
CN104271753A (zh) 2015-01-07
ES2577052T3 (es) 2016-07-12
WO2013160352A1 (en) 2013-10-31
US9644218B2 (en) 2017-05-09
CN104271753B (zh) 2017-04-05
CN106906252B (zh) 2021-01-15

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/04/2013, OBSERVADAS AS CONDICOES LEGAIS.