BR112014025507A2 - formulação vesicular e método de tratamento - Google Patents

formulação vesicular e método de tratamento

Info

Publication number
BR112014025507A2
BR112014025507A2 BR112014025507A BR112014025507A BR112014025507A2 BR 112014025507 A2 BR112014025507 A2 BR 112014025507A2 BR 112014025507 A BR112014025507 A BR 112014025507A BR 112014025507 A BR112014025507 A BR 112014025507A BR 112014025507 A2 BR112014025507 A2 BR 112014025507A2
Authority
BR
Brazil
Prior art keywords
treatment method
vesicular formulation
vesicular
formulation
treatment
Prior art date
Application number
BR112014025507A
Other languages
English (en)
Other versions
BR112014025507B1 (pt
Inventor
earl Michael
Baverstock Nicholas
Wolf Garraway Richard
Yurdakul Saruhan
Original Assignee
Sequessome Tech Holdings Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sequessome Tech Holdings Limited filed Critical Sequessome Tech Holdings Limited
Publication of BR112014025507A2 publication Critical patent/BR112014025507A2/pt
Publication of BR112014025507B1 publication Critical patent/BR112014025507B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/688Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
BR112014025507-5A 2012-04-12 2013-04-12 Uso de uma formulação vesicular BR112014025507B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1206486.1 2012-04-12
GBGB1206486.1A GB201206486D0 (en) 2012-04-12 2012-04-12 Vesicular formulations and uses thereof
PCT/EP2013/057742 WO2013153221A1 (en) 2012-04-12 2013-04-12 Vesicular formulations for use in the treatment of pain or reduced mobility of a joint

Publications (2)

Publication Number Publication Date
BR112014025507A2 true BR112014025507A2 (pt) 2017-08-08
BR112014025507B1 BR112014025507B1 (pt) 2022-01-04

Family

ID=46208989

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014025507-5A BR112014025507B1 (pt) 2012-04-12 2013-04-12 Uso de uma formulação vesicular

Country Status (26)

Country Link
US (3) US20150065461A1 (pt)
EP (1) EP2836203B1 (pt)
JP (1) JP2015512926A (pt)
KR (1) KR102204725B1 (pt)
CN (1) CN104363894B (pt)
AU (1) AU2013246822A1 (pt)
BR (1) BR112014025507B1 (pt)
CA (1) CA2870111A1 (pt)
CL (1) CL2014002706A1 (pt)
CO (1) CO7141430A2 (pt)
DK (1) DK2836203T3 (pt)
EA (1) EA039626B1 (pt)
ES (1) ES2916803T3 (pt)
GB (2) GB201206486D0 (pt)
HR (1) HRP20220700T1 (pt)
HU (1) HUE058972T2 (pt)
IL (1) IL234862A0 (pt)
IN (1) IN2014DN08259A (pt)
LT (1) LT2836203T (pt)
MX (1) MX2014012198A (pt)
PH (1) PH12014502079A1 (pt)
PL (1) PL2836203T3 (pt)
PT (1) PT2836203T (pt)
SG (1) SG11201406251VA (pt)
SI (1) SI2836203T1 (pt)
WO (1) WO2013153221A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100255080A1 (en) * 2009-04-02 2010-10-07 Sesvalia Usa, Llc Liposomal ALA pharmaceutical and cosmeceutical compositions and methods of treatment
CN102770162B (zh) 2009-08-21 2016-09-28 靶向递送技术有限公司 囊泡制剂
GB201205642D0 (en) 2012-03-29 2012-05-16 Sequessome Technology Holdings Ltd Vesicular formulations
GB201505532D0 (en) * 2015-03-31 2015-05-13 Sequessome Technology Holdings Ltd Formulations
ES2895910T3 (es) 2015-06-30 2022-02-23 Sequessome Tech Holdings Limited Composiciones multifásicas
WO2019038763A1 (en) * 2017-08-22 2019-02-28 Moebius Medical Ltd. LIPOSOMAL FORMULATION FOR JOINT LUBRICATION
US20190083386A1 (en) 2017-09-15 2019-03-21 Ampersand Biopharmaceuticals, Inc. Methods and formulations for transdermal administration of buffering agents
CN110314137B (zh) * 2018-03-30 2022-04-05 北京泰德制药股份有限公司 一种含有脂质囊泡的冻干制剂
KR20230041954A (ko) 2021-09-17 2023-03-27 서울대학교산학협력단 골관절염 예방 또는 치료용 약학 조성물 및 건강기능식품

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4327193A (en) * 1992-07-08 1994-01-31 Dianorm-Gerate G. Maierhofer Liposomes, method of preparing them and their use in the preparation of drugs
AUPN723395A0 (en) * 1995-12-19 1996-01-18 Macnaught Medical Pty Limited Lubrication methods
CZ20033241A3 (cs) * 2001-05-31 2004-08-18 Pharmaciaácorporation Kůži prostupující přípravek obsahující selektivně inhibující cyklooxygenázu@@ a jednosytný alkohol
JP2004535434A (ja) * 2001-06-25 2004-11-25 デピユイ 関節炎にかかった関節の処置のためのグリコサミノグリカン類のリポソームカプセル化
US7115666B2 (en) * 2002-10-15 2006-10-03 Renovis, Inc. Nitrone compounds, pharmaceutical compositions containing the same and methods for treating inflammation and neuropathic pain
ES2599630T3 (es) * 2006-09-28 2017-02-02 Hadasit Medical Research Services & Development Limited Uso de glicerofosfolípidos para lubricación de las articulaciones
CN105434354A (zh) * 2009-06-03 2016-03-30 斯昆申技术控股有限责任公司 用于治疗深部组织疼痛的制剂
CN102770162B (zh) * 2009-08-21 2016-09-28 靶向递送技术有限公司 囊泡制剂
JP6453781B2 (ja) * 2013-03-13 2019-01-16 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft ヒトpi3kca(pik3ca)遺伝子変異検出のための方法及び組成物

Also Published As

Publication number Publication date
HRP20220700T1 (hr) 2022-07-08
EP2836203B1 (en) 2022-03-09
BR112014025507B1 (pt) 2022-01-04
CO7141430A2 (es) 2014-12-12
US20210393655A1 (en) 2021-12-23
KR20150008869A (ko) 2015-01-23
CN104363894A (zh) 2015-02-18
GB2515439A (en) 2014-12-24
IL234862A0 (en) 2014-12-31
EP2836203A1 (en) 2015-02-18
EA039626B1 (ru) 2022-02-17
SI2836203T1 (sl) 2022-07-29
DK2836203T3 (da) 2022-06-07
CN104363894B (zh) 2016-11-23
LT2836203T (lt) 2022-06-10
GB201206486D0 (en) 2012-05-30
PH12014502079A1 (en) 2014-12-10
WO2013153221A1 (en) 2013-10-17
AU2013246822A1 (en) 2014-10-16
GB2515439B (en) 2017-08-23
SG11201406251VA (en) 2014-10-30
EA201491583A1 (ru) 2015-05-29
ES2916803T3 (es) 2022-07-06
GB201419074D0 (en) 2014-12-10
US20170128473A1 (en) 2017-05-11
JP2015512926A (ja) 2015-04-30
KR102204725B1 (ko) 2021-01-19
PL2836203T3 (pl) 2022-07-11
IN2014DN08259A (pt) 2015-05-15
CA2870111A1 (en) 2013-10-17
HUE058972T2 (hu) 2022-09-28
US20150065461A1 (en) 2015-03-05
CL2014002706A1 (es) 2015-04-24
PT2836203T (pt) 2022-06-15
MX2014012198A (es) 2015-06-04

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 12/04/2013, OBSERVADAS AS CONDICOES LEGAIS.