BR112014023913A2 - - Google Patents

Info

Publication number
BR112014023913A2
BR112014023913A2 BR112014023913A BR112014023913A BR112014023913A2 BR 112014023913 A2 BR112014023913 A2 BR 112014023913A2 BR 112014023913 A BR112014023913 A BR 112014023913A BR 112014023913 A BR112014023913 A BR 112014023913A BR 112014023913 A2 BR112014023913 A2 BR 112014023913A2
Authority
BR
Brazil
Application number
BR112014023913A
Other versions
BR112014023913B1 (pt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR112014023913A2 publication Critical patent/BR112014023913A2/pt
Publication of BR112014023913B1 publication Critical patent/BR112014023913B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01DNA viruses
    • G01N2333/03Herpetoviridae, e.g. pseudorabies virus
    • G01N2333/04Varicella-zoster virus
    • G01N2333/045Cytomegalovirus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms
BR112014023913-4A 2012-03-27 2013-03-27 Métodos para detecção de anticorpos neutralizantes de anticitomegalovírus BR112014023913B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261616204P 2012-03-27 2012-03-27
US61/616,204 2012-03-27
PCT/IB2013/001021 WO2013144722A2 (en) 2012-03-27 2013-03-27 Methods for detection of anti-cytomegalovirus neutralizing antibodies

Publications (2)

Publication Number Publication Date
BR112014023913A2 true BR112014023913A2 (pt) 2017-06-20
BR112014023913B1 BR112014023913B1 (pt) 2022-08-09

Family

ID=49261346

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014023913-4A BR112014023913B1 (pt) 2012-03-27 2013-03-27 Métodos para detecção de anticorpos neutralizantes de anticitomegalovírus

Country Status (11)

Country Link
US (2) US10006096B2 (pt)
EP (2) EP2831285B1 (pt)
JP (1) JP6265344B2 (pt)
KR (2) KR102146340B1 (pt)
CN (1) CN104321444A (pt)
AU (2) AU2013239383B2 (pt)
BR (1) BR112014023913B1 (pt)
CA (1) CA2867789C (pt)
MX (1) MX354822B (pt)
RU (1) RU2660712C2 (pt)
WO (1) WO2013144722A2 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013144722A2 (en) * 2012-03-27 2013-10-03 Variation Biotechnologies, Inc. Methods for detection of anti-cytomegalovirus neutralizing antibodies
US10611800B2 (en) 2016-03-11 2020-04-07 Pfizer Inc. Human cytomegalovirus gB polypeptide
JP6850483B2 (ja) * 2018-03-06 2021-03-31 株式会社CeSPIA Cell−based assay法に基づいたハイスループット抗体検出方法
WO2019232453A1 (en) * 2018-06-01 2019-12-05 Gravid Therapies, Inc. Methods, kits, and products for detection of cytomegalovirus infection
CN112805030A (zh) * 2018-08-14 2021-05-14 默沙东公司 利用成像细胞计数术的病毒中和测定法
US11629172B2 (en) 2018-12-21 2023-04-18 Pfizer Inc. Human cytomegalovirus gB polypeptide
CN111474339A (zh) * 2020-04-17 2020-07-31 浙江康佰裕生物科技有限公司 一种利用荧光标记痘病毒颗粒的方法及其应用
US11857622B2 (en) 2020-06-21 2024-01-02 Pfizer Inc. Human cytomegalovirus GB polypeptide
CN112362649A (zh) * 2020-11-09 2021-02-12 长春金赛药业有限责任公司 一种rhGH中和抗体的检测方法
CN112945919B (zh) * 2021-01-29 2023-04-28 上海睿钰生物科技有限公司 一种病毒中和抗体的检测方法、系统及其应用
WO2023141485A2 (en) * 2022-01-19 2023-07-27 Trustees Of Dartmouth College Systems and methods for deterring viral transmission using neural networks
WO2023154857A2 (en) * 2022-02-11 2023-08-17 Trustees Of Dartmouth College Systems and methods for identifying and treating primary and latent infections and/or determining time since infection

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6267965B1 (en) 1981-12-24 2001-07-31 Virogenetics Corporation Recombinant poxvirus—cytomegalovirus compositions and uses
US5248768A (en) * 1986-11-24 1993-09-28 The Children's Hospital, Incorporated Immunogenic glycoproteins of human cytomegalovirus
JPH06222062A (ja) * 1993-01-22 1994-08-12 Teijin Ltd ウイルス感染価および中和抗体価の測定法
DE19910044A1 (de) 1999-03-08 2000-09-14 Bodo Plachter Virale Partikel, die nach Infektion durch humanes Cytomegalovirus freigesetzt werden und ihre Verwendung als Impfstoff
US6569616B1 (en) * 1999-07-29 2003-05-27 Wisconsin Alumni Research Foundation Human cytomegalovirus glycoprotein O as a new drug target and subunit vaccine candidate
US6849409B2 (en) * 2000-10-16 2005-02-01 Axxima Pharmaceuticals Ag Cellular kinases involved in Cytomegalovirus infection and their inhibition
EP1587816B1 (en) 2002-12-23 2010-06-16 Vical Incorporated Codon-optimized polynucleotide-based vaccines against human cytomegalovirus infection
DE602004021260D1 (de) 2003-07-11 2009-07-09 Alphavax Inc Cytomegalovirusimpfstoffe, die auf dem alphavirus basieren
CN1686541A (zh) * 2005-04-11 2005-10-26 王明丽 人巨细胞病毒pp65蛋白质疫苗的制备方法
DK2066341T3 (en) 2006-09-01 2015-10-19 Csl Ltd PROCEDURE FOR INITIATING OR INDUCING AN IMMUNE RESPONSE
US9439960B2 (en) * 2007-10-10 2016-09-13 The Trustees Of Princeton University Cytomegalovirus vaccines and methods of production
PT2303923E (pt) * 2008-07-16 2015-08-25 Inst Research In Biomedicine Anticorpos neutralizantes de citomegalovírus humano e sua utilização
CA2700078A1 (en) * 2009-04-15 2010-10-15 Variation Biotechnologies Inc. Method and kit for detection of hepatitis a virus neutralizing antibodies
US9145577B2 (en) 2010-08-10 2015-09-29 The Research Foundation Of State University Of New York Lipoprotein lipase assay
CN104271745A (zh) * 2011-11-11 2015-01-07 变异生物技术公司 用于治疗巨细胞病毒的组合物和方法
WO2013144722A2 (en) * 2012-03-27 2013-10-03 Variation Biotechnologies, Inc. Methods for detection of anti-cytomegalovirus neutralizing antibodies

Also Published As

Publication number Publication date
EP3613431B1 (en) 2023-01-11
RU2660712C2 (ru) 2018-07-09
MX2014011504A (es) 2015-03-13
JP6265344B2 (ja) 2018-01-24
EP2831285A2 (en) 2015-02-04
KR102146340B1 (ko) 2020-08-24
US20150044668A1 (en) 2015-02-12
EP3613431A1 (en) 2020-02-26
RU2014142815A (ru) 2016-05-20
WO2013144722A2 (en) 2013-10-03
BR112014023913B1 (pt) 2022-08-09
EP2831285B1 (en) 2019-10-30
KR20200095575A (ko) 2020-08-10
AU2018271276A1 (en) 2018-12-20
US10161010B2 (en) 2018-12-25
CN104321444A (zh) 2015-01-28
JP2015518140A (ja) 2015-06-25
WO2013144722A3 (en) 2013-11-28
AU2013239383A1 (en) 2014-10-16
US20180274044A1 (en) 2018-09-27
AU2018271276B2 (en) 2021-06-03
MX354822B (es) 2018-03-21
KR102314245B1 (ko) 2021-10-20
KR20140146630A (ko) 2014-12-26
CA2867789A1 (en) 2013-10-03
CA2867789C (en) 2022-06-14
EP2831285A4 (en) 2015-10-28
AU2013239383B2 (en) 2018-10-04
US10006096B2 (en) 2018-06-26

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B25G Requested change of headquarter approved

Owner name: VARIATION BIOTECHNOLOGIES, INC. (CA)

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled

Owner name: VARIATION BIOTECHNOLOGIES, INC. (CA)

Free format text: ANULADA A PUBLICACAO CODIGO 25.7 NA RPI NO 2648 DE 05/10/2021 POR TER SIDO INDEVIDA.

B25G Requested change of headquarter approved

Owner name: VARIATION BIOTECHNOLOGIES, INC. (CA)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B25D Requested change of name of applicant approved

Owner name: VARIATION BIOTECHNOLOGIES INC. (CA)

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/03/2013, OBSERVADAS AS CONDICOES LEGAIS