BR112014023296A2 - métodos para fazer tipagem de uma amostra de um paciente com hepatite b, para determinar se um paciente com hepatite b tem uma chance melhorada de um resultado positivo do tratamento da hepatite b, se um indivíduo tem uma predisposição genética para uma chance melhorada para um resultado positivo de tratamento da hepatite b, para identificar um gene, e para ensaiar quanto a presença de ácido nucleico, kit de partes ou arranjo ou microarranjo ou vetor, usos de pelo menos um polinucleotídeo isolado, de um kit de partes ou arranjo ou microarranjo ou vetor e de meios para determinar um nível de expressão de carnitina e/ou um derivado de carnitina - Google Patents
métodos para fazer tipagem de uma amostra de um paciente com hepatite b, para determinar se um paciente com hepatite b tem uma chance melhorada de um resultado positivo do tratamento da hepatite b, se um indivíduo tem uma predisposição genética para uma chance melhorada para um resultado positivo de tratamento da hepatite b, para identificar um gene, e para ensaiar quanto a presença de ácido nucleico, kit de partes ou arranjo ou microarranjo ou vetor, usos de pelo menos um polinucleotídeo isolado, de um kit de partes ou arranjo ou microarranjo ou vetor e de meios para determinar um nível de expressão de carnitina e/ou um derivado de carnitinaInfo
- Publication number
- BR112014023296A2 BR112014023296A2 BR112014023296A BR112014023296A BR112014023296A2 BR 112014023296 A2 BR112014023296 A2 BR 112014023296A2 BR 112014023296 A BR112014023296 A BR 112014023296A BR 112014023296 A BR112014023296 A BR 112014023296A BR 112014023296 A2 BR112014023296 A2 BR 112014023296A2
- Authority
- BR
- Brazil
- Prior art keywords
- hepatitis
- microarray
- kit
- vector
- patient
- Prior art date
Links
- 208000006454 hepatitis Diseases 0.000 title 4
- 231100000283 hepatitis Toxicity 0.000 title 4
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 2
- 238000002493 microarray Methods 0.000 title 2
- 208000034826 Genetic Predisposition to Disease Diseases 0.000 title 1
- 229960004203 carnitine Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5761—Hepatitis B
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/131—Allele specific probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12160199 | 2012-03-19 | ||
| EP12186188 | 2012-09-26 | ||
| PCT/NL2013/050204 WO2013141705A2 (en) | 2012-03-19 | 2013-03-19 | Means and methods for response prediction of hepatitis b treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014023296A2 true BR112014023296A2 (pt) | 2019-09-24 |
Family
ID=47997743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014023296A BR112014023296A2 (pt) | 2012-03-19 | 2013-03-19 | métodos para fazer tipagem de uma amostra de um paciente com hepatite b, para determinar se um paciente com hepatite b tem uma chance melhorada de um resultado positivo do tratamento da hepatite b, se um indivíduo tem uma predisposição genética para uma chance melhorada para um resultado positivo de tratamento da hepatite b, para identificar um gene, e para ensaiar quanto a presença de ácido nucleico, kit de partes ou arranjo ou microarranjo ou vetor, usos de pelo menos um polinucleotídeo isolado, de um kit de partes ou arranjo ou microarranjo ou vetor e de meios para determinar um nível de expressão de carnitina e/ou um derivado de carnitina |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20150044167A1 (enExample) |
| EP (1) | EP2828401B1 (enExample) |
| BR (1) | BR112014023296A2 (enExample) |
| ES (1) | ES2657266T3 (enExample) |
| HK (1) | HK1206791A1 (enExample) |
| IN (1) | IN2014MN01989A (enExample) |
| MX (1) | MX2014011256A (enExample) |
| RU (1) | RU2640256C2 (enExample) |
| WO (1) | WO2013141705A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105829548A (zh) * | 2013-12-17 | 2016-08-03 | 豪夫迈·罗氏有限公司 | 用于hbv治疗反应的生物标记物 |
| EP3322820A1 (en) * | 2015-07-15 | 2018-05-23 | H. Hoffnabb-La Roche Ag | Biomarkers for hbv treatment response |
| CN109504763B (zh) * | 2018-12-17 | 2020-09-04 | 北京三元基因药业股份有限公司 | 用于预测α干扰素治疗乙肝患者疗效的分子标记 |
| UA129589C2 (uk) | 2018-12-19 | 2025-06-11 | Лео Фарма А/С | Аніліди амінокислот як низькомолекулярні модулятори il-17 |
| CN115267193B (zh) * | 2022-09-20 | 2022-12-27 | 北京大学 | 用于判断生物样本中HBsAg来源的方法及系统和用途 |
-
2013
- 2013-03-19 EP EP13712387.3A patent/EP2828401B1/en not_active Not-in-force
- 2013-03-19 HK HK15107184.4A patent/HK1206791A1/xx unknown
- 2013-03-19 US US14/386,176 patent/US20150044167A1/en not_active Abandoned
- 2013-03-19 MX MX2014011256A patent/MX2014011256A/es unknown
- 2013-03-19 BR BR112014023296A patent/BR112014023296A2/pt not_active IP Right Cessation
- 2013-03-19 WO PCT/NL2013/050204 patent/WO2013141705A2/en not_active Ceased
- 2013-03-19 IN IN1989MUN2014 patent/IN2014MN01989A/en unknown
- 2013-03-19 RU RU2014142009A patent/RU2640256C2/ru not_active IP Right Cessation
- 2013-03-19 ES ES13712387.3T patent/ES2657266T3/es active Active
-
2017
- 2017-08-29 US US15/689,582 patent/US20180044735A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HK1206791A1 (en) | 2016-01-15 |
| MX2014011256A (es) | 2015-07-14 |
| US20150044167A1 (en) | 2015-02-12 |
| IN2014MN01989A (enExample) | 2015-07-10 |
| WO2013141705A3 (en) | 2013-12-05 |
| US20180044735A1 (en) | 2018-02-15 |
| RU2014142009A (ru) | 2016-05-10 |
| ES2657266T3 (es) | 2018-03-02 |
| EP2828401A2 (en) | 2015-01-28 |
| EP2828401B1 (en) | 2017-10-25 |
| WO2013141705A2 (en) | 2013-09-26 |
| RU2640256C2 (ru) | 2017-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |