BR112014020450A8 - hidrogéis à base de cucurbiturila - Google Patents

hidrogéis à base de cucurbiturila

Info

Publication number
BR112014020450A8
BR112014020450A8 BR112014020450A BR112014020450A BR112014020450A8 BR 112014020450 A8 BR112014020450 A8 BR 112014020450A8 BR 112014020450 A BR112014020450 A BR 112014020450A BR 112014020450 A BR112014020450 A BR 112014020450A BR 112014020450 A8 BR112014020450 A8 BR 112014020450A8
Authority
BR
Brazil
Prior art keywords
cucurbituril
based hydrogels
hydrogels
Prior art date
Application number
BR112014020450A
Other languages
English (en)
Other versions
BR112014020450A2 (pt
BR112014020450B1 (pt
Inventor
appel Eric
Biedermann Frank
Rowland Matthew
Scherman Oren
Jun Loh Xian
Original Assignee
Cambridge Entpr Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1202834.6A external-priority patent/GB201202834D0/en
Priority claimed from GBGB1301648.0A external-priority patent/GB201301648D0/en
Application filed by Cambridge Entpr Ltd filed Critical Cambridge Entpr Ltd
Publication of BR112014020450A2 publication Critical patent/BR112014020450A2/pt
Publication of BR112014020450A8 publication Critical patent/BR112014020450A8/pt
Publication of BR112014020450B1 publication Critical patent/BR112014020450B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A61K38/385—Serum albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/02—Alkyl or cycloalkyl ethers
    • C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
    • C08B11/08—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals with hydroxylated hydrocarbon radicals; Esters, ethers, or acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/02—Alkyl or cycloalkyl ethers
    • C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
    • C08B11/10—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals
    • C08B11/12—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals substituted with carboxylic radicals, e.g. carboxymethylcellulose [CMC]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
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    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
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    • C—CHEMISTRY; METALLURGY
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    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
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    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
    • C08G18/6484—Polysaccharides and derivatives thereof
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    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
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    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/246—Intercrosslinking of at least two polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/02—Cellulose; Modified cellulose
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/286—Alkyl ethers substituted with acid radicals, e.g. carboxymethyl cellulose [CMC]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L39/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16—Cyclodextrin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2210/00—Compositions for preparing hydrogels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2300/00—Characterised by the use of unspecified polymers
    • C08J2300/10—Polymers characterised by the presence of specified groups, e.g. terminal or pendant functional groups
    • C—CHEMISTRY; METALLURGY
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    • C08J2300/00—Characterised by the use of unspecified polymers
    • C08J2300/20—Polymers characterized by their physical structure
    • C08J2300/204—Supramolecular materials
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    • C08J2300/00—Characterised by the use of unspecified polymers
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    • C08J2300/208—Interpenetrating networks [IPN]
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    • C08J2300/00—Characterised by the use of unspecified polymers
    • C08J2300/20—Polymers characterized by their physical structure
    • C08J2300/21—Polyrotaxanes; Polycatenanes
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
    • C08J2301/08—Cellulose derivatives
    • C08J2301/26—Cellulose ethers
    • C08J2301/28—Alkyl ethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/16—Cyclodextrin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2329/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Derivatives of such polymer
    • C08J2329/02—Homopolymers or copolymers of unsaturated alcohols
    • C08J2329/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2375/00—Characterised by the use of polyureas or polyurethanes; Derivatives of such polymers
    • C08J2375/02—Polyureas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01017—Lysozyme (3.2.1.17)
BR112014020450-0A 2012-02-20 2013-02-20 hidrogéis à base de cucurbiturila e métodos para preparação dos ditos hidrogéis BR112014020450B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1202834.6A GB201202834D0 (en) 2012-02-20 2012-02-20 Cucurbituril-based hydrogels
GB1202834.6 2012-02-20
GBGB1301648.0A GB201301648D0 (en) 2013-01-30 2013-01-30 Nested supramolecular capsules
GB1301648.0 2013-01-30
PCT/GB2013/050414 WO2013124654A1 (en) 2012-02-20 2013-02-20 Cucurbituril-based hydrogels

Publications (3)

Publication Number Publication Date
BR112014020450A2 BR112014020450A2 (pt) 2017-06-20
BR112014020450A8 true BR112014020450A8 (pt) 2018-01-16
BR112014020450B1 BR112014020450B1 (pt) 2020-12-08

Family

ID=47754860

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014020450-0A BR112014020450B1 (pt) 2012-02-20 2013-02-20 hidrogéis à base de cucurbiturila e métodos para preparação dos ditos hidrogéis

Country Status (7)

Country Link
US (1) US11491227B2 (pt)
EP (1) EP2817359B9 (pt)
CN (1) CN104245801B (pt)
BR (1) BR112014020450B1 (pt)
ES (1) ES2759112T3 (pt)
WO (1) WO2013124654A1 (pt)
ZA (1) ZA201406007B (pt)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201301648D0 (en) 2013-01-30 2013-03-13 Cambridge Entpr Ltd Nested supramolecular capsules
US10258698B2 (en) 2013-03-14 2019-04-16 Modernatx, Inc. Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
WO2015034925A1 (en) 2013-09-03 2015-03-12 Moderna Therapeutics, Inc. Circular polynucleotides
US20160194625A1 (en) 2013-09-03 2016-07-07 Moderna Therapeutics, Inc. Chimeric polynucleotides
WO2015153217A1 (en) * 2014-04-02 2015-10-08 Dow Global Technologies Llc Cellulose ethers having 1,2,3-triazolyl substituents
CN103962112B (zh) * 2014-05-13 2016-06-29 东南大学 用于细胞三维培养的光响应智能凝胶微球的制备方法
US10323104B2 (en) 2014-08-02 2019-06-18 Lg Chem, Ltd. Dye complex, photoconversion film and electronic element including same
WO2016049360A1 (en) 2014-09-24 2016-03-31 Massachusetts Institute Of Technology Shear-thinning self-healing networks
CN105061775B (zh) * 2015-08-09 2017-08-01 大连理工大学 一种通过葫芦脲阴离子组装制备新型有机固体荧光材料的方法
CN105112050B (zh) * 2015-10-15 2017-03-08 南开大学 一种溶剂可调的荧光材料及其准聚轮烷水凝胶的制备方法
US10532130B2 (en) 2015-12-04 2020-01-14 Colorado State University Research Foundation Soft tissue mimetics and thermoplastic elastomer hydrogels
CN105837744A (zh) * 2016-06-12 2016-08-10 江苏华昌织物有限公司 一种基于冠醚的双重敏感高分子水凝胶的制备方法
US10125228B2 (en) * 2016-08-22 2018-11-13 Colorado State University Research Foundation Phototunable thermoplastic elastomer hydrogel networks
US10590257B2 (en) 2016-09-26 2020-03-17 The Board Of Trustees Of The Leland Stanford Junior University Biomimetic, moldable, self-assembled cellulose silica-based trimeric hydrogels and their use as viscosity modifying carriers in industrial applications
GB201617469D0 (en) 2016-10-14 2016-11-30 Cambridge Entpr Ltd Cucurbituril-based hydrogels
CN110325218B (zh) * 2016-10-14 2023-05-16 奥伦·谢尔曼 基于葫芦脲的水凝胶
US11969526B2 (en) 2017-04-03 2024-04-30 The Board Of Trustees Of The Leland Stanford Junior University Adhesion prevention with shear-thinning polymeric hydrogels
CN110891952B (zh) * 2017-04-28 2022-10-11 伯努瓦·普里厄 作为氧载体的葫芦脲衍生物
CN107033281B (zh) * 2017-05-05 2019-01-15 南开大学 一种溶胀性能优异的荧光水凝胶及其制备方法
CN109206575A (zh) * 2017-06-30 2019-01-15 翁秋梅 一种杂化交联动态聚合物
CN109422836A (zh) * 2017-06-30 2019-03-05 翁秋梅 一种含有组合超分子作用的动态交联聚合物
CN109206576A (zh) * 2017-06-30 2019-01-15 翁秋梅 一种杂化交联动态聚合物
CN109208110B (zh) * 2017-07-01 2020-06-09 中国石油化工股份有限公司 一种基于非球形多孔微粒的类蜘蛛丝聚合物纤维及其制备方法
CN107936262B (zh) * 2017-12-07 2020-07-28 西北师范大学 一种超分子聚合物框架材料的制备及应用
GB201804634D0 (en) 2018-03-22 2018-05-09 Aqdot Ltd Emulsion stabiliser
US11975123B2 (en) 2018-04-02 2024-05-07 The Board Of Trustees Of The Leland Stanford Junior University Adhesion prevention with shear-thinning polymeric hydrogels
CN108610615B (zh) * 2018-05-08 2019-07-09 西南交通大学 一种超分子水凝胶及其制备方法
CN109081927B (zh) * 2018-06-25 2020-07-03 天津科技大学 一种水凝胶的制备方法
CN109160995B (zh) * 2018-08-19 2021-02-23 南京理工大学 一种柱[5]芳烃自组装弹性体材料及其制备方法
US20210338801A1 (en) * 2018-10-01 2021-11-04 The Board Of Trustees Of The Leland Stanford Junior University Injectable hydrogels for controlled release of immunomodulatory compounds
CN109705372B (zh) * 2018-12-29 2021-08-13 广东工业大学 一种超分子材料和水凝胶及其制备方法
CN110484242B (zh) * 2019-08-28 2022-05-17 贵州大学 一种检测水中三价铁离子的荧光探针及其制备和检测方法
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CN113501974B (zh) * 2021-07-28 2023-11-24 洛阳师范学院 一种室温磷光水凝胶的制备方法、产品及应用
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CN113943197B (zh) * 2021-11-10 2022-06-28 南京理工大学 一种二茂铁基大环复合燃速催化剂及其制备方法和用途
CN115521507B (zh) * 2022-10-26 2023-09-26 清华大学 透明质酸超分子水凝胶及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19825486C2 (de) 1998-06-08 2000-07-06 Stockhausen Chem Fab Gmbh Wasserabsorbierende Polymere mit supramolekularen Hohlraummolekülen, Verfahren zu deren Herstellung und deren Verwendung
DE60007257T2 (de) 1999-10-21 2004-09-16 Pohang University Of Science And Technology Foundation, Pohang Verfahren zur Herstellung von Cucurbituril Derivaten
US7060498B1 (en) 2001-11-28 2006-06-13 Genta Salus Llc Polycationic water soluble copolymer and method for transferring polyanionic macromolecules across biological barriers
FR2842106B1 (fr) 2002-07-11 2006-07-14 Centre Nat Rech Scient Dispersions aqueuses de particules nanometriques ou micrometriques pour l'encapsulation de composes chimiques
US7727969B2 (en) 2003-06-06 2010-06-01 Massachusetts Institute Of Technology Controlled release nanoparticle having bound oligonucleotide for targeted delivery
KR100499278B1 (ko) 2003-07-05 2005-07-01 학교법인 포항공과대학교 로텍산 화합물이 공유결합된 고체 기판 및 이를 이용한바이오칩
CA2537736A1 (en) 2003-09-04 2005-03-17 Technion Research And Development Foundation Ltd. Synthetic binding pairs comprising cucurbituril derivatives and polyammonium compounds and uses thereof
KR20050102295A (ko) 2004-04-21 2005-10-26 학교법인 포항공과대학교 리포좀 및 그 제조방법
US20050250551A1 (en) 2004-05-10 2005-11-10 Nokia Corporation Notification about an event
EP1951723B1 (en) 2005-10-20 2017-08-30 Postech Academy-Industry Foundation The application using non-covalent bond between a cucurbituril derivative and a ligand
JP2007211060A (ja) 2006-02-07 2007-08-23 Japan Advanced Institute Of Science & Technology Hokuriku 超分子ポリマー及びその合成方法
WO2007106144A1 (en) 2006-02-28 2007-09-20 University Of Maryland NOR-SECO-, BIS-NOR-SECO, TRIS-NOR-SECO- AND HIGHER NOR-SECO- CUCURBIT[n]URIL COMPOUNDS
WO2008096360A2 (en) 2007-02-06 2008-08-14 Technion Research & Development Foundation Ltd. Frictionless molecular rotary motors
GB0723714D0 (en) 2007-12-04 2008-01-16 Cambridge Entpr Ltd Supramolecular handcuffs in polymeric architecture
US10464811B2 (en) 2009-04-06 2019-11-05 Nanyang Technological University Method of forming a particulate porous metal oxide or metalloid oxide
GB0922623D0 (en) 2009-12-23 2010-02-10 Cambridge Entpr Ltd Methods for the purification of cucurbituril
WO2013014452A1 (en) 2011-07-26 2013-01-31 Cambridge Enterprise Limited Supramolecular capsules
US9827321B2 (en) * 2012-08-14 2017-11-28 The Trustees Of The University Of Pennsylvania Stabilizing shear-thinning hydrogels

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