BR112014019578A2 - Proteína, molécula de dna, células eucarióticase de levedura geneticamente modificada, usos de proteína, de molécula de dna e de células eucarióticas e processos de produção de etanol e de geração de produto de fermentação - Google Patents

Proteína, molécula de dna, células eucarióticase de levedura geneticamente modificada, usos de proteína, de molécula de dna e de células eucarióticas e processos de produção de etanol e de geração de produto de fermentação

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Publication number
BR112014019578A2
BR112014019578A2 BR112014019578-1A BR112014019578A BR112014019578A2 BR 112014019578 A2 BR112014019578 A2 BR 112014019578A2 BR 112014019578 A BR112014019578 A BR 112014019578A BR 112014019578 A2 BR112014019578 A2 BR 112014019578A2
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BR
Brazil
Prior art keywords
protein
cells
euchariotic
dna
dna molecule
Prior art date
Application number
BR112014019578-1A
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English (en)
Other versions
BR112014019578A8 (pt
BR112014019578B1 (pt
Inventor
Dragovic Zdravko
Gamauf Christian
Reisinger Christoph
Kettling Ulrich
Original Assignee
Clariant Produkte (Deutschland) Gmbh
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Publication date
Application filed by Clariant Produkte (Deutschland) Gmbh filed Critical Clariant Produkte (Deutschland) Gmbh
Publication of BR112014019578A8 publication Critical patent/BR112014019578A8/pt
Publication of BR112014019578A2 publication Critical patent/BR112014019578A2/pt
Publication of BR112014019578B1 publication Critical patent/BR112014019578B1/pt

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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
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    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
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    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
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    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
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    • C12P7/16—Butanols
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C12P7/20—Glycerol
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
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    • C12P7/00—Preparation of oxygen-containing organic compounds
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    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01005—Xylose isomerase (5.3.1.5)
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    • C12P2203/00—Fermentation products obtained from optionally pretreated or hydrolyzed cellulosic or lignocellulosic material as the carbon source
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Plant Pathology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

proteína, molécula de dna, células eucarióticas e de levedura geneticamente modificada, usos de proteína, de molécula de dna e de células eucarióticas e processos de produção de etanol e de geração de produto de fermentação a presente invenção fornece uma célula eucariótica microbiana capaz de utilizar açúcares c5, particularmente xilose. outro objetivo da presente invenção é o fornecimento de uma sequência de proteínas aprimorada para permitir que as células eucarióticas degradem açúcares c5. a presente invenção fornece, portanto, proteínas que compreendem uma sequência de aminoácidos que possui identidade de pelo menos 75%, preferencialmente identidade de 80%, de maior preferência identidade de 90% e, de preferência superior, identidade de 95% com seq id n° 2 ou seq id n° 8 e possui atividade de isomerase de xilose em células eucarióticas.
BR112014019578-1A 2012-02-07 2013-02-07 Células de saccharomyces cerevisiae, usos das ditas células e molécula de dna e processos para a produção de etanol e de produto de fermentação BR112014019578B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12000783.6A EP2626423A1 (en) 2012-02-07 2012-02-07 Pentose-fermenting microorganism
EP12000783.6 2012-02-07
PCT/EP2013/052407 WO2013117631A1 (en) 2012-02-07 2013-02-07 Pentose fermenting microorganisms

Publications (3)

Publication Number Publication Date
BR112014019578A8 BR112014019578A8 (pt) 2017-07-11
BR112014019578A2 true BR112014019578A2 (pt) 2019-10-15
BR112014019578B1 BR112014019578B1 (pt) 2022-10-11

Family

ID=47750621

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014019578-1A BR112014019578B1 (pt) 2012-02-07 2013-02-07 Células de saccharomyces cerevisiae, usos das ditas células e molécula de dna e processos para a produção de etanol e de produto de fermentação

Country Status (19)

Country Link
US (2) US20140377813A1 (pt)
EP (2) EP2626423A1 (pt)
CN (1) CN104204202B (pt)
AU (1) AU2013218001B2 (pt)
BR (1) BR112014019578B1 (pt)
CA (1) CA2863734C (pt)
DK (1) DK2812430T3 (pt)
EA (1) EA035000B1 (pt)
ES (1) ES2643046T3 (pt)
HR (1) HRP20171583T1 (pt)
HU (1) HUE035703T2 (pt)
MX (1) MX350005B (pt)
MY (1) MY171359A (pt)
NO (1) NO2812430T3 (pt)
PL (1) PL2812430T3 (pt)
RS (1) RS56569B1 (pt)
SI (1) SI2812430T1 (pt)
WO (1) WO2013117631A1 (pt)
ZA (1) ZA201405761B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
BR112018000690A2 (pt) 2015-07-13 2018-09-18 MARA Renewables Corporation micro-organismo recombinante, e, métodos para preparar um micro-organismo de metabolização de xilose e para produzir óleo.
BR112018002284A2 (pt) 2015-08-05 2018-12-11 Cargill Inc método de fermentação para produzir um bioproduto, levedura crabtree negativa geneticamente engenheirada e método para reduzir a produção de glicerol por uma levedura engenheirada
EP3559210A1 (en) * 2016-12-21 2019-10-30 Vib Vzw Xylose isomerases that confer efficient xylose fermentation capability to yeast

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60325457D1 (de) * 2002-01-23 2009-02-05 Royal Nedalco B V Fermentation von pentosezuckern
DE102008031350B4 (de) * 2008-07-02 2011-02-10 Johann Wolfgang Goethe-Universität Frankfurt am Main Prokaryotische Xylose-Isomerase zur Konstruktion Xylose-vergärender Hefen
CA2785276C (en) * 2009-12-22 2019-04-23 Kabushiki Kaisha Toyota Chuo Kenkyusho Xylose isomerase and use thereof
WO2012009272A2 (en) * 2010-07-14 2012-01-19 Codexis, Inc. Pentose fermentation by a recombinant microorganism

Also Published As

Publication number Publication date
US20140377813A1 (en) 2014-12-25
NO2812430T3 (pt) 2018-02-03
MY171359A (en) 2019-10-10
BR112014019578A8 (pt) 2017-07-11
AU2013218001B2 (en) 2016-02-18
EP2812430B1 (en) 2017-09-06
HRP20171583T1 (hr) 2017-12-01
CA2863734A1 (en) 2013-08-15
SI2812430T1 (en) 2018-03-30
EA201400877A1 (ru) 2015-01-30
ES2643046T3 (es) 2017-11-21
US20160312177A1 (en) 2016-10-27
CN104204202A (zh) 2014-12-10
EA035000B1 (ru) 2020-04-16
RS56569B1 (sr) 2018-02-28
CN104204202B (zh) 2017-08-01
WO2013117631A1 (en) 2013-08-15
CA2863734C (en) 2020-03-24
MX350005B (es) 2017-08-22
AU2013218001A1 (en) 2014-08-28
EP2626423A1 (en) 2013-08-14
EP2812430A1 (en) 2014-12-17
BR112014019578B1 (pt) 2022-10-11
DK2812430T3 (en) 2017-10-23
HUE035703T2 (en) 2018-05-28
ZA201405761B (en) 2015-11-25
PL2812430T3 (pl) 2018-02-28
MX2014009496A (es) 2014-09-11

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