BR112014017836A8 - Composição de enchimento ósseo - Google Patents

Composição de enchimento ósseo

Info

Publication number
BR112014017836A8
BR112014017836A8 BR112014017836A BR112014017836A BR112014017836A8 BR 112014017836 A8 BR112014017836 A8 BR 112014017836A8 BR 112014017836 A BR112014017836 A BR 112014017836A BR 112014017836 A BR112014017836 A BR 112014017836A BR 112014017836 A8 BR112014017836 A8 BR 112014017836A8
Authority
BR
Brazil
Prior art keywords
bone filler
filler composition
formulation
bisphosphonate
calcium phosphate
Prior art date
Application number
BR112014017836A
Other languages
English (en)
Other versions
BR112014017836B1 (pt
BR112014017836A2 (pt
Inventor
Abdul Majeed Ali Saad
Original Assignee
Depuy Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Int Ltd filed Critical Depuy Int Ltd
Publication of BR112014017836A2 publication Critical patent/BR112014017836A2/pt
Publication of BR112014017836A8 publication Critical patent/BR112014017836A8/pt
Publication of BR112014017836B1 publication Critical patent/BR112014017836B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials Engineering (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

COMPOSIÇÃO DE ENCHIMENTO ÓSSEO. A presente invenção refere-se a uma composição de enchimento ósseo que compreende uma mistura de um enchimento ósseo curável à base de fosfato de cálcio, que é formado, a partir de um componente líquido e um componente em pó à base de fosfato de cálcio, e uma formulação que compreende um bisfosfonato sob a forma de particulado. As partículas do bisfosfonato são embutidas em partículas de um material polimérico que é reabsorvido quando a formulação é implantada.
BR112014017836A 2012-01-19 2013-01-18 composição de enchimento ósseo BR112014017836B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201200868A GB201200868D0 (en) 2012-01-19 2012-01-19 Bone filler composition
PCT/GB2013/050107 WO2013108035A1 (en) 2012-01-19 2013-01-18 Bone filler composition

Publications (3)

Publication Number Publication Date
BR112014017836A2 BR112014017836A2 (pt) 2017-06-20
BR112014017836A8 true BR112014017836A8 (pt) 2017-07-11
BR112014017836B1 BR112014017836B1 (pt) 2019-10-22

Family

ID=45814216

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014017836A BR112014017836B1 (pt) 2012-01-19 2013-01-18 composição de enchimento ósseo

Country Status (12)

Country Link
US (2) US20140370100A1 (pt)
EP (2) EP3150235B1 (pt)
JP (1) JP6184980B2 (pt)
KR (1) KR102145734B1 (pt)
CN (1) CN104105509B (pt)
AU (1) AU2013210877B2 (pt)
BR (1) BR112014017836B1 (pt)
CA (1) CA2861590C (pt)
ES (2) ES2687117T3 (pt)
GB (1) GB201200868D0 (pt)
RU (1) RU2621151C2 (pt)
WO (1) WO2013108035A1 (pt)

Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
CN105056298B (zh) * 2015-08-25 2018-01-02 华南理工大学 一种具有表面大孔的多孔磷酸钙微球材料、制备方法及应用
WO2017062737A1 (en) 2015-10-08 2017-04-13 Zimmer Knee Creations, Inc. Curable calcium phosphate compositions for use with porous structures and methods of using the same
JP2018019944A (ja) * 2016-08-04 2018-02-08 国立大学法人 名古屋工業大学 生分解性繊維からなる骨再生用材料、及び骨再生用材料を製造するための方法
BR112019004499B1 (pt) * 2016-09-08 2022-07-12 Karl Leibinger Medizintechnik Gmbh & Co. Kg Implante compreendendo um pó compósito contendo sal de cálcio tendo partículas microestruturadas
RU2702520C1 (ru) * 2019-04-17 2019-10-08 Анна Владимировна Алабут Способ эндопротезирования коленного сустава у пациентов с остеопорозом
CN113116858A (zh) * 2021-03-26 2021-07-16 张皓轩 一种载伊班膦酸钠plga微球及采用该微球的复合组织工程骨的制备方法

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FR2531088B1 (fr) 1982-07-29 1987-08-28 Sanofi Sa Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
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Also Published As

Publication number Publication date
EP2804636B1 (en) 2016-11-30
KR102145734B1 (ko) 2020-08-19
CN104105509B (zh) 2016-08-24
CA2861590A1 (en) 2013-07-25
BR112014017836B1 (pt) 2019-10-22
ES2616484T3 (es) 2017-06-13
US20180110899A1 (en) 2018-04-26
BR112014017836A2 (pt) 2017-06-20
CN104105509A (zh) 2014-10-15
EP3150235B1 (en) 2018-08-01
US20140370100A1 (en) 2014-12-18
AU2013210877A1 (en) 2014-07-10
ES2687117T3 (es) 2018-10-23
AU2013210877B2 (en) 2016-01-07
CA2861590C (en) 2020-04-21
JP2015509018A (ja) 2015-03-26
KR20140121846A (ko) 2014-10-16
JP6184980B2 (ja) 2017-08-23
RU2621151C2 (ru) 2017-05-31
WO2013108035A1 (en) 2013-07-25
GB201200868D0 (en) 2012-02-29
RU2014133859A (ru) 2016-03-20
EP3150235A1 (en) 2017-04-05
EP2804636A1 (en) 2014-11-26

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/01/2013, OBSERVADAS AS CONDICOES LEGAIS.