BR112014017140A8 - método de determinação da presença de moléculas alvo em um fluido corporal compreendendo células; cartucho para inserção em um dispositivo analisador; e dispositivo analisador - Google Patents

método de determinação da presença de moléculas alvo em um fluido corporal compreendendo células; cartucho para inserção em um dispositivo analisador; e dispositivo analisador

Info

Publication number
BR112014017140A8
BR112014017140A8 BR112014017140A BR112014017140A BR112014017140A8 BR 112014017140 A8 BR112014017140 A8 BR 112014017140A8 BR 112014017140 A BR112014017140 A BR 112014017140A BR 112014017140 A BR112014017140 A BR 112014017140A BR 112014017140 A8 BR112014017140 A8 BR 112014017140A8
Authority
BR
Brazil
Prior art keywords
analyzer device
body fluid
cells
determining
target molecules
Prior art date
Application number
BR112014017140A
Other languages
English (en)
Other versions
BR112014017140A2 (pt
Inventor
De Regt Bram
Garrelina Orsel Joukje
De Kievit Peggy
Uyen Dittmer Wendy
Original Assignee
Koninklijke Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Nv filed Critical Koninklijke Philips Nv
Publication of BR112014017140A2 publication Critical patent/BR112014017140A2/pt
Publication of BR112014017140A8 publication Critical patent/BR112014017140A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0429—Sample carriers adapted for special purposes

Abstract

resumo método de determinação da presença de moléculas alvo em um fluido corporal compreendendo células; cartucho para inserção em um dispositivo analisador; e dispositivo analisador um método de determinação de uma presença de moléculas alvo em um fluido corporal 16 com células compreendendo as etapas de: lise das células no fluido corporal 16 para gerar um lisado 17; mistura do lisado 16 com partículas 36 com as moléculas do primeiro detector; ligação da molécula alvo nas partículas através das moléculas do primeiro detector; exposição de um substrato 38 com as moléculas do segundo detector para o lisado 17; ligação das moléculas alvo no substrato através das moléculas do segundo detector; detecção das partículas 36 anexadas ao substrato 36. 1/1
BR112014017140A 2012-01-16 2013-01-14 método de determinação da presença de moléculas alvo em um fluido corporal compreendendo células; cartucho para inserção em um dispositivo analisador; e dispositivo analisador BR112014017140A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261586879P 2012-01-16 2012-01-16
PCT/IB2013/050335 WO2013108168A2 (en) 2012-01-16 2013-01-14 Determining a presence of target molecules in a body fluid comprising cells

Publications (2)

Publication Number Publication Date
BR112014017140A2 BR112014017140A2 (pt) 2017-06-13
BR112014017140A8 true BR112014017140A8 (pt) 2017-07-04

Family

ID=47833316

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014017140A BR112014017140A8 (pt) 2012-01-16 2013-01-14 método de determinação da presença de moléculas alvo em um fluido corporal compreendendo células; cartucho para inserção em um dispositivo analisador; e dispositivo analisador

Country Status (7)

Country Link
US (1) US20150004624A1 (pt)
EP (1) EP2805164B1 (pt)
JP (1) JP6335792B2 (pt)
CN (1) CN104053992B (pt)
BR (1) BR112014017140A8 (pt)
RU (1) RU2014133714A (pt)
WO (1) WO2013108168A2 (pt)

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JP6635897B2 (ja) * 2016-08-30 2020-01-29 シスメックス株式会社 試料分析用カートリッジ及びその製造方法、並びにその利用
EP3526587B1 (en) * 2016-10-13 2024-05-01 Instrumentation Laboratory Company Total protein measurement using whole blood refractometry
CA3187872A1 (en) 2020-08-03 2022-02-10 Jeffrey R. Jasperse Lysis devices having a piezo element and methods

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Also Published As

Publication number Publication date
BR112014017140A2 (pt) 2017-06-13
EP2805164B1 (en) 2017-11-08
JP2015503760A (ja) 2015-02-02
JP6335792B2 (ja) 2018-05-30
CN104053992A (zh) 2014-09-17
US20150004624A1 (en) 2015-01-01
EP2805164A2 (en) 2014-11-26
WO2013108168A3 (en) 2013-10-31
RU2014133714A (ru) 2016-03-10
CN104053992B (zh) 2016-12-14
WO2013108168A2 (en) 2013-07-25

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]