BR112014016632A8 - uso terapêutico de derivados de imidazopiridina - Google Patents
uso terapêutico de derivados de imidazopiridinaInfo
- Publication number
- BR112014016632A8 BR112014016632A8 BR112014016632A BR112014016632A BR112014016632A8 BR 112014016632 A8 BR112014016632 A8 BR 112014016632A8 BR 112014016632 A BR112014016632 A BR 112014016632A BR 112014016632 A BR112014016632 A BR 112014016632A BR 112014016632 A8 BR112014016632 A8 BR 112014016632A8
- Authority
- BR
- Brazil
- Prior art keywords
- attached
- phenyl nucleus
- therapeutic use
- imidazopyridine derivatives
- carbon atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
abstract therapeutic use of imidazopyridine derivatives the invention relates to the use of compounds corresponding to formula (i): in which - r2 and r3 together form, with the carbon atoms of the phenyl nucleus to which they are attached, a 6-membered nitrogenous heterocycle corresponding to one of the formulae (a), (b) and (c) below: in which the wavy lines represent the phenyl nucleus to which r2 and r3 are attached, or of a pharmaceutically acceptable salt thereof, for preparing a medicament for the treatment of bladder cancer. _______________________________________________________________ tradução do resumo resumo patente de invenção: "uso terapêutico de derivados de imidazopiridina". a presente invenção refere-se ao uso de compostos correspondendo à fórmula (i) onde r2 e r3 juntos formam, com os átomos de carbono do núcleo fenila ao qual eles estão ligados, um heterociclo nitrogenoso de 6 membros correspondendo a uma das fórmulas (a), (b) e (c) onde as linhas pontilhadas representam o núcleo fenila ao qual r2 e r3 estão ligados, ou um sal farmaceuticamente aceitável do mesmo, para preparação de um medicamento para o tratamento de câncer de bexiga.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1250075A FR2985185B1 (fr) | 2012-01-04 | 2012-01-04 | Utilisation en therapeutique de derives d'imidazopyridine |
| PCT/IB2013/050048 WO2013102860A1 (en) | 2012-01-04 | 2013-01-03 | Therapeutic use of imidazopyridine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014016632A2 BR112014016632A2 (pt) | 2017-06-13 |
| BR112014016632A8 true BR112014016632A8 (pt) | 2017-07-04 |
Family
ID=47630451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014016632A BR112014016632A8 (pt) | 2012-01-04 | 2013-01-03 | uso terapêutico de derivados de imidazopiridina |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US9732078B2 (pt) |
| EP (1) | EP2800566B1 (pt) |
| JP (1) | JP6067032B2 (pt) |
| KR (1) | KR102046196B1 (pt) |
| CN (1) | CN104144687B (pt) |
| AU (1) | AU2013207082B2 (pt) |
| BR (1) | BR112014016632A8 (pt) |
| CA (1) | CA2860413C (pt) |
| CL (1) | CL2014001784A1 (pt) |
| CO (1) | CO7020916A2 (pt) |
| EA (1) | EA027058B1 (pt) |
| ES (1) | ES2560619T3 (pt) |
| FR (1) | FR2985185B1 (pt) |
| HK (1) | HK1198690A1 (pt) |
| IL (1) | IL233493A (pt) |
| MA (1) | MA35878B1 (pt) |
| MX (1) | MX336340B (pt) |
| PH (1) | PH12014501537A1 (pt) |
| PL (1) | PL2800566T3 (pt) |
| SG (1) | SG11201403793UA (pt) |
| TW (1) | TWI557122B (pt) |
| UY (1) | UY34564A (pt) |
| WO (1) | WO2013102860A1 (pt) |
| ZA (1) | ZA201404928B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019011116A (es) * | 2017-03-22 | 2020-02-05 | Liao Xibin | Inhibidores de la tirosina quinasa de bruton. |
| CN115490687B (zh) * | 2022-09-19 | 2023-10-27 | 国家烟草质量监督检验中心 | 3-苯并呋喃基硫咪唑并吡啶衍生物及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2859997B1 (fr) | 2003-09-18 | 2006-02-03 | Sanofi Synthelabo | Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant. |
| FR2883286B1 (fr) * | 2005-03-16 | 2008-10-03 | Sanofi Aventis Sa | NOUVEAUX DERIVES D'IMIDAZO[1,5-a]PYRIDINES, INHIBITEURS DE FGFs, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT |
| FR2896247B1 (fr) | 2006-01-13 | 2008-02-29 | Sanofi Aventis Sa | Composes dimeres agonistes des recepteurs des fgfs (fgfrs), leur procede de preparation et leur application en therapeutique |
| EP1891955A1 (en) | 2006-07-24 | 2008-02-27 | Sanofi-Aventis | Use of 1,2,3-substituted indolizine derivatives, inhibitors of FGFs, for the preparation of a medicament intended for the treatment of degenerative joint diseases |
| CN1887878A (zh) | 2006-07-26 | 2007-01-03 | 浙江大学 | 三嗪氮氧化物及合成方法和用途 |
| FR2962437B1 (fr) | 2010-07-06 | 2012-08-17 | Sanofi Aventis | Derives d'imidazopyridine, leur procede de preparation et leur application en therapeutique |
-
2012
- 2012-01-04 FR FR1250075A patent/FR2985185B1/fr not_active Expired - Fee Related
-
2013
- 2013-01-03 CA CA2860413A patent/CA2860413C/en active Active
- 2013-01-03 WO PCT/IB2013/050048 patent/WO2013102860A1/en active Application Filing
- 2013-01-03 BR BR112014016632A patent/BR112014016632A8/pt not_active Application Discontinuation
- 2013-01-03 AU AU2013207082A patent/AU2013207082B2/en active Active
- 2013-01-03 SG SG11201403793UA patent/SG11201403793UA/en unknown
- 2013-01-03 PL PL13702101T patent/PL2800566T3/pl unknown
- 2013-01-03 JP JP2014550790A patent/JP6067032B2/ja active Active
- 2013-01-03 ES ES13702101.0T patent/ES2560619T3/es active Active
- 2013-01-03 EP EP13702101.0A patent/EP2800566B1/en active Active
- 2013-01-03 US US14/370,462 patent/US9732078B2/en active Active
- 2013-01-03 EA EA201491307A patent/EA027058B1/ru not_active IP Right Cessation
- 2013-01-03 MX MX2014008244A patent/MX336340B/es unknown
- 2013-01-03 CN CN201380012217.8A patent/CN104144687B/zh active Active
- 2013-01-03 KR KR1020147021454A patent/KR102046196B1/ko active IP Right Grant
- 2013-01-04 UY UY0001034564A patent/UY34564A/es not_active Application Discontinuation
- 2013-01-04 TW TW102100344A patent/TWI557122B/zh active
-
2014
- 2014-07-02 IL IL233493A patent/IL233493A/en active IP Right Grant
- 2014-07-03 PH PH12014501537A patent/PH12014501537A1/en unknown
- 2014-07-03 CL CL2014001784A patent/CL2014001784A1/es unknown
- 2014-07-04 ZA ZA2014/04928A patent/ZA201404928B/en unknown
- 2014-07-23 MA MA37231A patent/MA35878B1/fr unknown
- 2014-07-28 CO CO14163266A patent/CO7020916A2/es unknown
- 2014-12-02 HK HK14112128.4A patent/HK1198690A1/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |