BR112014015003A2 - composição farmacêutica, método para tratar um cancer e método para reduzir o tamanho de uma massa tumoral - Google Patents
composição farmacêutica, método para tratar um cancer e método para reduzir o tamanho de uma massa tumoralInfo
- Publication number
- BR112014015003A2 BR112014015003A2 BR112014015003A BR112014015003A BR112014015003A2 BR 112014015003 A2 BR112014015003 A2 BR 112014015003A2 BR 112014015003 A BR112014015003 A BR 112014015003A BR 112014015003 A BR112014015003 A BR 112014015003A BR 112014015003 A2 BR112014015003 A2 BR 112014015003A2
- Authority
- BR
- Brazil
- Prior art keywords
- reducing
- size
- pharmaceutical composition
- treating cancer
- tumor mass
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/329,897 US8501678B2 (en) | 2007-03-06 | 2011-12-19 | Variant activin receptor polypeptides and uses thereof |
PCT/US2012/070571 WO2013106175A1 (en) | 2011-12-19 | 2012-12-19 | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014015003A2 true BR112014015003A2 (pt) | 2019-09-24 |
Family
ID=47501527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014015003A BR112014015003A2 (pt) | 2011-12-19 | 2012-12-19 | composição farmacêutica, método para tratar um cancer e método para reduzir o tamanho de uma massa tumoral |
Country Status (21)
Country | Link |
---|---|
US (1) | US9610327B2 (pt) |
EP (1) | EP2793925B1 (pt) |
JP (3) | JP6145112B2 (pt) |
KR (1) | KR20140108562A (pt) |
CN (1) | CN104379159A (pt) |
AU (2) | AU2012364736A1 (pt) |
BR (1) | BR112014015003A2 (pt) |
CA (1) | CA2859504A1 (pt) |
CL (1) | CL2014001648A1 (pt) |
CO (1) | CO7101190A2 (pt) |
CR (1) | CR20140304A (pt) |
EA (1) | EA201491231A8 (pt) |
HK (1) | HK1203384A1 (pt) |
IL (1) | IL233178A0 (pt) |
MA (1) | MA35873B1 (pt) |
MX (1) | MX358358B (pt) |
PE (1) | PE20142114A1 (pt) |
PH (1) | PH12014501385A1 (pt) |
SG (2) | SG10201605027XA (pt) |
TN (1) | TN2014000270A1 (pt) |
WO (1) | WO2013106175A1 (pt) |
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CN105001320A (zh) | 2005-11-23 | 2015-10-28 | 阿塞勒隆制药公司 | Activin-ActRIIa拮抗剂及其促进骨骼生长的应用 |
US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
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KR20140137463A (ko) | 2007-02-01 | 2014-12-02 | 악셀레론 파마 인코포레이티드 | 액티빈-actrⅱa 길항제 및 유방암을 치료 또는 예방하기 위한 이들의 용도 |
TW201803890A (zh) | 2007-02-02 | 2018-02-01 | 艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
TWI606062B (zh) | 2007-02-09 | 2017-11-21 | 艾瑟勒朗法瑪公司 | 包含ActRIIa-Fc融合蛋白的醫藥組合物;ActRIIa-Fc融合蛋白於治療或預防與癌症相關的骨質流失之用途;ActRIIa-Fc融合蛋白於治療或預防多發性骨髓瘤之用途 |
TWI454479B (zh) | 2007-03-06 | 2014-10-01 | Amgen Inc | 變異之活動素受體多肽及其用途 |
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CA2962197C (en) * | 2014-04-18 | 2023-10-03 | Ravindra Kumar | Methods for increasing red blood cell levels and treating sickle-cell disease |
BR112016029226A2 (pt) | 2014-06-13 | 2017-10-17 | Acceleron Pharma Inc | métodos e composições para o tratamento de úlceras |
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EP2802308A1 (en) | 2012-01-13 | 2014-11-19 | Allergan, Inc. | Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation |
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2012
- 2012-12-19 CA CA2859504A patent/CA2859504A1/en not_active Abandoned
- 2012-12-19 BR BR112014015003A patent/BR112014015003A2/pt not_active IP Right Cessation
- 2012-12-19 WO PCT/US2012/070571 patent/WO2013106175A1/en active Application Filing
- 2012-12-19 CN CN201280070103.4A patent/CN104379159A/zh active Pending
- 2012-12-19 PE PE2014001002A patent/PE20142114A1/es not_active Application Discontinuation
- 2012-12-19 MX MX2014007483A patent/MX358358B/es active IP Right Grant
- 2012-12-19 JP JP2014548827A patent/JP6145112B2/ja active Active
- 2012-12-19 EP EP12809999.1A patent/EP2793925B1/en active Active
- 2012-12-19 EA EA201491231A patent/EA201491231A8/ru unknown
- 2012-12-19 KR KR1020147020285A patent/KR20140108562A/ko not_active Application Discontinuation
- 2012-12-19 US US14/366,978 patent/US9610327B2/en active Active
- 2012-12-19 SG SG10201605027XA patent/SG10201605027XA/en unknown
- 2012-12-19 AU AU2012364736A patent/AU2012364736A1/en not_active Abandoned
- 2012-12-19 SG SG11201403367YA patent/SG11201403367YA/en unknown
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2014
- 2014-06-16 IL IL233178A patent/IL233178A0/en unknown
- 2014-06-18 PH PH12014501385A patent/PH12014501385A1/en unknown
- 2014-06-18 TN TNP2014000270A patent/TN2014000270A1/en unknown
- 2014-06-19 CL CL2014001648A patent/CL2014001648A1/es unknown
- 2014-06-23 CR CR20140304A patent/CR20140304A/es unknown
- 2014-07-03 CO CO14143018A patent/CO7101190A2/es unknown
- 2014-07-18 MA MA37223A patent/MA35873B1/fr unknown
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2015
- 2015-04-24 HK HK15103990.7A patent/HK1203384A1/xx unknown
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2017
- 2017-05-12 JP JP2017095155A patent/JP6358633B2/ja active Active
- 2017-10-18 AU AU2017248486A patent/AU2017248486B2/en active Active
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2018
- 2018-06-13 JP JP2018112592A patent/JP6542433B2/ja active Active
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