BR112014007580A2 - dispositivo médico de intervenção e método de fabricação do mesmo - Google Patents
dispositivo médico de intervenção e método de fabricação do mesmoInfo
- Publication number
- BR112014007580A2 BR112014007580A2 BR112014007580A BR112014007580A BR112014007580A2 BR 112014007580 A2 BR112014007580 A2 BR 112014007580A2 BR 112014007580 A BR112014007580 A BR 112014007580A BR 112014007580 A BR112014007580 A BR 112014007580A BR 112014007580 A2 BR112014007580 A2 BR 112014007580A2
- Authority
- BR
- Brazil
- Prior art keywords
- proliferation
- drug
- intimal
- adventitious
- suppression
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/146—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/02—Methods for coating medical devices
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Materials For Medical Uses (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
Abstract
resumo dispositivo médico de intervenção e método de fabricação do mesmo, compreendendo: um corpo de stent (1); uma superfície do corpo de stent (1) contendo uma estrutura de liberação de fármacos (3), e os fármacos na estrutura de liberação de fármacos (3), sendo um fármaco utilizado para supressão da proliferação de fibroblastos adventícios e um fármaco para supressão da proliferação de células musculares intimais e/ou lisas. em uso, depois de o dispositivo médico intervencionista ser implantado no corpo humano, o medicamento para supressão da proliferação de fibroblastos adventícios é carregado para poder promover a expansão compensatória do vaso, e o fármaco para supressão da proliferação de células musculares intimais e/ou lisas carregados também podem suprimir a proliferação intimal do vaso. a combinação dos dois tipos de fármacos reduz signifcativamente a taxa de ocorrência de reestenose intra-stent.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2011102953249A CN102499798A (zh) | 2011-09-29 | 2011-09-29 | 一种介入医疗器械及其制备方法 |
PCT/CN2012/070400 WO2013044603A1 (zh) | 2011-09-29 | 2012-01-16 | 一种介入医疗器械及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014007580A2 true BR112014007580A2 (pt) | 2017-04-11 |
Family
ID=46211977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014007580A BR112014007580A2 (pt) | 2011-09-29 | 2012-01-16 | dispositivo médico de intervenção e método de fabricação do mesmo |
Country Status (7)
Country | Link |
---|---|
US (2) | US20140248327A1 (pt) |
EP (1) | EP2762110A4 (pt) |
JP (1) | JP2014530058A (pt) |
CN (1) | CN102499798A (pt) |
BR (1) | BR112014007580A2 (pt) |
IN (1) | IN2014CN02578A (pt) |
WO (1) | WO2013044603A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102397119A (zh) * | 2011-09-29 | 2012-04-04 | 微创医疗器械(上海)有限公司 | 一种介入医疗器械及其制备方法 |
US10232077B2 (en) * | 2014-10-06 | 2019-03-19 | Gatt Technologies B.V. | Tissue-adhesive porous haemostatic product |
DE112014007192T5 (de) * | 2014-12-25 | 2017-08-24 | Olympus Corporation | Osteosynthetisches Implantat und Herstellungsverfahren hierfür |
CN105816921A (zh) * | 2016-04-20 | 2016-08-03 | 山东百多安医用材料改性工程技术中心 | 一种仿生血管支架及其制备方法 |
CN106512188A (zh) * | 2016-12-13 | 2017-03-22 | 天津飞捷科技有限公司 | 机电一体化靶向药物释放介入类医疗器械及其制备方法 |
CN109602523B (zh) * | 2019-01-03 | 2024-02-09 | 科塞尔医疗科技(苏州)有限公司 | 一种可回收的药物支架 |
CN110283296B (zh) * | 2019-06-20 | 2020-07-31 | 中国科学院长春应用化学研究所 | 双功能聚氨酯及其制备方法与应用 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6273913B1 (en) * | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
US6908624B2 (en) * | 1999-12-23 | 2005-06-21 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
WO2003034944A1 (de) * | 2001-10-15 | 2003-05-01 | Hemoteq Gmbh | Beschichtung von stents zur verhinderung von restenose |
EP1308179A1 (en) * | 2001-10-30 | 2003-05-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Improved endoprosthetic device |
US20050019404A1 (en) * | 2003-06-30 | 2005-01-27 | Hsing-Wen Sung | Drug-eluting biodegradable stent |
JP4588986B2 (ja) * | 2002-08-20 | 2010-12-01 | テルモ株式会社 | 体内埋込医療器具 |
WO2004075884A1 (en) | 2003-02-28 | 2004-09-10 | Howard Florey Institute Of Experimental Physiology And Medicine | Therapeutic compositions |
US7488343B2 (en) * | 2003-09-16 | 2009-02-10 | Boston Scientific Scimed, Inc. | Medical devices |
US20070219613A1 (en) | 2003-10-06 | 2007-09-20 | Xtent, Inc. | Apparatus and methods for interlocking stent segments |
US8003122B2 (en) | 2004-03-31 | 2011-08-23 | Cordis Corporation | Device for local and/or regional delivery employing liquid formulations of therapeutic agents |
US20050266040A1 (en) * | 2004-05-28 | 2005-12-01 | Brent Gerberding | Medical devices composed of porous metallic materials for delivering biologically active materials |
JP4982369B2 (ja) * | 2004-08-13 | 2012-07-25 | ラトガース,ザ ステート ユニバーシティ | 放射線不透過性の高分子ステント |
US20060199876A1 (en) * | 2005-03-04 | 2006-09-07 | The University Of British Columbia | Bioceramic composite coatings and process for making same |
US20070224235A1 (en) * | 2006-03-24 | 2007-09-27 | Barron Tenney | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
US8187620B2 (en) * | 2006-03-27 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents |
US20070292470A1 (en) * | 2006-06-15 | 2007-12-20 | Medtronic Vascular, Inc. | Implantable Medical Devices and Methods for Making the Same |
CN102258811B (zh) * | 2006-07-03 | 2015-03-11 | 汉莫堤克股份有限公司 | 持久使血管开的活性物释放医药产品的制造、方法和使用 |
CN100493627C (zh) * | 2006-10-20 | 2009-06-03 | 东南大学 | 冠状动脉药物涂层支架 |
CN101199873B (zh) * | 2006-12-14 | 2013-06-19 | 乐普(北京)医疗器械股份有限公司 | 药物洗脱器械用纳米级孔洞药物释放结构及其制备方法 |
US8187255B2 (en) * | 2007-02-02 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
WO2008112458A2 (en) * | 2007-03-09 | 2008-09-18 | Icon Medical Corp | Bioabsorbable coatings for medical devices |
CN101318032B (zh) | 2007-06-06 | 2012-11-21 | 李京倖 | 小口径组织工程学人工血管及其制备方法 |
US20090018646A1 (en) * | 2007-07-10 | 2009-01-15 | Zhao Jonathon Z | Coating Employing an Anti-Thrombotic Conjugate |
CN101406713B (zh) * | 2007-10-12 | 2012-09-19 | 微创医疗器械(上海)有限公司 | 一种人工血管支架及其制备方法 |
CN101945621B (zh) * | 2007-12-18 | 2014-06-18 | 因特尔赛克特耳鼻喉公司 | 自扩展装置及用于其的方法 |
KR100947094B1 (ko) * | 2008-01-02 | 2010-03-10 | 주식회사 디오 | 의료용 스텐트 및 그 제조방법 |
JP5530361B2 (ja) | 2008-09-17 | 2014-06-25 | テルモ株式会社 | ステント |
US20100280600A1 (en) * | 2009-04-30 | 2010-11-04 | Vipul Bhupendra Dave | Dual drug stent |
CN101879102B (zh) * | 2009-05-07 | 2014-07-09 | 上海微创医疗器械(集团)有限公司 | 一种凹槽携载式涂层可降解型药物洗脱支架 |
CN102397119A (zh) | 2011-09-29 | 2012-04-04 | 微创医疗器械(上海)有限公司 | 一种介入医疗器械及其制备方法 |
-
2011
- 2011-09-29 CN CN2011102953249A patent/CN102499798A/zh active Pending
-
2012
- 2012-01-16 EP EP12834752.3A patent/EP2762110A4/en not_active Withdrawn
- 2012-01-16 WO PCT/CN2012/070400 patent/WO2013044603A1/zh active Application Filing
- 2012-01-16 BR BR112014007580A patent/BR112014007580A2/pt not_active IP Right Cessation
- 2012-01-16 JP JP2014532219A patent/JP2014530058A/ja active Pending
- 2012-01-16 IN IN2578CHN2014 patent/IN2014CN02578A/en unknown
- 2012-01-16 US US14/348,857 patent/US20140248327A1/en not_active Abandoned
-
2015
- 2015-04-02 US US14/677,741 patent/US9433709B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US9433709B2 (en) | 2016-09-06 |
CN102499798A (zh) | 2012-06-20 |
US20150209485A1 (en) | 2015-07-30 |
WO2013044603A1 (zh) | 2013-04-04 |
EP2762110A4 (en) | 2015-05-06 |
EP2762110A1 (en) | 2014-08-06 |
US20140248327A1 (en) | 2014-09-04 |
JP2014530058A (ja) | 2014-11-17 |
IN2014CN02578A (pt) | 2015-08-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |