BR112014005505A2 - substrato de polinucleotídeo isolado para uma enzima de ácido nucleico catalítica, método para detectar a presença de pelo menos um alvo, uso do substrato de polinucleotídeo isolado e kit - Google Patents
substrato de polinucleotídeo isolado para uma enzima de ácido nucleico catalítica, método para detectar a presença de pelo menos um alvo, uso do substrato de polinucleotídeo isolado e kitInfo
- Publication number
- BR112014005505A2 BR112014005505A2 BR112014005505A BR112014005505A BR112014005505A2 BR 112014005505 A2 BR112014005505 A2 BR 112014005505A2 BR 112014005505 A BR112014005505 A BR 112014005505A BR 112014005505 A BR112014005505 A BR 112014005505A BR 112014005505 A2 BR112014005505 A2 BR 112014005505A2
- Authority
- BR
- Brazil
- Prior art keywords
- isolated polynucleotide
- polynucleotide substrate
- kit
- target
- detecting
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 title 2
- 108091033319 polynucleotide Proteins 0.000 title 2
- 239000002157 polynucleotide Substances 0.000 title 2
- 239000000758 substrate Substances 0.000 title 2
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 230000003197 catalytic effect Effects 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
- C12N2320/11—Applications; Uses in screening processes for the determination of target sites, i.e. of active nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2011903686 | 2011-09-09 | ||
| AU2011903686A AU2011903686A0 (en) | 2011-09-09 | Nucleic acid enzyme substrates | |
| PCT/AU2012/001081 WO2013033792A1 (en) | 2011-09-09 | 2012-09-10 | Nucleic acid enzyme substrates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014005505A2 true BR112014005505A2 (pt) | 2017-04-04 |
| BR112014005505B1 BR112014005505B1 (pt) | 2021-01-12 |
Family
ID=47831377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014005505-0A BR112014005505B1 (pt) | 2011-09-09 | 2012-09-10 | substrato de polinucleotídeo isolado para uma enzima de ácido nucleico multi-componente (mnazima) ou dnazima, método para detectar a presença de pelo menos um alvo, kit e montagem |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9506108B2 (pt) |
| EP (1) | EP2753717B1 (pt) |
| JP (2) | JP2014531203A (pt) |
| KR (1) | KR102044564B1 (pt) |
| CN (1) | CN103917664B (pt) |
| BR (1) | BR112014005505B1 (pt) |
| CA (1) | CA2847697C (pt) |
| DK (1) | DK2753717T3 (pt) |
| ES (1) | ES2698053T3 (pt) |
| IL (1) | IL231319B (pt) |
| MX (1) | MX349801B (pt) |
| RU (1) | RU2650806C2 (pt) |
| SG (1) | SG11201400464QA (pt) |
| WO (1) | WO2013033792A1 (pt) |
| ZA (1) | ZA201402046B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014531203A (ja) | 2011-09-09 | 2014-11-27 | スピーデクス ピーティーワイ リミテッド | 核酸酵素基質 |
| AU2013202354A1 (en) * | 2012-06-18 | 2014-01-16 | Speedx Pty Ltd | Target detection and signal amplification |
| WO2015187786A2 (en) * | 2014-06-03 | 2015-12-10 | Helix Nanotechnologies, Inc. | Programmable nucleotide enzymes |
| CN104328192B (zh) * | 2014-11-05 | 2021-03-30 | 南京大学 | 核酶放大的高灵敏电化学免疫分析方法 |
| WO2016194823A1 (ja) * | 2015-05-29 | 2016-12-08 | 凸版印刷株式会社 | 核酸の検出方法、核酸の定量方法、核酸の塩基配列識別方法、核酸の変異又は多型の識別方法、核酸検出用キット、及び反応チップ |
| US20170044596A1 (en) * | 2015-07-17 | 2017-02-16 | Luminex Corporation | Methods and compositions for catalytic assays |
| CN107663530B (zh) * | 2017-11-10 | 2020-07-03 | 中国海洋大学 | 一种单链核酸检测试剂盒、方法及其应用 |
| US11629366B2 (en) * | 2018-03-01 | 2023-04-18 | Collin Frank MARINO | Method for selective translation of desired proteins in the presence of a specified nucleic acid ligand |
| US11976282B2 (en) | 2020-06-23 | 2024-05-07 | Qatar University | GATA3 inhibitors for the promotion of subcutaneous fat deposition |
| WO2022090521A1 (en) | 2020-10-29 | 2022-05-05 | Biocartis Nv | Generic cartridge and method for multiplex nucleic acid detection |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807718A (en) * | 1994-12-02 | 1998-09-15 | The Scripps Research Institute | Enzymatic DNA molecules |
| US7034009B2 (en) * | 1995-10-26 | 2006-04-25 | Sirna Therapeutics, Inc. | Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R) |
| CA2230203A1 (en) * | 1998-04-29 | 1999-10-29 | Universite De Sherbrooke | Delta ribozyme for rna cleavage |
| US7485419B2 (en) * | 2004-01-13 | 2009-02-03 | The Board Of Trustees Of The University Of Illinois | Biosensors based on directed assembly of particles |
| DK2385141T3 (da) * | 2005-10-07 | 2013-10-28 | Speedx Pty Ltd | Flerkomponentnukleinsyreenzymer og fremgangsmåder til anvendelse heraf |
| CN101341260B (zh) * | 2005-10-07 | 2014-02-12 | 强生研究有限公司 | 多组分核酸酶及其使用方法 |
| ZA200901742B (en) | 2006-10-06 | 2010-06-30 | Johnson & Johnson Res Pty Ltd | Moleculor switches and methods for their use |
| WO2008122084A1 (en) | 2007-04-05 | 2008-10-16 | Johnson & Johnson Research Pty Limited | Nucleic acid enzymes and complexes and methods for their use |
| JP2014531203A (ja) | 2011-09-09 | 2014-11-27 | スピーデクス ピーティーワイ リミテッド | 核酸酵素基質 |
| US9963738B2 (en) * | 2012-02-20 | 2018-05-08 | Speedx Pty Ltd | Detection of nucleic acids |
| AU2013202354A1 (en) | 2012-06-18 | 2014-01-16 | Speedx Pty Ltd | Target detection and signal amplification |
-
2012
- 2012-09-10 JP JP2014528802A patent/JP2014531203A/ja active Pending
- 2012-09-10 BR BR112014005505-0A patent/BR112014005505B1/pt active IP Right Grant
- 2012-09-10 EP EP12830774.1A patent/EP2753717B1/en active Active
- 2012-09-10 RU RU2014110960A patent/RU2650806C2/ru active
- 2012-09-10 WO PCT/AU2012/001081 patent/WO2013033792A1/en active Application Filing
- 2012-09-10 US US14/343,840 patent/US9506108B2/en active Active
- 2012-09-10 CA CA2847697A patent/CA2847697C/en active Active
- 2012-09-10 SG SG11201400464QA patent/SG11201400464QA/en unknown
- 2012-09-10 MX MX2014002741A patent/MX349801B/es active IP Right Grant
- 2012-09-10 DK DK12830774.1T patent/DK2753717T3/en active
- 2012-09-10 ES ES12830774T patent/ES2698053T3/es active Active
- 2012-09-10 CN CN201280046444.8A patent/CN103917664B/zh active Active
- 2012-09-10 KR KR1020147007268A patent/KR102044564B1/ko active IP Right Grant
-
2014
- 2014-03-05 IL IL231319A patent/IL231319B/en active IP Right Grant
- 2014-03-20 ZA ZA2014/02046A patent/ZA201402046B/en unknown
-
2016
- 2016-10-31 US US15/339,846 patent/US10273526B2/en active Active
-
2018
- 2018-01-26 JP JP2018011601A patent/JP6641397B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL231319A0 (en) | 2014-04-30 |
| CN103917664B (zh) | 2018-06-15 |
| JP6641397B2 (ja) | 2020-02-05 |
| MX2014002741A (es) | 2014-07-30 |
| US10273526B2 (en) | 2019-04-30 |
| SG11201400464QA (en) | 2014-06-27 |
| US9506108B2 (en) | 2016-11-29 |
| ES2698053T3 (es) | 2019-01-30 |
| WO2013033792A1 (en) | 2013-03-14 |
| CN103917664A (zh) | 2014-07-09 |
| ZA201402046B (en) | 2015-06-24 |
| IL231319B (en) | 2019-06-30 |
| EP2753717A1 (en) | 2014-07-16 |
| KR102044564B1 (ko) | 2019-11-13 |
| CA2847697C (en) | 2020-04-21 |
| RU2014110960A (ru) | 2015-10-20 |
| DK2753717T3 (en) | 2018-12-17 |
| EP2753717B1 (en) | 2018-10-31 |
| KR20140068992A (ko) | 2014-06-09 |
| CA2847697A1 (en) | 2013-03-14 |
| US20170114397A1 (en) | 2017-04-27 |
| JP2018078910A (ja) | 2018-05-24 |
| BR112014005505B1 (pt) | 2021-01-12 |
| JP2014531203A (ja) | 2014-11-27 |
| US20150050656A1 (en) | 2015-02-19 |
| NZ622016A (en) | 2016-03-31 |
| MX349801B (es) | 2017-08-14 |
| EP2753717A4 (en) | 2015-06-24 |
| RU2650806C2 (ru) | 2018-04-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112014005505A2 (pt) | substrato de polinucleotídeo isolado para uma enzima de ácido nucleico catalítica, método para detectar a presença de pelo menos um alvo, uso do substrato de polinucleotídeo isolado e kit | |
| HK1246360A1 (zh) | 用於蛋白質和核酸的超高靈敏度測量的方法和試劑盒以及新型酶底物 | |
| HK1249143A1 (zh) | 靶核酸的檢測方法 | |
| GB2487632B (en) | Methods,compositions,and kits for determining the presence/absence of a variant nucleic acid sequence | |
| WO2012134602A3 (en) | Methods and systems for sequencing long nucleic acids | |
| EP2746395A4 (en) | PRIMER SET, METHOD FOR AMPLIFYING TARGET NUCLEIC ACID SEQUENCE USING THE SAME, AND METHOD FOR DETECTING NUCLEIC ACID MUTRED USING THE SAME | |
| BR112014000443A2 (pt) | métodos e ácidos nucléicos para determinação do prognóstico de um indivíduo com câncer | |
| BR112014020422A2 (pt) | método para determinar a presença ou ausência de um polinucleotídeo alvo em uma amostra, oligonucleotídeo iniciador isolado ou partzime, duplex de ácido nucleico de cadeia dupla isolado, enzima de ácido nucleico multi-componente, complexo de ácido nucleico, uso da mnazyme e kit | |
| HK1198548A1 (en) | Methods and compositions for detecting target nucleic acids | |
| BR112013013471A2 (pt) | sistema de painel solar, kit de painel solar e método para determinar um estado operacional de um painel solar | |
| BR112014002616A2 (pt) | método para detectar cãncer pancreático e reagente ou kit para detectar câncer pancreático | |
| BR112013029967A2 (pt) | método para a integração simultânea de duas ou mais cópias de um polinucleotídeo de interesse no cromossomo de uma célula hospedeira fúngica | |
| EP2770090A4 (en) | METHOD FOR PRODUCING A NUCLEIC ACID LIBRARY AND USES THEREOF AND KITS THEREFOR | |
| EP2615457A4 (en) | REAGENT COMPOSITION FOR NUCLEIC ACID CHROMATOGRAPHY OR IMMUNCHROMATOGRAPHY, METHOD FOR MEASURING BY NUCLEIC ACID CHROMATOGRAPHY OR IMMUNCHROMATOGRAPHY, AND KIT FOR MEASURES BY NUCLEIC ACID CHROMATOGRAPHY OR IMMUNCHROMATOGRAPHY | |
| BR112014001258A2 (pt) | método de tipagem de dna, e, conjuntos de iniciadores para tipagem de dna | |
| SG11201400635UA (en) | Method for detecting target nucleic acid | |
| EP3134550A4 (en) | High-throughput structure determination using nucleic acid calipers | |
| BR112014024421A2 (pt) | métodos de preparação de amostras para amplificação de ácido nucleico | |
| BR112013016704A2 (pt) | método para imobilizar os ligandos nucléicos. | |
| WO2012174378A3 (en) | Methods and materials for assessing allelic imbalance | |
| BR112014029274A2 (pt) | anticorpo isolado, composição farmacêutica, uso do anticorpo, método para tratar infecção rábica, kit para tratar infecção rábica, kit para detectar vírus rábico, ácido nucleico isolado, e, célula hospedeira. | |
| DK2536845T3 (da) | Oligonucleotidbaseret fremgangsmåde til detektion af analyt | |
| EP2722388A4 (en) | NUCLEIC ACID PROBE FOR THE ASSAY OF NUCLEIC ACIDS | |
| EP2873731A4 (en) | NUCLEIC ACID ENGINE, METHOD FOR THE DESIGN OF THE NUCLEIC ACID END AND METHOD FOR DETERMINING TARGET SEQUENCES | |
| EP3378948A4 (en) | METHOD FOR QUANTIFYING TARGET NUCLEIC ACID AND KIT THEREOF |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/09/2012, OBSERVADAS AS CONDICOES LEGAIS. |