BR112013025957A2 - métodos e composições para regeneração de ossos e cartilagens através de autoenxerto de células tronco pluripotentes do tipo embriônica muito pequenas de humanos adultos (hvsels) - Google Patents
métodos e composições para regeneração de ossos e cartilagens através de autoenxerto de células tronco pluripotentes do tipo embriônica muito pequenas de humanos adultos (hvsels)Info
- Publication number
- BR112013025957A2 BR112013025957A2 BR112013025957A BR112013025957A BR112013025957A2 BR 112013025957 A2 BR112013025957 A2 BR 112013025957A2 BR 112013025957 A BR112013025957 A BR 112013025957A BR 112013025957 A BR112013025957 A BR 112013025957A BR 112013025957 A2 BR112013025957 A2 BR 112013025957A2
- Authority
- BR
- Brazil
- Prior art keywords
- hvsels
- autograft
- bone
- compositions
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3847—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3852—Cartilage, e.g. meniscus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Organic Chemistry (AREA)
- Botany (AREA)
- Physical Education & Sports Medicine (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Molecular Biology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161473420P | 2011-04-08 | 2011-04-08 | |
PCT/US2012/032807 WO2012139131A1 (en) | 2011-04-08 | 2012-04-09 | Autologous human adult pluripotent very small embryonic-like (hvsel) stem cell regeneration of bone and cartilage |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013025957A2 true BR112013025957A2 (pt) | 2016-09-20 |
Family
ID=46969593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013025957A BR112013025957A2 (pt) | 2011-04-08 | 2012-04-09 | métodos e composições para regeneração de ossos e cartilagens através de autoenxerto de células tronco pluripotentes do tipo embriônica muito pequenas de humanos adultos (hvsels) |
Country Status (9)
Country | Link |
---|---|
US (1) | US20140112891A1 (pt) |
EP (1) | EP2694641A4 (pt) |
JP (1) | JP2014511864A (pt) |
CN (1) | CN103748215A (pt) |
AU (1) | AU2012239874A1 (pt) |
BR (1) | BR112013025957A2 (pt) |
CA (1) | CA2832592A1 (pt) |
RU (1) | RU2013147265A (pt) |
WO (1) | WO2012139131A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2015520174A (ja) * | 2012-05-31 | 2015-07-16 | ネオステム,インコーポレイティド | 眼疾患を治療するためのヒト極小胚様(vsel)幹細胞 |
WO2014089268A2 (en) | 2012-12-06 | 2014-06-12 | StemBios Technologies, Inc. | Lgr5+ somatic stem cells |
US20160008506A1 (en) * | 2013-03-07 | 2016-01-14 | Neostem, Inc. | Stem cell compositions and methods for would healing |
JP2018501189A (ja) * | 2014-11-19 | 2018-01-18 | ステムバイオス テクノロジーズ,インコーポレイテッド | 骨欠損を治療するための体性幹細胞 |
CN106106443A (zh) * | 2016-06-23 | 2016-11-16 | 松桃如阿雅观光农业产业开发有限公司 | 红肉蜜柚防治病虫害药剂 |
CN114732962B (zh) * | 2022-05-20 | 2023-06-20 | 武汉理工大学 | 一种可降解的抗菌引导骨再生膜及其制备方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009059032A2 (en) * | 2007-10-30 | 2009-05-07 | University Of Louisville Research Foundation, Inc. | Uses and isolation of very small embryonic-like (vsel) stem cells |
EP1974018A4 (en) * | 2005-12-08 | 2010-01-27 | Univ Louisville Res Found | VSEL (VERY SMALL EMBRYONIC LIKE) STEM CELLS AND METHOD OF ISOLATING AND USE THEREOF |
DK1989295T3 (da) * | 2006-02-16 | 2020-09-28 | Univ Bruxelles | Fremgangsmåde til osteogen differentiering af knoglemarv-stamceller (bmsc) og anvendelser deraf |
US8574567B2 (en) * | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
CN102046188A (zh) * | 2008-03-27 | 2011-05-04 | 尼奥斯泰姆公司 | 在皮肤伤口愈合中使用干细胞的组合物和方法 |
CN102333861A (zh) * | 2008-09-30 | 2012-01-25 | 路易斯维尔大学研究基金会有限公司 | 用于分离非常小的胚胎样(vsel)干细胞的方法 |
-
2012
- 2012-04-09 AU AU2012239874A patent/AU2012239874A1/en not_active Abandoned
- 2012-04-09 RU RU2013147265/10A patent/RU2013147265A/ru not_active Application Discontinuation
- 2012-04-09 BR BR112013025957A patent/BR112013025957A2/pt not_active IP Right Cessation
- 2012-04-09 CA CA2832592A patent/CA2832592A1/en not_active Abandoned
- 2012-04-09 WO PCT/US2012/032807 patent/WO2012139131A1/en active Application Filing
- 2012-04-09 EP EP12767342.4A patent/EP2694641A4/en not_active Withdrawn
- 2012-04-09 CN CN201280027627.5A patent/CN103748215A/zh active Pending
- 2012-04-09 US US14/110,230 patent/US20140112891A1/en not_active Abandoned
- 2012-04-09 JP JP2014504077A patent/JP2014511864A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20140112891A1 (en) | 2014-04-24 |
AU2012239874A1 (en) | 2013-10-31 |
CN103748215A (zh) | 2014-04-23 |
CA2832592A1 (en) | 2012-10-11 |
WO2012139131A1 (en) | 2012-10-11 |
RU2013147265A (ru) | 2015-05-20 |
JP2014511864A (ja) | 2014-05-19 |
EP2694641A1 (en) | 2014-02-12 |
EP2694641A4 (en) | 2014-11-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA201708538B (en) | Methods for purifying cells derived from pluripotent stem cells | |
HK1217917A1 (zh) | 由多能幹細胞製備血小板的方法及其組合物 | |
HK1250885A1 (zh) | 冷凍保存來源於多能幹細胞的組織的方法 | |
DK3008172T3 (da) | Dyrkningsmedium-sammensætninger til modning af cardiomyocytter afledt fra pluripotente mammale stamceller | |
BR112013025957A2 (pt) | métodos e composições para regeneração de ossos e cartilagens através de autoenxerto de células tronco pluripotentes do tipo embriônica muito pequenas de humanos adultos (hvsels) | |
DK2938722T3 (da) | Suspension og klyngedannelse af humane pluripotente celler til differentiering til endokrine pankreasceller | |
DK2938723T3 (da) | Differentiering af humane embryonale stamceller til pancreatiske endokrine celler under anvendelse af hb9-regulatorer | |
DK3039122T3 (da) | Generering af endokrine progenitorceller fra humane pluripotente stamceller under anvendelse af små molekyler | |
PL2683390T3 (pl) | Kompozycje i sposoby przeszczepiania mikrobioty okrężnicy | |
DK2727998T3 (da) | Fremgangsmåder til oprensning af pancreatiske endodermceller afledt fra humane embryoniske stamceller | |
EP2794860A4 (en) | METHOD OF INDUCING A DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS INTO INTERMEDIATE MESODERM CELLS | |
BR112013024467A2 (pt) | método e composições direcionadas para células adiposas em mamíferos | |
DK2488636T3 (da) | Fremgangsmåde til oprensning af adenoviruspartikler fra kulturer med høj celledensitet | |
BR112013024401A2 (pt) | métodos e composições para o tratamento do transtorno do déficit de atenção | |
CO6862102A2 (es) | Composiciones y métodos para transferencia de energía mitocondrial de línea germinal autóloga | |
BR112013017851A2 (pt) | método para reduzir níveis de colágeno de c-telopeptídeo do tipo ii | |
EP2683476A4 (en) | PHYLLOSILICATE BASE COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF TO CATALYTIC PYROLYSIS OF BIOMASS | |
SG11201505965TA (en) | Culture method for stable undifferentiated proliferation of pluripotent stem cells | |
CO6950485A2 (es) | Composiciones perfumantes y usos de las mismas | |
CO6950484A2 (es) | Composiciones perfumantes y usos de las mismas | |
CO6850301A1 (es) | Composiciones y métodos para mejorar la calidad del esperma procesado | |
CO6842021A2 (es) | Análogos de ácido epoxieicosatrienoico y métodos para elaborarlosy utilizarlos | |
EP2912166A4 (en) | METHOD FOR THE PRODUCTION OF PLURIPOTENTIAL STEM CELLS FROM CHONDROCYTES | |
GB2500161B (en) | Enhancement of allogeneic hematopoietic stem cell transplantation | |
BR112013012583A2 (pt) | composições de limpeza diluíveis e métodos para utilização |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |