BR112013023893A2 - mecanismo de ajuste e dispositivo de injeção de dose - Google Patents

mecanismo de ajuste e dispositivo de injeção de dose

Info

Publication number
BR112013023893A2
BR112013023893A2 BR112013023893A BR112013023893A BR112013023893A2 BR 112013023893 A2 BR112013023893 A2 BR 112013023893A2 BR 112013023893 A BR112013023893 A BR 112013023893A BR 112013023893 A BR112013023893 A BR 112013023893A BR 112013023893 A2 BR112013023893 A2 BR 112013023893A2
Authority
BR
Brazil
Prior art keywords
dose
injection device
adjustment mechanism
hitch
trigger component
Prior art date
Application number
BR112013023893A
Other languages
English (en)
Other versions
BR112013023893B1 (pt
Inventor
David Aubrey Plumptre
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of BR112013023893A2 publication Critical patent/BR112013023893A2/pt
Publication of BR112013023893B1 publication Critical patent/BR112013023893B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525Dosing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525Dosing
    • A61M5/31528Dosing by means of rotational movements, e.g. screw-thread mechanisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3155Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3155Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31555Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

resumo patente de invenção: "mecanismo de ajuste e dispositivo de injeção de dose". a presente invenção refere-se a um mecanismo de ajuste de dose (1) para um dispositivo de liberação de medicamento proporcionado, compreendendo: um elemento de ajuste de dose (3); um elemento acionador (4); um engate (5a, 5b); um primeiro componente de gatilho (6'); e um segundo componente de gatilho (6''). o primeiro engate (5a, 5b) e o segundo engate (9, 11) são projetados e adaptados entre si, de modo que, a qualquer momento durante a operação, o primeiro engate (5a, 5b) acopla rotativamente o elemento de ajuste de dose (3) e o elemento acionador (4), e/ou o segundo engate (9, 11) acopla rotativamente o elemento acionador (4) e o primeiro componente de gatilho (6'). além disso, a invenção se refere a um dispositivo de injeção com esse mecanismo de ajuste de dose.
BR112013023893-3A 2011-03-25 2012-03-22 mecanismo de ajuste e dispositivo de injeção de dose BR112013023893B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11159756.3 2011-03-25
EP11159756 2011-03-25
PCT/EP2012/055054 WO2012130703A1 (en) 2011-03-25 2012-03-22 Dose setting mechanism and injection device

Publications (2)

Publication Number Publication Date
BR112013023893A2 true BR112013023893A2 (pt) 2016-12-13
BR112013023893B1 BR112013023893B1 (pt) 2021-01-05

Family

ID=44367013

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013023893-3A BR112013023893B1 (pt) 2011-03-25 2012-03-22 mecanismo de ajuste e dispositivo de injeção de dose

Country Status (21)

Country Link
US (1) US9144649B2 (pt)
EP (1) EP2688614B1 (pt)
JP (1) JP6150788B2 (pt)
KR (1) KR101961085B1 (pt)
CN (1) CN103561801B (pt)
AR (1) AR085523A1 (pt)
AU (1) AU2012234467B2 (pt)
BR (1) BR112013023893B1 (pt)
CA (1) CA2830022C (pt)
DK (1) DK2688614T3 (pt)
ES (1) ES2534081T3 (pt)
HK (1) HK1189526A1 (pt)
IL (1) IL228253B (pt)
MX (1) MX336984B (pt)
MY (1) MY164000A (pt)
PT (1) PT2688614E (pt)
RU (1) RU2606451C2 (pt)
SG (1) SG193282A1 (pt)
TW (1) TWI600446B (pt)
WO (1) WO2012130703A1 (pt)
ZA (1) ZA201306582B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012127046A2 (en) 2011-03-24 2012-09-27 Sanofi-Aventis Deutschland Gmbh Device and method for detecting an actuation action performable with a medical device
EP3071265B1 (en) 2013-11-22 2023-04-26 Sanofi-Aventis Deutschland GmbH Spring assisted drug delivery device
JP6444219B2 (ja) * 2015-02-27 2018-12-26 Jxtgエネルギー株式会社 ギヤ油用潤滑油組成物
EP4316552A3 (en) 2015-06-09 2024-04-17 Sanofi-Aventis Deutschland GmbH Data collection apparatus for attachment to an injection device
US20170107417A1 (en) * 2015-06-30 2017-04-20 Exxonmobil Chemical Patents Inc. Lubricant Compositions and Methods of Making and Using Same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5279586A (en) * 1992-02-04 1994-01-18 Becton, Dickinson And Company Reusable medication delivery pen
US7195616B2 (en) * 2001-05-16 2007-03-27 Eli Lilly And Company Medication injector apparatus with drive assembly that facilitates reset
GB0304823D0 (en) * 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
US9205197B2 (en) * 2003-03-03 2015-12-08 Sanofi-Aventis Deutschland Gmbh Drug delivery device dose setting mechanism
ES2427146T3 (es) * 2004-10-04 2013-10-29 Sanofi-Aventis Deutschland Gmbh Mecanismo accionador para un dispositivo de descarga de fármacos
CA2663239C (en) * 2006-09-29 2015-03-31 Novo Nordisk A/S An injection device with electronic detecting means
US9623187B2 (en) 2009-06-01 2017-04-18 Sanofi-Aventis Deutschland Gmbh Resettable drug delivery device
US20120204662A1 (en) * 2009-06-30 2012-08-16 Sanofi-Aventis Deutschland Gmbh Drive Mechanism and Drug Delivery Device

Also Published As

Publication number Publication date
AR085523A1 (es) 2013-10-09
RU2013147640A (ru) 2015-04-27
TW201249495A (en) 2012-12-16
US9144649B2 (en) 2015-09-29
KR20140019813A (ko) 2014-02-17
AU2012234467A1 (en) 2013-10-10
IL228253B (en) 2018-04-30
CN103561801A (zh) 2014-02-05
NZ615854A (en) 2014-07-25
JP6150788B2 (ja) 2017-06-21
RU2606451C2 (ru) 2017-01-10
EP2688614A1 (en) 2014-01-29
JP2014513598A (ja) 2014-06-05
CA2830022A1 (en) 2012-10-04
EP2688614B1 (en) 2015-01-14
KR101961085B1 (ko) 2019-03-25
DK2688614T3 (en) 2015-04-20
CN103561801B (zh) 2015-08-05
MX336984B (es) 2016-02-09
AU2012234467B2 (en) 2015-11-26
MX2013010708A (es) 2013-10-01
SG193282A1 (en) 2013-10-30
BR112013023893B1 (pt) 2021-01-05
US20140018745A1 (en) 2014-01-16
TWI600446B (zh) 2017-10-01
MY164000A (en) 2017-11-15
ES2534081T3 (es) 2015-04-17
WO2012130703A1 (en) 2012-10-04
HK1189526A1 (en) 2014-06-13
ZA201306582B (en) 2014-05-28
PT2688614E (pt) 2015-04-15
CA2830022C (en) 2019-02-19

Similar Documents

Publication Publication Date Title
MX2020003112A (es) Composiciones de biguanida y metodos para tratar trastornos metabolicos.
BR112013025628A2 (pt) dispositivo de liberação de medicamento compreendendo um mecanismo de travamento com uma alavanca
BR112012011128A2 (pt) composição farmacêutica compreendendo um agonista de glp-1, uma insulina e uma metionina
BR112013023893A2 (pt) mecanismo de ajuste e dispositivo de injeção de dose
MY156679A (en) Pharmaceutical compositions
AR098738A1 (es) Análogos del péptido exendina-4 no acilados
BR112012027759A2 (pt) Conjugados de peptídeos de agonistas de receptores glp-1 e gastrina e seu uso
BR112015014658A2 (pt) dispositivo para liberação de medicamento
BR112015022623A2 (pt) composição e métodos baseados em anticorpos neutralizantes, administrados por via intranasal para eficácia terapêutica melhorada
CR20150200A (es) Derivados de exendina-4 como agonistas duales de glp1/glucacón
CU20130073A7 (es) Péptidos derivados del factor de crecimiento de fibroblastos 21 ( fgf21) útiles como reguladores metabólicos
BR112013024060A2 (pt) dispositivo de distribuição de fármacos com tampa protetora giratória
BR112015022972A2 (pt) composição farmacêutica de cloridrato de s-cetamina
EP4238597A3 (en) The invention relates to a drug delivery device
BR112015003109A2 (pt) Composto, composição, uso de um composto, e, métodos para tratar ou prevenir um distúrbio, condição ou doença e para tratar diabetes mellitus tipo 2.
BR112013019744A2 (pt) prevenção de hipoglicemia em pacientes com diabetes mellitus tipo 2
WO2008089268A3 (en) Methods and compositions for treating conditions associated with infection and/or inflammation
BRPI1002601E2 (pt) composição nanoestruturada de uso veterinário para administração de fármacos
BR112013024973A2 (pt) prevenção de hipoglicemia em pacientes com diabetes mellitus do tipo 2
BR112013021236A2 (pt) composto, composição,e, método de tratamento de um distúrbio, uma condição ou uma doença
BR112013020517A2 (pt) dispositivo de segurança
UY34359A (es) ?tratamiento de esclerosis múltiple con combinación de laquinimod e interferón-beta?.
MX2012006694A (es) Mecanismo de establecimiento de dosis.
BR112013029256A8 (pt) combinação farmacêutica para uso no tratamento de pacientes com diabetes tipo 2
BR112014004726A2 (pt) combinação farmacêutica para uso no controle glicêmico em pacientes de diabetes tipo 2

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/03/2012, OBSERVADAS AS CONDICOES LEGAIS.