BR112012030239A2 - composto ativo estabilizado - Google Patents

composto ativo estabilizado

Info

Publication number
BR112012030239A2
BR112012030239A2 BR112012030239A BR112012030239A BR112012030239A2 BR 112012030239 A2 BR112012030239 A2 BR 112012030239A2 BR 112012030239 A BR112012030239 A BR 112012030239A BR 112012030239 A BR112012030239 A BR 112012030239A BR 112012030239 A2 BR112012030239 A2 BR 112012030239A2
Authority
BR
Brazil
Prior art keywords
active compound
stabilized active
derivative
carrier
stabilized
Prior art date
Application number
BR112012030239A
Other languages
English (en)
Inventor
Audrey Leruite
Guy Broze
Khadija Tantaqui Eleraqi
Original Assignee
Prayon S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prayon S A filed Critical Prayon S A
Publication of BR112012030239A2 publication Critical patent/BR112012030239A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/26—Compounds containing phosphorus
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A23L33/155—Vitamins A or D
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

composto ativo estabilizado. a presente invenção diz respeito a compostos sólidos estáveis que compreendam um primeiro carreador e um adsorvato que compreenda, pelo menos, um componente ativo como, por exemplo, um derivado de vitamina d e um estabilizador hidrofóbico deste, e caracterizadas pelo fato de ser o aludido primeiro carreador um fosfato de cálcio, ou derivado deste dotados de uma solubilidade em água que seja inferior a 0,1% em peso, à temperatura ambiente.
BR112012030239A 2010-06-24 2011-06-24 composto ativo estabilizado BR112012030239A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2010059014 2010-06-24
PCT/EP2011/060618 WO2011161236A1 (en) 2010-06-24 2011-06-24 Stabilized active compound

Publications (1)

Publication Number Publication Date
BR112012030239A2 true BR112012030239A2 (pt) 2015-09-08

Family

ID=42537837

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012030239A BR112012030239A2 (pt) 2010-06-24 2011-06-24 composto ativo estabilizado

Country Status (11)

Country Link
US (1) US9757331B2 (pt)
JP (1) JP5817067B2 (pt)
CN (1) CN102958377A (pt)
BR (1) BR112012030239A2 (pt)
CA (1) CA2798019A1 (pt)
EA (1) EA022768B1 (pt)
ES (1) ES2725202T3 (pt)
MX (1) MX2012014872A (pt)
TR (1) TR201906042T4 (pt)
UA (1) UA107599C2 (pt)
WO (1) WO2011161236A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6171333B2 (ja) * 2012-12-26 2017-08-02 東ソー株式会社 安定化したビタミンｄ類標準液
WO2014158033A1 (en) 2013-03-27 2014-10-02 Psm Healthcare Limited Stabilized vitamin d formulations
US10336817B2 (en) 2016-10-14 2019-07-02 Sultan Qaboos University Therapeutic composition of camel milk
ES2882184T3 (es) * 2018-12-04 2021-12-01 Dsm Ip Assets Bv Adsorbatos estables al almacenamiento de nitrooxi-compuestos

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB405791A (en) 1933-01-14 1934-02-15 Bell And Sons Ltd Improvements in and relating to the manufacture of food accessories for cattle
US4389419A (en) 1980-11-10 1983-06-21 Damon Corporation Vitamin encapsulation
JPH085782B2 (ja) * 1989-04-14 1996-01-24 株式会社サンギ ハイドロキシアパタイト抗菌剤及びその製造法
DE19710054A1 (de) * 1997-03-12 1998-09-17 Merck Patent Gmbh Pharmazeutische Zubereitung
US5820903A (en) 1997-06-30 1998-10-13 General Mills, Inc. Calcium fortified yogurt and methods of preparation
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
JP2002080358A (ja) * 2000-09-07 2002-03-19 Noevir Co Ltd 皮膚外用剤
US6790462B2 (en) 2001-08-09 2004-09-14 Rhodia Inc. Calcium dietary supplement
US7632518B2 (en) 2002-01-15 2009-12-15 Dsm Ip Assets B.V. 25-hydroxy vitamin D3 compositions
DE10311585A1 (de) * 2003-03-14 2004-09-23 Basf Ag Wirkstoffhaltige Adsorbate
CA2669094A1 (en) * 2006-11-08 2008-05-29 Novavax,Inc. Method of preparing solid dosage forms of multi-phasic pharmaceutical compositions
US20100204204A1 (en) * 2007-06-06 2010-08-12 University Of South Florida Nutraceutical co-crystal compositions
EP2368440B1 (en) * 2007-06-29 2014-06-04 DSM IP Assets B.V. Feed additive composition comprising benzoic acid and a mixture of adsorbed essential oil compounds

Also Published As

Publication number Publication date
ES2725202T3 (es) 2019-09-20
UA107599C2 (xx) 2015-01-26
EA201270826A1 (ru) 2013-05-30
EA022768B1 (ru) 2016-02-29
US20130095150A1 (en) 2013-04-18
CA2798019A1 (en) 2011-12-29
MX2012014872A (es) 2013-01-24
JP5817067B2 (ja) 2015-11-18
US9757331B2 (en) 2017-09-12
CN102958377A (zh) 2013-03-06
JP2013532157A (ja) 2013-08-15
TR201906042T4 (tr) 2019-05-21
WO2011161236A1 (en) 2011-12-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 9/00 (2006.01), A23K 20/158 (2016.01), A23K 2