BR112012022603A2 - bactéria altamente produtiva produtora de álcool isopropyl - Google Patents

bactéria altamente produtiva produtora de álcool isopropyl

Info

Publication number
BR112012022603A2
BR112012022603A2 BR112012022603A BR112012022603A BR112012022603A2 BR 112012022603 A2 BR112012022603 A2 BR 112012022603A2 BR 112012022603 A BR112012022603 A BR 112012022603A BR 112012022603 A BR112012022603 A BR 112012022603A BR 112012022603 A2 BR112012022603 A2 BR 112012022603A2
Authority
BR
Brazil
Prior art keywords
isopropyl alcohol
highly productive
producing bacteria
escherichia coli
alcohol producing
Prior art date
Application number
BR112012022603A
Other languages
English (en)
Inventor
Hiroshi Shimizu
Hitoshi Takahashi
Junichiro Hirano
Koh Amano
Mitsufumi Wada
Nozomi Takebayashi
Takashi Hirasawa
Takashi Morishige
Tomokazu Shirai
Yoshiko Matsumoto
Original Assignee
Mitsui Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Chemicals Inc filed Critical Mitsui Chemicals Inc
Publication of BR112012022603A2 publication Critical patent/BR112012022603A2/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

bactéria altamente produtiva produtora de álcool isopropyl. um álcool isopropílico produtor de escherichia coli, equipada com um sistema de produção de álcool isopropílico, tendo pelo menos uma atividade enzimática melhorada selecionado do grupo consistindo em um aumento da atividade malato-desidrogenase, um reforço nad (p)^ +^ atividade transhydrogenase (ab-específica), e uma atividade de tiolase melhorada, e um álcool isopropílico produzindo método incluindo a produção de álcool isopropílico de matéria-prima derivada da planta, utilizando escherichia coli produtor de álcool isoporoílico de escherichia coli.
BR112012022603A 2010-03-09 2011-03-04 bactéria altamente produtiva produtora de álcool isopropyl BR112012022603A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010052249 2010-03-09
PCT/JP2011/055142 WO2011111638A1 (ja) 2010-03-09 2011-03-04 生産性の高いイソプロピルアルコール生産細菌

Publications (1)

Publication Number Publication Date
BR112012022603A2 true BR112012022603A2 (pt) 2015-11-03

Family

ID=44563441

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012022603A BR112012022603A2 (pt) 2010-03-09 2011-03-04 bactéria altamente produtiva produtora de álcool isopropyl

Country Status (10)

Country Link
US (1) US8932845B2 (pt)
EP (1) EP2546331B1 (pt)
JP (1) JP5628288B2 (pt)
CN (1) CN102791850B (pt)
BR (1) BR112012022603A2 (pt)
CA (1) CA2792546C (pt)
ES (1) ES2741637T3 (pt)
SG (1) SG183928A1 (pt)
TW (1) TWI500767B (pt)
WO (1) WO2011111638A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG2014009443A (en) * 2011-08-11 2014-08-28 Mitsui Chemicals Inc Method for producing isopropyl alcohol by continuous culture
WO2015152487A1 (ko) * 2014-04-03 2015-10-08 주식회사 퓨처플레이 사용자 인터페이스를 제공하기 위한 방법, 디바이스, 시스템 및 비일시성의 컴퓨터 판독 가능한 기록 매체
KR102621632B1 (ko) * 2014-05-12 2024-01-08 메타볼릭 익스플로러 Nadph 의존성 아세톨 리덕타제 및 개선된 nadph 공급에 기반한 1,2-프로판디올의 생산을 위한 신규한 미생물 및 방법
GB201519087D0 (en) * 2015-10-28 2015-12-09 Metabogen Ab Method for adaption

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1043956A (zh) * 1988-12-31 1990-07-18 孙书敏 用植物废料生产有机溶剂的工艺方法
DE10210960A1 (de) 2002-03-13 2003-09-25 Degussa Verfahren zur fermentativen Hestellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
DE102004038054A1 (de) * 2004-08-05 2006-03-16 Maxens Gmbh Verfahren zur Herstellung primärer Alkohole
US20080293125A1 (en) 2007-04-18 2008-11-27 Gevo, Inc. Engineered microorganisms for producing isopropanol
BRPI0814681B1 (pt) * 2007-07-11 2018-12-26 Mitsui Chemicals Inc bactéria produtora de álcool isopropílico recombinante do gênero escherichia e método de produzir álcool isopropílico usando a mesma
WO2009012210A2 (en) 2007-07-13 2009-01-22 Regents Of The University Of Minnesota Ethanol-producing microorganisms and methods of using
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
WO2009028582A1 (ja) * 2007-08-29 2009-03-05 Research Institute Of Innovative Technology For The Earth イソプロパノール生産能を有する形質転換体
CN101903530A (zh) 2007-10-12 2010-12-01 加利福尼亚大学董事会 被改造以产生异丙醇的微生物
EP2225373A4 (en) * 2007-12-13 2014-04-30 Glycos Biotechnologies Inc MICROBIAL CONVERSION OF OILS AND FATTY ACIDS IN HIGH-VALUE CHEMICALS
WO2009103026A1 (en) 2008-02-15 2009-08-20 Gevo, Inc. Engineered microorganisms for producing isopropanol
CA3081506A1 (en) 2008-03-05 2009-09-11 Genomatica, Inc. Long chain alcohol-producing organisms
JP2009247217A (ja) 2008-04-01 2009-10-29 Kyushu Univ 好気性組み換え微生物を用いる2−プロパノールの製造方法
JP5407222B2 (ja) 2008-08-28 2014-02-05 東洋紡株式会社 レーザー彫刻用凸版印刷原版及びそれから得られる凸版印刷版
CN107586753A (zh) * 2009-09-09 2018-01-16 基因组股份公司 协同产生异丙醇与伯醇,二元醇和酸的微生物和方法

Also Published As

Publication number Publication date
CA2792546A1 (en) 2011-09-15
CA2792546C (en) 2015-11-24
JPWO2011111638A1 (ja) 2013-06-27
CN102791850A (zh) 2012-11-21
JP5628288B2 (ja) 2014-11-19
ES2741637T3 (es) 2020-02-11
EP2546331B1 (en) 2019-07-03
US8932845B2 (en) 2015-01-13
SG183928A1 (en) 2012-10-30
TWI500767B (zh) 2015-09-21
WO2011111638A1 (ja) 2011-09-15
TW201202428A (en) 2012-01-16
EP2546331A1 (en) 2013-01-16
EP2546331A4 (en) 2013-10-23
US20130005008A1 (en) 2013-01-03
CN102791850B (zh) 2018-01-09

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Legal Events

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B08F Application fees: application dismissed [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B08H Application fees: decision cancelled [chapter 8.8 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal: appeal against refusal