BR112012022052B1 - Uso de dextrometorfano ou dextorfano e uso de dextrometorfano e dextrofano e gabapentina - Google Patents

Uso de dextrometorfano ou dextorfano e uso de dextrometorfano e dextrofano e gabapentina Download PDF

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Publication number
BR112012022052B1
BR112012022052B1 BR112012022052-7A BR112012022052A BR112012022052B1 BR 112012022052 B1 BR112012022052 B1 BR 112012022052B1 BR 112012022052 A BR112012022052 A BR 112012022052A BR 112012022052 B1 BR112012022052 B1 BR 112012022052B1
Authority
BR
Brazil
Prior art keywords
symptoms
dextromethorphan
hot flashes
hormonal
sub
Prior art date
Application number
BR112012022052-7A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112012022052A2 (pt
Inventor
George E. Royster Jr.
Original Assignee
Fervent Pharmaceuticals, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fervent Pharmaceuticals, Llc filed Critical Fervent Pharmaceuticals, Llc
Publication of BR112012022052A2 publication Critical patent/BR112012022052A2/pt
Publication of BR112012022052B1 publication Critical patent/BR112012022052B1/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112012022052-7A 2010-03-02 2011-03-01 Uso de dextrometorfano ou dextorfano e uso de dextrometorfano e dextrofano e gabapentina BR112012022052B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30963810P 2010-03-02 2010-03-02
US61/309,638 2010-03-02
PCT/US2011/026650 WO2011109367A2 (en) 2010-03-02 2011-03-01 Methods and compositions for treating or preventing symptoms of hormonal variations

Publications (2)

Publication Number Publication Date
BR112012022052A2 BR112012022052A2 (pt) 2020-07-07
BR112012022052B1 true BR112012022052B1 (pt) 2021-06-29

Family

ID=44531862

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012022052-7A BR112012022052B1 (pt) 2010-03-02 2011-03-01 Uso de dextrometorfano ou dextorfano e uso de dextrometorfano e dextrofano e gabapentina

Country Status (12)

Country Link
US (1) US20110218213A1 (https=)
EP (1) EP2542241B1 (https=)
JP (1) JP5839362B2 (https=)
CN (1) CN102858343B (https=)
AU (3) AU2011223807B2 (https=)
BR (1) BR112012022052B1 (https=)
CA (1) CA2828041C (https=)
EA (1) EA027350B1 (https=)
ES (1) ES2574210T3 (https=)
IL (2) IL221706A (https=)
PL (1) PL2542241T3 (https=)
WO (1) WO2011109367A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9616123B1 (en) * 2012-03-05 2017-04-11 Robert L. Knobler Method and compound for treatment of menopausal symptoms
SG11201708162UA (en) * 2015-04-07 2017-11-29 Meiji Co Ltd Hot flash-suppressing agent
WO2019094757A1 (en) 2017-11-09 2019-05-16 The Trustees Of Columbia University In The City Of New York Pharmacological prophylactics against stress-induced affective disorders in females
US11622948B2 (en) 2017-11-09 2023-04-11 The Trustees Of Columbia University In The City Of New York Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders
CA3137710A1 (en) * 2019-04-22 2020-10-29 Robert L. Knobler Non-hormonal treatment of hot flashes
US20220401366A1 (en) * 2019-11-15 2022-12-22 Consegna Pharma, Inc. Long acting nmda antagonists

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
CA2115792C (en) * 1993-03-05 2005-11-01 David J. Mayer Method for the treatment of pain
EP2283821A1 (en) * 1993-11-19 2011-02-16 Alkermes, Inc. Preparation of biodegradable microparticles containing a biologically active agent
AUPN605795A0 (en) * 1995-10-19 1995-11-09 F.H. Faulding & Co. Limited Analgesic pharmaceutical composition
ES2287021T3 (es) * 1999-07-22 2007-12-16 University Of Rochester Metodo para el tratamiento de sintomas de variacines hormonales que incluyen el fogaje.
US20040002482A1 (en) * 2000-08-30 2004-01-01 Dudley Robert E. Androgen pharmaceutical composition and method for treating depression
US6569471B2 (en) * 2000-09-01 2003-05-27 Natumin Pharma Ab Method for the treatment of symptoms related to normal hormonal variations in women
US20050129783A1 (en) * 2001-04-19 2005-06-16 Mccleary Edward L. Composition and method for treatment of neurophysiological conditions and maintenance of neurophysiological health
WO2003037334A1 (en) * 2001-10-31 2003-05-08 Merck & Co., Inc. Method for treating or preventing symptoms of hormonal variation including hot flashes
JP2006500366A (ja) * 2002-08-15 2006-01-05 ワイス 温度調節機能障害の治療ための5HT2a受容体の拮抗
HUP0303313A2 (hu) * 2003-10-09 2005-07-28 Richter Gedeon Vegyészeti Gyár Rt. Transzdermális gyógyszerkészítmények
US7855195B2 (en) * 2003-12-02 2010-12-21 Pharmaneuroboost N.V. Method of treating mental disorders using D4 and 5-HT2A antagonists, inverse agonists or partial agonists
MXPA06013163A (es) * 2004-05-11 2007-02-13 Pfizer Prod Inc Combinacion de antipsicoticos atipicos y antagonistas del receptor 5-ht1b.
CA2569411A1 (en) * 2004-06-04 2005-12-22 Mood Management Sciences, Llc Methods and compositions for treating mood disorder
EP1827450A4 (en) * 2004-11-17 2009-04-22 Cypress Bioscience Inc METHOD FOR REDUCING THE SIDE EFFECTS OF TREATMENT WITH MIRTAZAPINE
JP2009500421A (ja) * 2005-07-06 2009-01-08 セプラコア インコーポレーテッド エスゾピクロン及び抗うつ薬の組み合わせ
WO2007070779A2 (en) * 2005-12-13 2007-06-21 Trinity Laboratories, Inc. A method to treat premature ejaculation in humans
EP1986639A4 (en) * 2006-02-03 2010-04-28 Avanir Pharmaceuticals PHARMACEUTICAL COMPOSITIONS OF DEXTROMETHORPHANE AND CHINIDINE FOR THE TREATMENT OF DEPRESSION, FEAR STATES AND NEURODEEGENERATIVE DISEASES
US7645750B2 (en) * 2006-12-13 2010-01-12 Yung Shin Pharmaceutical Ind. Co., Ltd. Method of treating symptoms of hormonal variations
HRP20130713T1 (en) * 2007-03-19 2013-09-30 Acadia Pharmaceuticals Inc. Combinations of 5-ht2a inverse agonists and antagonists with antipsychotics
EP2323688B1 (en) * 2008-07-22 2018-10-17 MenoGeniX, Inc. Compositions and methods for treating symptoms associated with menopause, hormonal variations and arthritis

Also Published As

Publication number Publication date
AU2016213776A1 (en) 2016-09-01
US20110218213A1 (en) 2011-09-08
CA2828041A1 (en) 2011-09-09
BR112012022052A2 (pt) 2020-07-07
JP2013521297A (ja) 2013-06-10
JP5839362B2 (ja) 2016-01-06
AU2011223807A1 (en) 2012-10-18
CA2828041C (en) 2018-04-17
EA027350B1 (ru) 2017-07-31
AU2011223807B2 (en) 2016-05-12
PL2542241T3 (pl) 2016-12-30
AU2018205147A1 (en) 2018-08-02
WO2011109367A3 (en) 2011-12-29
EP2542241A4 (en) 2013-11-06
CN102858343B (zh) 2015-11-25
CN102858343A (zh) 2013-01-02
IL221706A (en) 2017-08-31
AU2016213776B2 (en) 2018-04-12
WO2011109367A4 (en) 2012-02-23
ES2574210T3 (es) 2016-06-15
IL253853B (en) 2019-05-30
IL253853A0 (en) 2017-09-28
EA201290851A1 (ru) 2013-04-30
EP2542241A2 (en) 2013-01-09
EP2542241B1 (en) 2016-04-27
WO2011109367A2 (en) 2011-09-09

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 01/03/2011, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, , QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.