BR112012014316A2 - poliuretano-uréia para revestimentos de stent - Google Patents

poliuretano-uréia para revestimentos de stent

Info

Publication number
BR112012014316A2
BR112012014316A2 BR112012014316A BR112012014316A BR112012014316A2 BR 112012014316 A2 BR112012014316 A2 BR 112012014316A2 BR 112012014316 A BR112012014316 A BR 112012014316A BR 112012014316 A BR112012014316 A BR 112012014316A BR 112012014316 A2 BR112012014316 A2 BR 112012014316A2
Authority
BR
Brazil
Prior art keywords
polyurethane urea
stent coatings
substrate
urea according
layer
Prior art date
Application number
BR112012014316A
Other languages
English (en)
Inventor
Christian Wamprecht
Henning Rohm
Jürgen Köcher
Katrin Sternberg
Klaus-Peter Schmitz
Original Assignee
Bayer Materialscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Materialscience Ag filed Critical Bayer Materialscience Ag
Publication of BR112012014316A2 publication Critical patent/BR112012014316A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/42Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/44Polycarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/0804Manufacture of polymers containing ionic or ionogenic groups
    • C08G18/0819Manufacture of polymers containing ionic or ionogenic groups containing anionic or anionogenic groups
    • C08G18/0823Manufacture of polymers containing ionic or ionogenic groups containing anionic or anionogenic groups containing carboxylate salt groups or groups forming them
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/10Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C08G18/12Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step using two or more compounds having active hydrogen in the first polymerisation step
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D175/00Coating compositions based on polyureas or polyurethanes; Coating compositions based on derivatives of such polymers
    • C09D175/04Polyurethanes
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D175/00Coating compositions based on polyureas or polyurethanes; Coating compositions based on derivatives of such polymers
    • C09D175/04Polyurethanes
    • C09D175/06Polyurethanes from polyesters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Manufacturing & Machinery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Materials For Medical Uses (AREA)
  • Paints Or Removers (AREA)
  • Laminated Bodies (AREA)

Abstract

poliuretano-uréia para revestimentos de stent. a invenção se refere a uma poliuretano-uréia, que apresenta unidades estruturais da fórmula (i), não terminada com pelo menos uma unidade copolimérica de óxido de polietileno e óxido de polipropileno e que pode ser particularmente usada para a produção de revestimentos de stents. um outro objetivo da invenção é um substrato com um revestimento básico de uma poliuretano-uréia de acordo com a invenção. do mesmo modo, é objetivo da invenção uma estrtutura de camadas compreendendo pelo menos uma camada contendo substância ativa de uma poliuretano-uréia de acordo com a invenção. finalmente, um processo revestir um sustrato, no qual sobre o substrato é aplicada pelo menos uma camada de uma poliuretano-uréia de acordo com a invenção também é objetivo da invenção.
BR112012014316A 2009-12-16 2010-12-10 poliuretano-uréia para revestimentos de stent BR112012014316A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09015532 2009-12-16
PCT/EP2010/069393 WO2011082946A1 (de) 2009-12-16 2010-12-10 Polyurethanharnstoff für stentbeschichtungen

Publications (1)

Publication Number Publication Date
BR112012014316A2 true BR112012014316A2 (pt) 2016-07-05

Family

ID=42115595

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012014316A BR112012014316A2 (pt) 2009-12-16 2010-12-10 poliuretano-uréia para revestimentos de stent

Country Status (10)

Country Link
US (1) US20120263778A1 (pt)
EP (1) EP2513177B1 (pt)
JP (1) JP2013514395A (pt)
KR (1) KR20120103639A (pt)
CN (1) CN102947361B (pt)
AU (1) AU2010340995A1 (pt)
BR (1) BR112012014316A2 (pt)
CA (1) CA2784217A1 (pt)
ES (1) ES2527621T3 (pt)
WO (1) WO2011082946A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010025840A1 (de) * 2008-09-04 2010-03-11 Bayer Materialscience Ag Tcd-basierte hydrophile polyurethandispersionen
WO2013079476A1 (de) 2011-11-30 2013-06-06 Bayer Materialscience Ag Arzneimittelbeschichtetes medizinisches gerät und verfahren zu dessen herstellung
WO2013083511A1 (de) 2011-12-06 2013-06-13 Bayer Intellectual Property Gmbh Tcd-alkohol-basierende thermoplastische polyurethanharnstoff-polymere und deren verwendung
CN102692184B (zh) * 2012-02-29 2014-07-23 首钢总公司 一种同时测量腐蚀坑体积、面积、深度的方法
WO2015035387A1 (en) * 2013-09-09 2015-03-12 Arsenal Medical, Inc. Drug delivery systems and related methods
WO2015081904A2 (en) * 2015-01-19 2015-06-11 Bayer Materialscience Ag Polyurethaneurea solutions for compositions with active ingredients or fragrances
CN112638436A (zh) * 2018-05-22 2021-04-09 界面生物公司 用于将药物递送至血管壁的组合物和方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589563A (en) * 1992-04-24 1996-12-31 The Polymer Technology Group Surface-modifying endgroups for biomedical polymers
AU729736B2 (en) * 1997-11-07 2001-02-08 Salviac Limited Biostable polycarbonate urethane products
JP2002243995A (ja) * 2001-02-13 2002-08-28 Shin Etsu Chem Co Ltd 光ファイバ心線
DE10152294A1 (de) * 2001-10-26 2003-05-08 Solutia Austria Gmbh Werndorf Hochmolekulare Polyurethan-Dispersionen
US20050043585A1 (en) * 2003-01-03 2005-02-24 Arindam Datta Reticulated elastomeric matrices, their manufacture and use in implantable devices
DE102005010998A1 (de) 2004-12-08 2006-06-29 Bayer Innovation Gmbh Wirkstoff abgebende Stents
TW200643059A (en) * 2005-04-06 2006-12-16 Showa Denko Kk Polymer of polycarbonate diol having an alicyclic structure and production process thereof
WO2009012391A1 (en) * 2007-07-17 2009-01-22 Sabic Innovative Plastics Ip B.V. Aliphatic polycarbonates for use in thermosetting powder coatings
EP2103638A1 (de) 2008-03-20 2009-09-23 Bayer MaterialScience AG Hydrophile Polyurethanlösungen

Also Published As

Publication number Publication date
US20120263778A1 (en) 2012-10-18
WO2011082946A1 (de) 2011-07-14
CN102947361A (zh) 2013-02-27
JP2013514395A (ja) 2013-04-25
AU2010340995A1 (en) 2012-07-05
KR20120103639A (ko) 2012-09-19
EP2513177A1 (de) 2012-10-24
CA2784217A1 (en) 2011-07-14
ES2527621T3 (es) 2015-01-27
CN102947361B (zh) 2015-04-01
EP2513177B1 (de) 2014-12-10

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A E 5A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]