BR112012010108A2 - métodos para auxiliar no diagnóstico e para monitorar a progressão ou regressão da síndrome do intestino irritável, meio legível por computador, e, sistema para classificar se uma amostra de soro ou sangue de um indivíduo está associada com a síndrome do intestino irritável - Google Patents
métodos para auxiliar no diagnóstico e para monitorar a progressão ou regressão da síndrome do intestino irritável, meio legível por computador, e, sistema para classificar se uma amostra de soro ou sangue de um indivíduo está associada com a síndrome do intestino irritávelInfo
- Publication number
- BR112012010108A2 BR112012010108A2 BR112012010108A BR112012010108A BR112012010108A2 BR 112012010108 A2 BR112012010108 A2 BR 112012010108A2 BR 112012010108 A BR112012010108 A BR 112012010108A BR 112012010108 A BR112012010108 A BR 112012010108A BR 112012010108 A2 BR112012010108 A2 BR 112012010108A2
- Authority
- BR
- Brazil
- Prior art keywords
- bowel syndrome
- irritable bowel
- methods
- serum
- regression
- Prior art date
Links
- 208000002551 irritable bowel syndrome Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 238000003745 diagnosis Methods 0.000 title abstract 3
- 210000002966 serum Anatomy 0.000 title abstract 3
- 210000004369 blood Anatomy 0.000 title abstract 2
- 239000008280 blood Substances 0.000 title abstract 2
- 238000012544 monitoring process Methods 0.000 title abstract 2
- 239000000090 biomarker Substances 0.000 abstract 1
- 239000000101 novel biomarker Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25671709P | 2009-10-30 | 2009-10-30 | |
| US26458809P | 2009-11-25 | 2009-11-25 | |
| US32617610P | 2010-04-20 | 2010-04-20 | |
| PCT/US2010/054810 WO2011053831A1 (en) | 2009-10-30 | 2010-10-29 | Methods for diagnosing irritable bowel syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012010108A2 true BR112012010108A2 (pt) | 2016-05-31 |
Family
ID=43922588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012010108A BR112012010108A2 (pt) | 2009-10-30 | 2010-10-29 | métodos para auxiliar no diagnóstico e para monitorar a progressão ou regressão da síndrome do intestino irritável, meio legível por computador, e, sistema para classificar se uma amostra de soro ou sangue de um indivíduo está associada com a síndrome do intestino irritável |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20120315630A1 (enExample) |
| EP (1) | EP2494074A4 (enExample) |
| JP (1) | JP2013509593A (enExample) |
| KR (1) | KR20120101038A (enExample) |
| CN (1) | CN102712956A (enExample) |
| AU (1) | AU2010313292A1 (enExample) |
| BR (1) | BR112012010108A2 (enExample) |
| CA (1) | CA2778539A1 (enExample) |
| IL (1) | IL219317A0 (enExample) |
| MX (1) | MX2012005015A (enExample) |
| PH (1) | PH12012500850A1 (enExample) |
| RU (1) | RU2012122180A (enExample) |
| WO (1) | WO2011053831A1 (enExample) |
| ZA (1) | ZA201203718B (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5857503B2 (ja) * | 2010-07-29 | 2016-02-10 | 小野薬品工業株式会社 | ストレス性疾患のバイオマーカー |
| WO2012158831A1 (en) | 2011-05-16 | 2012-11-22 | Prometheus Laboratories Inc. | Performance of a biomarker panel for irritable bowel syndrome |
| NZ702643A (en) * | 2012-05-19 | 2016-06-24 | Falk Pharma Gmbh | Compositions and methods for treatment of irritable bowel syndrome with 5-aminosalicylate |
| AU2013326133B2 (en) * | 2012-10-05 | 2019-07-04 | Société des Produits Nestlé S.A. | Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for IBS |
| WO2014082034A1 (en) * | 2012-11-26 | 2014-05-30 | Lexicon Pharmaceuticals, Inc. | Methods for treating irritable bowel syndrome |
| CN103175971B (zh) * | 2013-02-28 | 2016-10-05 | 苏州和锐医药科技有限公司 | 一种IgA抗体检测试剂盒 |
| EP3800470A1 (en) * | 2013-03-15 | 2021-04-07 | Sera Prognostics, Inc. | Biomarkers and methods for predicting preterm birth |
| GB201305708D0 (en) * | 2013-03-28 | 2013-05-15 | Clasado Inc | Novel use |
| RU2015155552A (ru) * | 2013-05-24 | 2017-06-27 | Нестек С.А. | Путеспецифические способы прогнозирования диагноза синдрома раздраженного кишечника |
| CA2930330A1 (en) * | 2013-12-27 | 2015-07-02 | Dignity Health | Diagnosing and treating alzheimer's disease |
| JP6713723B2 (ja) * | 2014-02-18 | 2020-06-24 | 小野薬品工業株式会社 | 過敏性腸症候群の診断用バイオマーカー |
| US10392665B2 (en) | 2015-06-19 | 2019-08-27 | Sera Prognostics, Inc. | Biomarker pairs for predicting preterm birth |
| CN106446599A (zh) * | 2015-08-11 | 2017-02-22 | 中国科学院青岛生物能源与过程研究所 | 一种筛选婴幼儿龋病的口腔致病性生物标记物的方法 |
| CN105687225B (zh) * | 2016-02-26 | 2018-07-06 | 四川好医生攀西药业有限责任公司 | 一种治疗肠易激综合征的药物组合物及其制备方法和应用 |
| GB201605110D0 (en) * | 2016-03-24 | 2016-05-11 | Mologic Ltd | Detecting sepsis |
| US10817778B2 (en) | 2016-06-27 | 2020-10-27 | International Business Machines Corporation | Customized cooking utilizing deep learning neuromorphic computing of hyperspectral input |
| AU2017325986B2 (en) * | 2016-09-16 | 2023-12-14 | Takeda Pharmaceutical Company Limited | Metabolite biomarkers for diseases associated with the contact activation system |
| RU2668496C2 (ru) * | 2017-03-16 | 2018-10-01 | Государственное бюджетное учреждение здравоохранения города Москвы Московский клинический научно-практический центр Департамента здравоохранения города Москвы | Способ диагностики тяжести течения синдрома раздраженного кишечника |
| CN106990057A (zh) * | 2017-05-05 | 2017-07-28 | 贵州普洛迈德生物工程有限公司 | 一种检测5‑羟吲哚乙酸试剂及制备方法 |
| US11662351B2 (en) | 2017-08-18 | 2023-05-30 | Sera Prognostics, Inc. | Pregnancy clock proteins for predicting due date and time to birth |
| US11488699B1 (en) | 2018-12-09 | 2022-11-01 | Cerner Innovation, Inc. | Microbiota activity sensor and decision support tool |
| US11842795B1 (en) * | 2018-12-17 | 2023-12-12 | Cerner Innovation, Inc. | Irritable bowel syndrome diagnostic sensor and decision support tool |
| KR102330639B1 (ko) * | 2019-01-18 | 2021-11-24 | 주식회사 천랩 | 과민성대장증후군 특이적 미생물 바이오마커와 이를 이용하여 과민성대장증후군의 위험도를 예측하는 방법 |
| US20220146527A1 (en) * | 2019-09-17 | 2022-05-12 | Chang Gung University | Method of creating characteristic profiles of mass spectra and identification model for analyzing and identifying features of microorganisms |
| US20240124524A1 (en) * | 2019-10-17 | 2024-04-18 | University Of Copenhagen | Agonist of Tacr2 |
| CN112921100A (zh) * | 2019-12-06 | 2021-06-08 | 宁波海尔施基因科技有限公司 | 一种检测人类压力敏感度基因型的试剂盒和方法 |
| EP3913371A1 (en) * | 2020-05-18 | 2021-11-24 | Neuroimmun GmbH | Method and kit for diagnosting irritable bowel syndrome and for its relief through dietary interventions |
| CN111784683B (zh) * | 2020-07-10 | 2022-05-17 | 天津大学 | 病理切片检测方法及装置、计算机设备及存储介质 |
| CN111905111B (zh) * | 2020-09-16 | 2023-03-31 | 地奥集团成都药业股份有限公司 | 一种评价复方谷氨酰胺组方对腹泻型肠易激综合征疗效的方法 |
| US20220208375A1 (en) * | 2020-12-29 | 2022-06-30 | Kpn Innovations, Llc. | System and method for generating a digestive disease functional program |
| CN115328117B (zh) * | 2022-07-15 | 2023-07-14 | 大理大学 | 基于强化学习的蛋白质动态配体通道最优路径分析方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999057120A1 (en) * | 1998-05-04 | 1999-11-11 | Neotherapeutics, Inc. | Novel serotonin-like 9-substituted hypoxanthine and methods of use |
| EP1315837A2 (en) * | 2000-09-06 | 2003-06-04 | Glaxo Group Limited | 5-hydroxytryptamine receptor gene polymorphisms and response to treatment |
| US20080085524A1 (en) * | 2006-08-15 | 2008-04-10 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
| EP2778685B1 (en) * | 2009-06-25 | 2017-04-26 | Nestec S.A. | Methods for diagnosing irritable bowel syndrome |
-
2010
- 2010-10-29 EP EP10827556.1A patent/EP2494074A4/en not_active Withdrawn
- 2010-10-29 CA CA2778539A patent/CA2778539A1/en not_active Abandoned
- 2010-10-29 JP JP2012537132A patent/JP2013509593A/ja not_active Withdrawn
- 2010-10-29 MX MX2012005015A patent/MX2012005015A/es unknown
- 2010-10-29 CN CN2010800605536A patent/CN102712956A/zh active Pending
- 2010-10-29 WO PCT/US2010/054810 patent/WO2011053831A1/en not_active Ceased
- 2010-10-29 RU RU2012122180/15A patent/RU2012122180A/ru unknown
- 2010-10-29 PH PH1/2012/500850A patent/PH12012500850A1/en unknown
- 2010-10-29 KR KR1020127013948A patent/KR20120101038A/ko not_active Withdrawn
- 2010-10-29 BR BR112012010108A patent/BR112012010108A2/pt not_active IP Right Cessation
- 2010-10-29 AU AU2010313292A patent/AU2010313292A1/en not_active Abandoned
-
2012
- 2012-04-06 US US13/441,658 patent/US20120315630A1/en not_active Abandoned
- 2012-04-19 IL IL219317A patent/IL219317A0/en unknown
- 2012-05-22 ZA ZA2012/03718A patent/ZA201203718B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20120315630A1 (en) | 2012-12-13 |
| ZA201203718B (en) | 2014-11-26 |
| RU2012122180A (ru) | 2013-12-10 |
| MX2012005015A (es) | 2012-06-12 |
| IL219317A0 (en) | 2012-06-28 |
| PH12012500850A1 (en) | 2013-01-07 |
| CN102712956A (zh) | 2012-10-03 |
| JP2013509593A (ja) | 2013-03-14 |
| CA2778539A1 (en) | 2011-05-05 |
| AU2010313292A1 (en) | 2012-06-07 |
| EP2494074A4 (en) | 2013-06-12 |
| KR20120101038A (ko) | 2012-09-12 |
| WO2011053831A1 (en) | 2011-05-05 |
| EP2494074A1 (en) | 2012-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A E 6A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
|
| B25B | Requested transfer of rights rejected |
Owner name: PROMETHEUS LABORATOIRES INC. (US) |