BR112012000490A2 - uso da combinação de teriflunomida e interferon beta para o tratamento da esclerose múltipla - Google Patents

uso da combinação de teriflunomida e interferon beta para o tratamento da esclerose múltipla

Info

Publication number
BR112012000490A2
BR112012000490A2 BR112012000490A BR112012000490A BR112012000490A2 BR 112012000490 A2 BR112012000490 A2 BR 112012000490A2 BR 112012000490 A BR112012000490 A BR 112012000490A BR 112012000490 A BR112012000490 A BR 112012000490A BR 112012000490 A2 BR112012000490 A2 BR 112012000490A2
Authority
BR
Brazil
Prior art keywords
teriflunomide
treatment
combination
multiple sclerosis
interferon beta
Prior art date
Application number
BR112012000490A
Other languages
English (en)
Inventor
Gerald Frangin
Patrice Douillet
William Byrnes
Original Assignee
Sanofi Aventis Us Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41283539&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012000490(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Us Llc filed Critical Sanofi Aventis Us Llc
Publication of BR112012000490A2 publication Critical patent/BR112012000490A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR112012000490A 2009-07-10 2010-07-08 uso da combinação de teriflunomida e interferon beta para o tratamento da esclerose múltipla BR112012000490A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09305669A EP2277515A1 (en) 2009-07-10 2009-07-10 Use of the combination of teriflunomide and interferon beta for treating multiple sclerosis
US22534209P 2009-07-14 2009-07-14
US28614809P 2009-12-14 2009-12-14
US35095710P 2010-06-03 2010-06-03
PCT/US2010/041274 WO2011005907A1 (en) 2009-07-10 2010-07-08 Use of the combination of teriflunomide and interferon beta for treating multiple sclerosis

Publications (1)

Publication Number Publication Date
BR112012000490A2 true BR112012000490A2 (pt) 2016-02-16

Family

ID=41283539

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012000490A BR112012000490A2 (pt) 2009-07-10 2010-07-08 uso da combinação de teriflunomida e interferon beta para o tratamento da esclerose múltipla

Country Status (20)

Country Link
US (2) US20120107277A1 (pt)
EP (2) EP2277515A1 (pt)
JP (1) JP2012532881A (pt)
KR (1) KR20120050976A (pt)
CN (1) CN102470116A (pt)
AR (1) AR077460A1 (pt)
AU (1) AU2010271467A1 (pt)
BR (1) BR112012000490A2 (pt)
CA (1) CA2767711A1 (pt)
CL (1) CL2012000062A1 (pt)
CO (1) CO6491023A2 (pt)
IL (1) IL217434A0 (pt)
MA (1) MA33515B1 (pt)
MX (1) MX2012000458A (pt)
RU (1) RU2012104666A (pt)
SG (1) SG177544A1 (pt)
TW (1) TW201106945A (pt)
UY (1) UY32781A (pt)
WO (1) WO2011005907A1 (pt)
ZA (1) ZA201108340B (pt)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0123571D0 (en) 2001-04-05 2001-11-21 Aventis Pharm Prod Inc Use of (Z)-2-cyano-3-hydroxy-but-2-enoic acid-(4'-trifluoromethylphenyl)-amide for treating multiple sclerosis
EP1935416A3 (en) * 2001-04-05 2008-10-22 Aventis Pharma Inc (Z) -2-cyano-3-hydroxybut-2-enoic acid (4'-trifluoromethylphenyl) amide for the treatment of multiple sclerosis
CN101043883A (zh) * 2004-10-19 2007-09-26 安万特药物公司 (z)－2－氰基－3－羟基－丁－2－烯酸－(4'－三氟甲基苯基)－酰胺用于治疗炎症性肠病的用途

Also Published As

Publication number Publication date
SG177544A1 (en) 2012-03-29
UY32781A (es) 2011-02-28
CA2767711A1 (en) 2011-01-13
CO6491023A2 (es) 2012-07-31
AU2010271467A1 (en) 2012-02-02
IL217434A0 (en) 2012-02-29
TW201106945A (en) 2011-03-01
AR077460A1 (es) 2011-08-31
JP2012532881A (ja) 2012-12-20
WO2011005907A1 (en) 2011-01-13
EP2451449A1 (en) 2012-05-16
EP2451449B1 (en) 2014-05-07
EP2277515A1 (en) 2011-01-26
KR20120050976A (ko) 2012-05-21
CL2012000062A1 (es) 2012-10-05
ZA201108340B (en) 2012-07-25
RU2012104666A (ru) 2013-08-20
MX2012000458A (es) 2012-01-27
CN102470116A (zh) 2012-05-23
US20130156735A1 (en) 2013-06-20
US20120107277A1 (en) 2012-05-03
MA33515B1 (fr) 2012-08-01

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]