BR0315206A - Compostos antimicrobianos de 1-aril-diidropiridona - Google Patents

Compostos antimicrobianos de 1-aril-diidropiridona

Info

Publication number
BR0315206A
BR0315206A BR0315206-5A BR0315206A BR0315206A BR 0315206 A BR0315206 A BR 0315206A BR 0315206 A BR0315206 A BR 0315206A BR 0315206 A BR0315206 A BR 0315206A
Authority
BR
Brazil
Prior art keywords
aryl
dihydropyridone
het
antimicrobial compounds
nhc
Prior art date
Application number
BR0315206-5A
Other languages
English (en)
Inventor
Mikhail Fedor Gordeev
Upinder Singh
Dinesh Vinoobhai Patel
Paul Dennis May
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BR0315206A publication Critical patent/BR0315206A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"COMPOSTOS ANTIMICROBIANOS DE 1-ARIL-DIIDROPIRIDONA". A presente invenção fornece agentes antibacterianos da fórmula (I), ou um seu sal farmaceuticamente aceitável, onde A é uma estrutura (i), (ii), (iii), ou (iv); X é (a) NHC(=O)R^ 1^, (b) NHC(=S)R^ 1^, (c) NH-het^ 1^, (d) O-Het^ 1^, (e) S-het^ 1^, ou (f) het^ 2^.
BR0315206-5A 2002-10-10 2003-10-03 Compostos antimicrobianos de 1-aril-diidropiridona BR0315206A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41749202P 2002-10-10 2002-10-10
PCT/IB2003/004380 WO2004033449A1 (en) 2002-10-10 2003-10-03 Antimicrobial 1-aryl dihydropyridone compounds

Publications (1)

Publication Number Publication Date
BR0315206A true BR0315206A (pt) 2005-08-16

Family

ID=32094028

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0315206-5A BR0315206A (pt) 2002-10-10 2003-10-03 Compostos antimicrobianos de 1-aril-diidropiridona

Country Status (10)

Country Link
US (1) US7105547B2 (pt)
EP (1) EP1554273A1 (pt)
JP (1) JP2006504726A (pt)
AR (1) AR041556A1 (pt)
AU (1) AU2003265090A1 (pt)
BR (1) BR0315206A (pt)
CA (1) CA2499105A1 (pt)
MX (1) MXPA05003774A (pt)
TW (1) TW200420561A (pt)
WO (1) WO2004033449A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208490B2 (en) 2002-10-07 2007-04-24 Pharmacia & Upjohn Company Llc Tricyclic tetrahydroquinoline antibacterial agents
CN101720325B (zh) * 2007-08-06 2013-04-24 上海盟科药业有限公司 用于治疗细菌感染的抗菌邻-氟苯基噁唑烷酮
CN101798302B (zh) 2009-02-06 2014-11-05 上海盟科药业有限公司 抗生素类药物1-(邻-氟苯基)二氢吡啶酮的合成及生产的方法和工艺
CN102206213A (zh) * 2010-03-31 2011-10-05 盟科医药技术(上海)有限公司 (5s)-5-[(异噁唑-3-基氨基)甲基]-3-[2,3,5-三氟-4-(4-氧代-2,3-二氢吡啶-1-基)苯基]噁唑烷-2-酮的药物晶型
WO2015127316A1 (en) 2014-02-21 2015-08-27 Micurx Pharmaceuticals, Inc. Water-soluble o-carbonyl phosphoramidate prodrugs for therapeutic administration
CN108727406B (zh) * 2017-03-28 2021-12-07 北京协和制药二厂 含氮杂环取代的苯并噁嗪噁唑烷酮类化合物及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283420B6 (sk) 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5668286A (en) 1994-03-15 1997-09-16 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them
ATE293609T1 (de) * 1997-05-30 2005-05-15 Upjohn Co Antibakteriell wirksam oxazolidinone mit einer thiocarbonylfunktionalität
ATE222894T1 (de) 1998-02-13 2002-09-15 Upjohn Co Substituierte aminophenylisoxazolinderivate verwendbar als antimikrobielle agenzien
TW572757B (en) * 1998-08-24 2004-01-21 Bristol Myers Squibb Co Novel isoxazolinone antibacterial agents
EP1472247A1 (en) * 2002-02-05 2004-11-03 PHARMACIA & UPJOHN COMPANY Antimicrobial thiadiazinone derivatives useful in treatment of bacterial infections
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados

Also Published As

Publication number Publication date
AU2003265090A1 (en) 2004-05-04
US20050070580A1 (en) 2005-03-31
EP1554273A1 (en) 2005-07-20
CA2499105A1 (en) 2004-04-22
JP2006504726A (ja) 2006-02-09
TW200420561A (en) 2004-10-16
WO2004033449A1 (en) 2004-04-22
MXPA05003774A (es) 2005-06-08
US7105547B2 (en) 2006-09-12
AR041556A1 (es) 2005-05-18

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2073 DE 28/09/2010.