BR0314271A - Forma de dosagem oral sólida útil para administração oral transmucosal, e, métodos de reduzir apetências por nicotina, e, uso de tabaco - Google Patents

Forma de dosagem oral sólida útil para administração oral transmucosal, e, métodos de reduzir apetências por nicotina, e, uso de tabaco

Info

Publication number
BR0314271A
BR0314271A BR0314271-0A BR0314271A BR0314271A BR 0314271 A BR0314271 A BR 0314271A BR 0314271 A BR0314271 A BR 0314271A BR 0314271 A BR0314271 A BR 0314271A
Authority
BR
Brazil
Prior art keywords
nicotine
methods
dosage form
transmucosal administration
form useful
Prior art date
Application number
BR0314271-0A
Other languages
English (en)
Inventor
Allan H Graff
Stuart J Platcow
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of BR0314271A publication Critical patent/BR0314271A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Addiction (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"FORMA DE DOSAGEM ORAL SóLIDA úTIL PARA ADMINISTRAçãO ORAL TRANSMUCOSAL, E, MéTODOS DE REDUZIR APETêNCIAS POR NICOTINA, E USO DE TABACO" A presente invenção é direcionada às formas sólidas de dosagem oral de matriz vítrea úteis para administração oral transmucosal de um ativo, como nicotina.
BR0314271-0A 2002-09-16 2003-09-16 Forma de dosagem oral sólida útil para administração oral transmucosal, e, métodos de reduzir apetências por nicotina, e, uso de tabaco BR0314271A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/244,782 US20040052851A1 (en) 2002-09-16 2002-09-16 Modified release oral dosage form
PCT/US2003/029277 WO2004024124A1 (en) 2002-09-16 2003-09-16 Modified release oral dosage form

Publications (1)

Publication Number Publication Date
BR0314271A true BR0314271A (pt) 2005-07-05

Family

ID=31991964

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0314271-0A BR0314271A (pt) 2002-09-16 2003-09-16 Forma de dosagem oral sólida útil para administração oral transmucosal, e, métodos de reduzir apetências por nicotina, e, uso de tabaco

Country Status (10)

Country Link
US (2) US20040052851A1 (pt)
EP (1) EP1553925A4 (pt)
JP (1) JP2006503046A (pt)
CN (1) CN1694686A (pt)
AU (1) AU2003267268B2 (pt)
BR (1) BR0314271A (pt)
CA (1) CA2498930A1 (pt)
MX (1) MXPA05002942A (pt)
NZ (1) NZ539445A (pt)
WO (1) WO2004024124A1 (pt)

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US20030159702A1 (en) * 2002-01-21 2003-08-28 Lindell Katarina E.A. Formulation and use manufacture thereof
CA2523367A1 (en) * 2003-05-02 2004-11-11 Warner-Lambert Company Llc Confectionery products for delivery of pharmaceutically active agents to the throat
GB0320854D0 (en) * 2003-09-05 2003-10-08 Arrow No 7 Ltd Buccal drug delivery
DE602005015446D1 (de) * 2004-06-29 2009-08-27 Fertin Pharma As Tabakalkaloid freisetzendes kaugummi
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
EP1802258A4 (en) 2004-09-13 2015-09-23 Chrono Therapeutics Inc BIOSYNCHRONE TRANSDERMAL MEDICINES
US20070269386A1 (en) * 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
US20070269492A1 (en) * 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
CN101772346B (zh) * 2007-04-02 2014-05-07 帕金森氏病研究院 用于降低治疗副作用的方法和组合物
WO2009074552A2 (en) * 2007-12-11 2009-06-18 Novartis Ag Multi-zone films
AR071420A1 (es) * 2008-05-01 2010-06-16 Smithkline Beecham Corp Composicion de pastilla para chupar oral que comprende un principio activo de nicotina y procedimiento para fabricarla
US9700525B2 (en) 2008-08-20 2017-07-11 Board Of Supervisors Of Louisiana State University And Agricultural & Mechanical College Continuous local slow-release of therapeutics for head and neck problems and upper aerodigestive disorders
US20100055050A1 (en) * 2008-08-30 2010-03-04 Kathleen Moore Nicotine chewing gum on a stick
CA2841785A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US9763928B2 (en) * 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US9044035B2 (en) 2012-04-17 2015-06-02 R.J. Reynolds Tobacco Company Remelted ingestible products
JP6407245B2 (ja) 2013-03-14 2018-10-17 アルトリア クライアント サービシーズ リミテッド ライアビリティ カンパニー ソフトオーラル製品
WO2015068058A1 (en) * 2013-11-06 2015-05-14 Rk Technology & Investments Pte. Ltd. Tobacco free 'niconuts'and the process thereof
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 薬剤送達方法及びシステム
US10679516B2 (en) 2015-03-12 2020-06-09 Morningside Venture Investments Limited Craving input and support system
JP2020503950A (ja) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 経皮薬剤送達の装置及び方法
AU2019279884A1 (en) 2018-05-29 2020-12-10 Morningside Venture Investments Limited Drug delivery methods and systems
CN114609300A (zh) * 2022-04-07 2022-06-10 国家烟草质量监督检验中心 一种基于动物模型评价薄荷醇添加对口含烟烟碱代谢影响的方法

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GB2049417B (en) * 1979-05-29 1983-06-15 Mitra A K Extended release antiacid lozenges
IT1191674B (it) * 1986-03-07 1988-03-23 Eurand Spa Formulazioni per la preparazione di farmaci a rilascio prolungato adatte alla somministrazione per via orale
US4814164A (en) * 1986-03-10 1989-03-21 Colgate-Palmolive Company Solid antitartar mouth deodorant composition
US5525351A (en) * 1989-11-07 1996-06-11 Dam; Anders Nicotine containing stimulant unit
US5048544A (en) * 1990-08-10 1991-09-17 Robert Mascarelli Cigarette substitute
US5167964A (en) * 1992-02-14 1992-12-01 Warner-Lambert Company Semi-enteric drug delivery systems and methods for preparing same
US5549906A (en) * 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
AU4835693A (en) * 1993-08-13 1995-03-14 Rijksuniversiteit Te Groningen Pharmaceutical composition comprising phosphatase or a derivative thereof
PL171939B1 (pl) * 1993-08-16 1997-07-31 Urzadzen Mechanicznych Kamax S Sprzeg, zwlaszcza do pojazdów szynowych PL
US6082368A (en) * 1995-05-08 2000-07-04 Brown; Graham H. Nicotine candy cigarette
DE19606968C2 (de) * 1996-02-24 1998-07-09 Suedzucker Ag Verwendung von 1,1-GPS in Hartkaramellen
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DE19639342C2 (de) * 1996-09-25 1998-07-16 Suedzucker Ag Kaugummi, enthaltend ein Süßungsmittel
US6270804B1 (en) * 1998-04-03 2001-08-07 Biovail Technologies Ltd. Sachet formulations
DE19815327A1 (de) * 1998-04-06 1999-10-07 Soldan Holding & Bonbonspezial Verfahren zur Herstellung von Kau-Pastillen mit Wirkstoff
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US6322806B1 (en) * 1999-04-06 2001-11-27 Wm. Wrigley Jr. Company Over-coated chewing gum formulations including tableted center
DE20102817U1 (de) * 2000-02-23 2001-06-07 Bolder Arzneimittel GmbH, 50968 Köln Lutsch- und Kaupastillen mit Cyclodextrin
JP2004520389A (ja) * 2001-02-08 2004-07-08 ファルマシア・コーポレーション 性的不全の治療のための早期効果発現薬剤
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Also Published As

Publication number Publication date
AU2003267268A1 (en) 2004-04-30
MXPA05002942A (es) 2006-01-24
EP1553925A4 (en) 2012-09-05
US20040076665A1 (en) 2004-04-22
NZ539445A (en) 2007-03-30
JP2006503046A (ja) 2006-01-26
CA2498930A1 (en) 2004-03-25
WO2004024124A1 (en) 2004-03-25
US20040052851A1 (en) 2004-03-18
CN1694686A (zh) 2005-11-09
EP1553925A1 (en) 2005-07-20
AU2003267268B2 (en) 2007-03-15

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: A61K 9/14

Ipc: A61K 9/20 (2006.01)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8, 10, 11, 13 E 25 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.

B15K Others concerning applications: alteration of classification

Ipc: A61K 9/20 (2006.01)