BR0312000A - Compostos, composições farmacêuticas, método para o tratamento ou profilaxia de doenças, e, uso dos compostos - Google Patents
Compostos, composições farmacêuticas, método para o tratamento ou profilaxia de doenças, e, uso dos compostosInfo
- Publication number
- BR0312000A BR0312000A BR0312000-7A BR0312000A BR0312000A BR 0312000 A BR0312000 A BR 0312000A BR 0312000 A BR0312000 A BR 0312000A BR 0312000 A BR0312000 A BR 0312000A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- pharmaceutical compositions
- diseases
- prophylaxis
- treating
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 7
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title 1
- VSWICNJIUPRZIK-UHFFFAOYSA-N 2-piperideine Chemical class C1CNC=CC1 VSWICNJIUPRZIK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002461 renin inhibitor Substances 0.000 abstract 1
- 229940086526 renin-inhibitors Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP0207102 | 2002-06-27 | ||
| PCT/EP2003/004445 WO2004002957A1 (en) | 2002-06-27 | 2003-04-29 | Novel tetrahydropyridine derivatives as renin inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0312000A true BR0312000A (pt) | 2005-03-22 |
Family
ID=29797098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0312000-7A BR0312000A (pt) | 2002-06-27 | 2003-04-29 | Compostos, composições farmacêuticas, método para o tratamento ou profilaxia de doenças, e, uso dos compostos |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20060009497A1 (enExample) |
| EP (1) | EP1519920A1 (enExample) |
| JP (1) | JP2005532371A (enExample) |
| CN (1) | CN1662498A (enExample) |
| AU (1) | AU2003229746A1 (enExample) |
| BR (1) | BR0312000A (enExample) |
| CA (1) | CA2490138A1 (enExample) |
| CL (1) | CL2003002043A1 (enExample) |
| IL (1) | IL165887A0 (enExample) |
| MX (1) | MXPA04012136A (enExample) |
| NO (1) | NO20050290L (enExample) |
| PL (1) | PL375214A1 (enExample) |
| RU (1) | RU2005102002A (enExample) |
| TW (1) | TW200514772A (enExample) |
| WO (1) | WO2004002957A1 (enExample) |
| ZA (1) | ZA200408423B (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060217371A1 (en) * | 2003-04-28 | 2006-09-28 | Olivier Bezencon | Diazabicyclononene and tetrahydropyriddine derivatives as renin inhibitors |
| MXPA05011478A (es) * | 2003-04-29 | 2005-12-12 | Actelion Pharmaceuticals Ltd | Derivados de 1,2,3,6-tetrahidropiridina 3,4-disustituidos novedosos. |
| CA2521938A1 (en) * | 2003-04-30 | 2004-11-11 | Actelion Pharmaceuticals Ltd | 9-azabicyclo[3.3.1]non-6-ene derivatives with a heteroatom at the 3-position as renin inhibitors |
| EP1622564A2 (en) * | 2003-05-02 | 2006-02-08 | Actelion Pharmaceuticals Ltd. | Diazabicyclononene derivatives |
| WO2004105738A2 (en) * | 2003-05-30 | 2004-12-09 | Actelion Pharmaceuticals Ltd | Use of tetrahydropyridine derivatives |
| CN1863773A (zh) * | 2003-10-09 | 2006-11-15 | 埃科特莱茵药品有限公司 | 四氢吡啶衍生物 |
| JP2007508262A (ja) * | 2003-10-13 | 2007-04-05 | アクテリオン ファマシューティカルズ リミテッド | 新規ジアザビシクロノネン誘導体およびその使用 |
| US20070111989A1 (en) * | 2003-12-05 | 2007-05-17 | Olivier Bezencon | Novel diazabicyclononene derivatives and use |
| WO2005068427A1 (ja) * | 2004-01-14 | 2005-07-28 | Takeda Pharmaceutical Company Limited | カルボキサミド誘導体およびその用途 |
| RU2426532C2 (ru) * | 2004-03-17 | 2011-08-20 | Новартис Аг | Применение органических соединений |
| CA2577084A1 (en) | 2004-08-25 | 2006-03-02 | Olivier Bezencon | Bicyclononene derivatives as renin inhibitors |
| GB0428526D0 (en) * | 2004-12-30 | 2005-02-09 | Novartis Ag | Organic compounds |
| GB0500784D0 (en) * | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
| GB0504850D0 (en) * | 2005-03-09 | 2005-04-13 | Novartis Ag | Organic compounds |
| GB0510810D0 (en) * | 2005-05-26 | 2005-06-29 | Novartis Ag | Organic compounds |
| AU2006253805A1 (en) * | 2005-05-27 | 2006-12-07 | Actelion Pharmaceuticals Ltd. | Novel piperidine carboxylic acid amide derivatives |
| GB0514203D0 (en) | 2005-07-11 | 2005-08-17 | Novartis Ag | Organic compounds |
| WO2007049224A1 (en) * | 2005-10-25 | 2007-05-03 | Actelion Pharmaceuticals Ltd | Novel hexahydro- or octahydro-cyclopenta[c]pyrrole derivatives |
| RU2425032C2 (ru) | 2006-02-02 | 2011-07-27 | Актелион Фармасьютикалз Лтд | Вторичные амины в качестве ингибиторов ренина |
| CA2642424A1 (en) * | 2006-03-03 | 2007-09-07 | Actelion Pharmaceuticals Ltd. | Primary amines as renin inhibitors |
| NZ571595A (en) * | 2006-03-08 | 2010-06-25 | Actelion Pharmaceuticals Ltd | New amines |
| EP1908471A1 (en) * | 2006-10-04 | 2008-04-09 | Speedel Experimenta AG | Tetrahydropyridines as renin inhibitors |
| AU2008253519A1 (en) | 2007-05-24 | 2008-11-27 | Merck Frosst Canada Ltd | Novel case of renin inhibitors |
| EP2190811B1 (en) | 2007-08-20 | 2013-08-07 | Merck Canada Inc. | Renin inhibitors |
| US8889714B2 (en) | 2008-05-05 | 2014-11-18 | Actelion Pharmaceuticals Ltd. | 3,4-substituted piperidine derivatives as renin inhibitors |
| TWI471289B (zh) | 2010-06-11 | 2015-02-01 | Rhodes Technologies | 使三級胺進行ｎ－脫烷反應之方法 |
| CA2936749C (en) | 2010-06-11 | 2019-07-09 | Rhodes Technologies | Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof |
| CN117865941B (zh) * | 2024-03-13 | 2024-06-28 | 上海方予健康医药科技有限公司 | 取代哌啶化合物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5376666A (en) * | 1992-11-30 | 1994-12-27 | The Du Pont Merck Pharmaceutical Company | Angiotension-II receptor blocking, azacycloalkyl or azacycloalkenyl |
| PL193686B1 (pl) * | 1995-09-07 | 2007-03-30 | Hoffmann La Roche | Pochodne piperydyny, środki lecznicze zawierającepochodne piperydyny, sposoby wytwarzania tych pochodnych oraz zastosowanie pochodnych |
| US6376672B1 (en) * | 1999-04-27 | 2002-04-23 | Hoffmann-La Roche Inc. | Naphthalenylmethoxypiperidines as renin inhibitors |
-
2003
- 2003-04-29 MX MXPA04012136A patent/MXPA04012136A/es unknown
- 2003-04-29 AU AU2003229746A patent/AU2003229746A1/en not_active Abandoned
- 2003-04-29 US US10/514,164 patent/US20060009497A1/en not_active Abandoned
- 2003-04-29 RU RU2005102002/04A patent/RU2005102002A/ru not_active Application Discontinuation
- 2003-04-29 WO PCT/EP2003/004445 patent/WO2004002957A1/en not_active Ceased
- 2003-04-29 BR BR0312000-7A patent/BR0312000A/pt not_active IP Right Cessation
- 2003-04-29 CA CA002490138A patent/CA2490138A1/en not_active Abandoned
- 2003-04-29 EP EP03722566A patent/EP1519920A1/en not_active Withdrawn
- 2003-04-29 CN CN038138875A patent/CN1662498A/zh active Pending
- 2003-04-29 PL PL03375214A patent/PL375214A1/xx not_active Application Discontinuation
- 2003-04-29 JP JP2004516551A patent/JP2005532371A/ja active Pending
- 2003-10-10 CL CL200302043A patent/CL2003002043A1/es unknown
- 2003-10-28 TW TW092129927A patent/TW200514772A/zh unknown
-
2004
- 2004-10-18 ZA ZA200408423A patent/ZA200408423B/xx unknown
- 2004-12-21 IL IL16588704A patent/IL165887A0/xx unknown
-
2005
- 2005-01-19 NO NO20050290A patent/NO20050290L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL375214A1 (en) | 2005-11-28 |
| NO20050290L (no) | 2005-01-19 |
| TW200514772A (en) | 2005-05-01 |
| ZA200408423B (en) | 2005-10-11 |
| US20060009497A1 (en) | 2006-01-12 |
| CL2003002043A1 (es) | 2005-01-28 |
| RU2005102002A (ru) | 2005-09-20 |
| MXPA04012136A (es) | 2005-04-19 |
| EP1519920A1 (en) | 2005-04-06 |
| WO2004002957A1 (en) | 2004-01-08 |
| AU2003229746A1 (en) | 2004-01-19 |
| CN1662498A (zh) | 2005-08-31 |
| JP2005532371A (ja) | 2005-10-27 |
| CA2490138A1 (en) | 2004-01-08 |
| IL165887A0 (en) | 2006-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A,5A,6A E 7A ANUIDADES |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2064 DE 27/07/2010. |