BR0309152A - composto ou sais, solvatos, hidratos ou pró-drogas deste farmaceuticamente aceitáveis, composição, métodos para tratar ou prevenir uma doença ou condição, uma doença cardiovascular, uma dislipidemia, a hipertensão, o cáncer, a inflamação, e a impotência em um paciente, forma de dosagem unitária, e, método para identificar um composto útil para tratar ou prevenir uma condição em um paciente - Google Patents

composto ou sais, solvatos, hidratos ou pró-drogas deste farmaceuticamente aceitáveis, composição, métodos para tratar ou prevenir uma doença ou condição, uma doença cardiovascular, uma dislipidemia, a hipertensão, o cáncer, a inflamação, e a impotência em um paciente, forma de dosagem unitária, e, método para identificar um composto útil para tratar ou prevenir uma condição em um paciente

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Publication number
BR0309152A
BR0309152A BRPI0309152-0A BR0309152A BR0309152A BR 0309152 A BR0309152 A BR 0309152A BR 0309152 A BR0309152 A BR 0309152A BR 0309152 A BR0309152 A BR 0309152A
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BR
Brazil
Prior art keywords
treating
disease
preventing
patient
condition
Prior art date
Application number
BRPI0309152-0A
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English (en)
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Esperion Therapeutics Inc
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Publication date
Application filed by Esperion Therapeutics Inc filed Critical Esperion Therapeutics Inc
Publication of BR0309152A publication Critical patent/BR0309152A/pt

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  • Obesity (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Reproductive Health (AREA)

Abstract

"COMPOSTO OU SAIS, SOLVATOS, HIDRATOS OU PRó-DROGAS DESTE FARMACEUTICAMENTE ACEITáVEIS, COMPOSIçãO, MéTODOS PARA TRATAR OU PREVENIR UMA DOENçA OU CONDIçãO, UMA DOENçA CARDIOVASCULAR, UMA DISLIPIDEMIA, A HIPERTENSãO, O CáNCER, A INFLAMAçãO, E A IMPOTêNCIA EM UM PACIENTE, FORMA DE DOSAGEM UNITáRIA, E, MéTODO PARA IDENTIFICAR UM COMPOSTO úTIL PARA TRATAR OU PREVENIR UMA CONDIçãO EM UM PACIENTE". A invenção diz respeito a novas imitações da Acil coenzima A, às composições que compreendem os compostos de cetona e aos métodos úteis para tratar e prevenir doenças cardiovasculares, dislipidemias, disproteinemias e distúrbios do metabolismo de glicose que compreendem administrar uma composição que compreende um composto de cetona. As imitações da Acil coenzima A, as composições e métodos da invenção também são úteis para tratar e prevenir o Mal de Alzheimer, a Síndrome X, os distúrbios relacionados com o receptor ativado do proliferador de peroxissoma, a septicemia, os distúrbios trombóticos, a obesidade, a pancreatite, a hipertensão, a doença renal, o câncer, a inflamação, a infecção bacteriana e a impotência. Em certas formas de realização, as imitações da Acil coenzima A, as composições e métodos da invenção são úteis na terapia de combinação com outros produtos terapêuticos, tais como agentes hipocolesterolêmicos e hipoglicêmicos.
BRPI0309152-0A 2002-04-10 2003-04-10 composto ou sais, solvatos, hidratos ou pró-drogas deste farmaceuticamente aceitáveis, composição, métodos para tratar ou prevenir uma doença ou condição, uma doença cardiovascular, uma dislipidemia, a hipertensão, o cáncer, a inflamação, e a impotência em um paciente, forma de dosagem unitária, e, método para identificar um composto útil para tratar ou prevenir uma condição em um paciente BR0309152A (pt)

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US37151102P 2002-04-10 2002-04-10
PCT/US2003/011467 WO2003087108A2 (en) 2002-04-10 2003-04-10 Mimics of acyl coenzyme-a, compositions thereof, and methods of cholesterol management and related uses

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US (2) US20030236212A1 (pt)
EP (2) EP1495034A2 (pt)
JP (2) JP2005522509A (pt)
AU (2) AU2003230918A1 (pt)
BR (1) BR0309152A (pt)
CA (2) CA2480410A1 (pt)
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AU2003221926A1 (en) 2003-10-27
CA2480410A1 (en) 2003-10-23
WO2003087108A3 (en) 2004-07-15
JP2005522504A (ja) 2005-07-28
MXPA04009831A (es) 2004-12-07
US20030236213A1 (en) 2003-12-25
WO2003087040A3 (en) 2004-07-15
AU2003221926A8 (en) 2003-10-27
WO2003087108A2 (en) 2003-10-23
CA2480415A1 (en) 2003-10-23
US20030236212A1 (en) 2003-12-25
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EP1495034A2 (en) 2005-01-12
MXPA04009832A (es) 2004-12-07

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