BR0307938A - Processo para a produção de triglicerìdeos compreendendo ácidos graxos insaturados, triglicerìdeo, uso do mesmo, polipeptìdeo com atividade e-11 desaturase, sequência de ácido nucleico, cassete de expressão recombinante, vetor de expressão recombinante, e organismo transgênico - Google Patents
Processo para a produção de triglicerìdeos compreendendo ácidos graxos insaturados, triglicerìdeo, uso do mesmo, polipeptìdeo com atividade e-11 desaturase, sequência de ácido nucleico, cassete de expressão recombinante, vetor de expressão recombinante, e organismo transgênicoInfo
- Publication number
- BR0307938A BR0307938A BR0307938-4A BR0307938A BR0307938A BR 0307938 A BR0307938 A BR 0307938A BR 0307938 A BR0307938 A BR 0307938A BR 0307938 A BR0307938 A BR 0307938A
- Authority
- BR
- Brazil
- Prior art keywords
- recombinant expression
- fatty acids
- triglycerides
- production
- unsaturated fatty
- Prior art date
Links
- 238000003259 recombinant expression Methods 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 150000003626 triacylglycerols Chemical class 0.000 title abstract 3
- 235000021122 unsaturated fatty acids Nutrition 0.000 title abstract 3
- 150000004670 unsaturated fatty acids Chemical class 0.000 title abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- 150000007523 nucleic acids Chemical group 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000009261 transgenic effect Effects 0.000 title abstract 2
- 239000013604 expression vector Substances 0.000 title 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 title 1
- 241000238631 Hexapoda Species 0.000 abstract 2
- 241000255777 Lepidoptera Species 0.000 abstract 2
- JBYXPOFIGCOSSB-GOJKSUSPSA-N 9-cis,11-trans-octadecadienoic acid Chemical compound CCCCCC\C=C\C=C/CCCCCCCC(O)=O JBYXPOFIGCOSSB-GOJKSUSPSA-N 0.000 abstract 1
- 241000195493 Cryptophyta Species 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 229940108924 conjugated linoleic acid Drugs 0.000 abstract 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 abstract 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Nutrition Science (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Fats And Perfumes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
"PROCESSO PARA A PRODUçãO DE TRIGLICERìDEOS COMPREENDENDO áCIDOS GRAXOS INSATURADOS, TRIGLICERìDEO, USO DO MESMO, POLIPEPTìDEO COM ATIVIDADE E-11 DESATURASE, SEQuêNCIA DE áCIDO NUCLEICO, CASSETE DE EXPRESSãO RECOMBINANTE, VETOR DE EXPRESSãO RECOMBINANTE, E ORGANISMO TRANSGêNICO". A invenção refere-se a processos para a produção de ácidos graxos insaturados, preferivelmente de ácidos graxos poliinsaturados conjugados como ácido linoleico conjugado, (CLA) pela expressão recombinante de desaturases de insetos da ordem Lepidoptera. A expressão preferivelmente ocorre em um organismo selecionado dentre o grupo de organismos de plantas, leveduras, fungos e algas. Também de acordo com a invenção são os cassetes de expressão recombinantes para a expressão recombinante de desaturases de insetos da ordem Lepidoptera, e os organismos transgênicos transformados com os mesmos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10208812A DE10208812A1 (de) | 2002-03-01 | 2002-03-01 | Verfahren zur Herstellung von ungesättigten Fettsäuren |
PCT/US2003/005788 WO2003074715A2 (en) | 2002-03-01 | 2003-02-27 | Process for the production of unsaturated fatty acids |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0307938A true BR0307938A (pt) | 2005-01-11 |
Family
ID=27740519
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0307938-4A BR0307938A (pt) | 2002-03-01 | 2003-02-27 | Processo para a produção de triglicerìdeos compreendendo ácidos graxos insaturados, triglicerìdeo, uso do mesmo, polipeptìdeo com atividade e-11 desaturase, sequência de ácido nucleico, cassete de expressão recombinante, vetor de expressão recombinante, e organismo transgênico |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1527182A4 (pt) |
JP (1) | JP2006503546A (pt) |
CN (1) | CN1656226A (pt) |
AU (2) | AU2003208769A1 (pt) |
BR (1) | BR0307938A (pt) |
CA (1) | CA2477858A1 (pt) |
DE (1) | DE10208812A1 (pt) |
WO (2) | WO2003074715A2 (pt) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2421440T3 (es) * | 2004-02-27 | 2013-09-02 | Basf Plant Science Gmbh | Método para preparar ácidos grasos poliinsaturados en plantas transgénicas |
DE102005052551A1 (de) * | 2005-11-02 | 2007-05-16 | Rothamsted Res Harpenden | Verfahren zur Herstellung von y-Linolensäure und/oder Stearidonsäure in transgenen Brassicaceae und Linaceae |
DK1976877T4 (en) | 2005-11-30 | 2017-01-16 | Abbvie Inc | Monoclonal antibodies to amyloid beta protein and uses thereof |
PL1954718T3 (pl) | 2005-11-30 | 2015-04-30 | Abbvie Inc | Przeciwciała skierowane przeciwko A globulomerowi, ich reszty wiążące antygeny, odpowiednie hybrydomy, kwasy nukleinowe, wektory, komórki gospodarze, sposoby wytwarzania tych przeciwciał, kompozycje zawierające te przeciwciała, zastosowania tych przeciwciał i sposoby stosowania tych przeciwciał |
CN101617039A (zh) * | 2006-10-20 | 2009-12-30 | 代表亚利桑那大学的亚利桑那校董会 | 经修饰的蓝细菌 |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
PT2367950T (pt) * | 2008-12-01 | 2017-07-06 | Univ Saarland | Produção de ácidos gordos ómega-3 por mixobactérias |
JP5168511B2 (ja) * | 2009-08-25 | 2013-03-21 | 独立行政法人農業生物資源研究所 | 種子特異的プロモーターおよびその利用 |
JP2013523182A (ja) | 2010-04-15 | 2013-06-17 | アボット・ラボラトリーズ | アミロイドベータ結合タンパク質 |
US11236351B2 (en) | 2010-05-17 | 2022-02-01 | Dow Agrosciences Llc | Production of DHA and other LC PUFAs in plants |
EP2603524A1 (en) | 2010-08-14 | 2013-06-19 | AbbVie Inc. | Amyloid-beta binding proteins |
TW201307553A (zh) | 2011-07-26 | 2013-02-16 | Dow Agrosciences Llc | 在植物中生產二十二碳六烯酸(dha)及其他長鏈多元不飽和脂肪酸(lc-pufa)之技術 |
KR101540746B1 (ko) | 2011-12-28 | 2015-08-03 | 대한민국 | 공액리놀레산(Conjugated Linoleic Acid, CLA)의 생산방법 |
CN108138202B (zh) | 2015-06-26 | 2023-05-16 | 丹麦科技大学 | 用于在酵母中产生蛾信息素的方法 |
WO2017087846A1 (en) | 2015-11-18 | 2017-05-26 | Provivi, Inc. | Microorganisms for the production of insect pheromones and related compounds |
AR110606A1 (es) | 2016-06-06 | 2019-04-17 | Provivi Inc | Producción semi-biosintética de alcoholes grasos y aldehídos grasos |
DE17825464T1 (de) | 2016-12-16 | 2019-12-19 | Danmarks Tekniske Universitet | Verfahren zur herstellung von fettalkoholen und derivaten davon in hefe |
US11434506B2 (en) | 2016-12-16 | 2022-09-06 | Danmarks Tekniske Universitet | Production of desaturated fatty alcohols and desaturated fatty alcohol acetates in yeast |
AR112543A1 (es) | 2017-05-17 | 2019-11-13 | Provivi Inc | Microorganismos para la producción de feromonas de insectos y compuestos relacionados |
EP3521439A1 (en) * | 2018-01-31 | 2019-08-07 | Commissariat à l'Energie Atomique et aux Energies Alternatives | Method for the production of triacylglycerides and fatty acids |
CN116064266B (zh) * | 2022-11-01 | 2024-06-14 | 四川大学 | 盐胁迫抗性增强的重组酿酒酵母菌及其构建方法与应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0866874B2 (en) * | 1995-11-14 | 2005-06-22 | Loders Croklaan B.V. | Process for the preparation of materials with a high content of isomers of conjugated linoleic acid |
US5876994A (en) * | 1995-11-16 | 1999-03-02 | Cornell Research Foundation, Inc. | Pheromone desaturases |
EP0915909B1 (en) * | 1997-05-05 | 2007-06-13 | Dow AgroSciences LLC | Insecticidal protein toxins from xenorhabdus |
KR100619651B1 (ko) * | 1998-03-17 | 2006-09-05 | 콘린코 인크. | 공액 리놀레산 조성물 |
AU4564399A (en) * | 1998-06-12 | 1999-12-30 | Abbott Laboratories | Polyunsaturated fatty acids in plants |
AU5785199A (en) * | 1998-08-24 | 2000-03-14 | Rutgers, The State University Of New Jersey | Synthetic fatty acid desaturase gene for expression in plants |
US6706501B1 (en) * | 1999-06-30 | 2004-03-16 | Arkion Life Sciences Llc | Polynucleotide encoding a propionibacterium linoleate isomerase and uses thereof |
WO2001002591A1 (de) * | 1999-07-06 | 2001-01-11 | Basf Plant Science Gmbh | Δ6-desaturasegene exprimierende pflanzen und pufas enthaltende öle aus diesen pflanzen und ein verfahren zur herstellung ungesättigter fettsäuren |
AU2001263473A1 (en) * | 2000-05-26 | 2001-12-11 | Washington State University Research Foundation | Palmitate desaturase gene |
-
2002
- 2002-03-01 DE DE10208812A patent/DE10208812A1/de not_active Withdrawn
-
2003
- 2003-02-27 CA CA002477858A patent/CA2477858A1/en not_active Abandoned
- 2003-02-27 CN CNA038050625A patent/CN1656226A/zh active Pending
- 2003-02-27 BR BR0307938-4A patent/BR0307938A/pt not_active IP Right Cessation
- 2003-02-27 WO PCT/US2003/005788 patent/WO2003074715A2/en active Application Filing
- 2003-02-27 WO PCT/EP2003/002011 patent/WO2003074716A2/de not_active Application Discontinuation
- 2003-02-27 EP EP03716183A patent/EP1527182A4/en not_active Withdrawn
- 2003-02-27 AU AU2003208769A patent/AU2003208769A1/en not_active Abandoned
- 2003-02-27 JP JP2003573162A patent/JP2006503546A/ja active Pending
- 2003-02-27 AU AU2003219899A patent/AU2003219899A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE10208812A1 (de) | 2003-09-11 |
AU2003219899A1 (en) | 2003-09-16 |
CA2477858A1 (en) | 2003-09-12 |
CN1656226A (zh) | 2005-08-17 |
EP1527182A4 (en) | 2005-12-21 |
WO2003074715A3 (en) | 2004-04-29 |
WO2003074716A2 (de) | 2003-09-12 |
AU2003208769A1 (en) | 2003-09-16 |
AU2003208769A8 (en) | 2003-09-16 |
WO2003074716A3 (de) | 2003-12-24 |
WO2003074715A2 (en) | 2003-09-12 |
EP1527182A2 (en) | 2005-05-04 |
JP2006503546A (ja) | 2006-02-02 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 6A. E 7A. ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2051 DE 27/04/2010. |