BR0307339A - Metabolitos de ácido (3-{[(4-terc-butil-benzil)-(piridina-3-sulfonil)-amino]-m etil}-fenóxi)-acético - Google Patents
Metabolitos de ácido (3-{[(4-terc-butil-benzil)-(piridina-3-sulfonil)-amino]-m etil}-fenóxi)-acéticoInfo
- Publication number
- BR0307339A BR0307339A BR0307339-4A BR0307339A BR0307339A BR 0307339 A BR0307339 A BR 0307339A BR 0307339 A BR0307339 A BR 0307339A BR 0307339 A BR0307339 A BR 0307339A
- Authority
- BR
- Brazil
- Prior art keywords
- phenoxy
- pyridine
- benzyl
- butyl
- amino
- Prior art date
Links
- WOHRHWDYFNWPNG-UHFFFAOYSA-N evatanepag Chemical class C1=CC(C(C)(C)C)=CC=C1CN(S(=O)(=O)C=1C=NC=CC=1)CC1=CC=CC(OCC(O)=O)=C1 WOHRHWDYFNWPNG-UHFFFAOYSA-N 0.000 title abstract 2
- -1 PYRIDINE-3-SULPHONYL Chemical class 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C07D213/71—Sulfur atoms to which a second hetero atom is attached
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
"METABOLITOS DE áCIDO (3-{[(4-TERC-BUTIL-BENZIL)-(PIRIDINA-3-SULFONIL)-AMINO]-M ETIL)-FENóXI)-ACéTICO". A presente invenção refere-se a metabolitos de ácido (3-{[(4-terc-butil-benzil)-(piridina-3-sulfonil)-amino]-metil}-fenóxi)-acéti co.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35374802P | 2002-01-31 | 2002-01-31 | |
| PCT/IB2003/000121 WO2003064391A1 (en) | 2002-01-31 | 2003-01-20 | Metabolites of (3-{[4-tert-butyl-benzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0307339A true BR0307339A (pt) | 2004-12-07 |
Family
ID=27663249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0307339-4A BR0307339A (pt) | 2002-01-31 | 2003-01-20 | Metabolitos de ácido (3-{[(4-terc-butil-benzil)-(piridina-3-sulfonil)-amino]-m etil}-fenóxi)-acético |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US6852863B2 (pt) |
| EP (1) | EP1470109A1 (pt) |
| JP (1) | JP2005521668A (pt) |
| KR (1) | KR20040077884A (pt) |
| CN (1) | CN1625549A (pt) |
| AP (1) | AP2004003094A0 (pt) |
| AR (1) | AR038332A1 (pt) |
| BR (1) | BR0307339A (pt) |
| CA (1) | CA2473984A1 (pt) |
| EA (1) | EA200400724A1 (pt) |
| EC (1) | ECSP045215A (pt) |
| GB (1) | GB2400100B (pt) |
| HN (1) | HN2003000051A (pt) |
| HR (1) | HRP20040683A2 (pt) |
| HU (1) | HUP0500012A2 (pt) |
| IL (1) | IL162167A0 (pt) |
| IS (1) | IS7281A (pt) |
| MA (1) | MA27169A1 (pt) |
| MX (1) | MXPA04004960A (pt) |
| NO (1) | NO20043569D0 (pt) |
| OA (1) | OA12760A (pt) |
| PA (1) | PA8564601A1 (pt) |
| PE (1) | PE20030978A1 (pt) |
| PL (1) | PL371982A1 (pt) |
| TN (1) | TNSN04138A1 (pt) |
| TW (1) | TW200302080A (pt) |
| UY (1) | UY27632A1 (pt) |
| WO (1) | WO2003064391A1 (pt) |
| ZA (1) | ZA200404067B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA67754C2 (uk) * | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
| US7666330B2 (en) * | 2005-04-20 | 2010-02-23 | Lg Chem, Ltd. | Additive for non-aqueous electrolyte and secondary battery using the same |
| EP2059507B1 (en) * | 2006-07-28 | 2013-03-20 | Pfizer Products Inc. | Ep2 agonist |
| CN101669030B (zh) | 2007-03-08 | 2016-01-13 | 小利兰·斯坦福大学托管委员会 | 线粒体醛脱氢酶2调节剂和其使用方法 |
| EP2002834A1 (de) * | 2007-06-13 | 2008-12-17 | Bayer Schering Pharma Aktiengesellschaft | Aryl/Hetarylamide als Modulatoren des EP2-Rezeptors |
| WO2009113600A1 (ja) * | 2008-03-12 | 2009-09-17 | 宇部興産株式会社 | ピリジルアミノ酢酸化合物 |
| EP2149554A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma Aktiengesellschaft | Indolylamide als Modulatoren des EP2-Rezeptors |
| EP2149552A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | 5,6 substituierte Benzamid-Derivate als Modulatoren des EP2-Rezeptors |
| EP2149551A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | N-(Indol-3-ylalkyl)-(hetero)arylamidderivate als Modulatoren des EP2-Rezeptors |
| WO2010028175A1 (en) * | 2008-09-08 | 2010-03-11 | The Board Of Trustees Of The Leland Stanford Junior University | Modulators of aldehyde dehydrogenase activity and methods of use thereof |
| EP2349279A4 (en) | 2008-10-28 | 2013-12-25 | Univ Leland Stanford Junior | ALDEHYDE DEHYDROGENASE MODULATORS AND METHOD OF USE THEREOF |
| DK2415763T3 (en) | 2009-03-30 | 2016-03-07 | Ube Industries | A pharmaceutical composition for the treatment or prevention of glaucoma |
| DE102009049662A1 (de) | 2009-10-13 | 2011-04-14 | Bayer Schering Pharma Aktiengesellschaft | 2,5-Disubstituierte 2H-Indazole als EP2-Rezeptor-Antagonisten |
| US10457659B2 (en) | 2011-04-29 | 2019-10-29 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for increasing proliferation of adult salivary stem cells |
| TW201326154A (zh) | 2011-11-28 | 2013-07-01 | 拜耳知識產權公司 | 作為ｅｐ２受體拮抗劑之新穎２ｈ－吲唑 |
| EP2970124B1 (en) | 2013-03-14 | 2019-05-22 | The Board of Trustees of the Leland Stanford Junior University | Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA67754C2 (uk) * | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
-
2003
- 2003-01-20 EP EP03700072A patent/EP1470109A1/en not_active Withdrawn
- 2003-01-20 PL PL03371982A patent/PL371982A1/xx not_active Application Discontinuation
- 2003-01-20 JP JP2003564014A patent/JP2005521668A/ja active Pending
- 2003-01-20 GB GB0413967A patent/GB2400100B/en not_active Expired - Fee Related
- 2003-01-20 EA EA200400724A patent/EA200400724A1/ru unknown
- 2003-01-20 AP APAP/P/2004/003094A patent/AP2004003094A0/en unknown
- 2003-01-20 WO PCT/IB2003/000121 patent/WO2003064391A1/en active Application Filing
- 2003-01-20 OA OA1200400198A patent/OA12760A/en unknown
- 2003-01-20 BR BR0307339-4A patent/BR0307339A/pt not_active IP Right Cessation
- 2003-01-20 CN CNA038029952A patent/CN1625549A/zh active Pending
- 2003-01-20 MX MXPA04004960A patent/MXPA04004960A/es unknown
- 2003-01-20 IL IL16216703A patent/IL162167A0/xx unknown
- 2003-01-20 HU HU0500012A patent/HUP0500012A2/hu unknown
- 2003-01-20 CA CA002473984A patent/CA2473984A1/en not_active Abandoned
- 2003-01-20 KR KR10-2004-7011618A patent/KR20040077884A/ko not_active Application Discontinuation
- 2003-01-24 TW TW092101619A patent/TW200302080A/zh unknown
- 2003-01-28 HN HN2003000051A patent/HN2003000051A/es unknown
- 2003-01-28 PE PE2003000086A patent/PE20030978A1/es not_active Application Discontinuation
- 2003-01-29 US US10/353,671 patent/US6852863B2/en not_active Expired - Fee Related
- 2003-01-29 AR ARP030100254A patent/AR038332A1/es unknown
- 2003-01-30 UY UY27632A patent/UY27632A1/es not_active Application Discontinuation
- 2003-01-30 PA PA20038564601A patent/PA8564601A1/es unknown
-
2004
- 2004-05-21 IS IS7281A patent/IS7281A/is unknown
- 2004-05-25 ZA ZA200404067A patent/ZA200404067B/en unknown
- 2004-07-21 MA MA27796A patent/MA27169A1/fr unknown
- 2004-07-23 HR HR20040683A patent/HRP20040683A2/hr not_active Application Discontinuation
- 2004-07-27 TN TNP2004000138A patent/TNSN04138A1/fr unknown
- 2004-07-30 EC EC2004005215A patent/ECSP045215A/es unknown
- 2004-08-26 NO NO20043569A patent/NO20043569D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB2400100B (en) | 2006-04-12 |
| MA27169A1 (fr) | 2005-01-03 |
| UY27632A1 (es) | 2003-08-29 |
| EP1470109A1 (en) | 2004-10-27 |
| PE20030978A1 (es) | 2003-11-19 |
| IS7281A (is) | 2004-05-21 |
| HUP0500012A2 (hu) | 2005-04-28 |
| MXPA04004960A (es) | 2005-04-08 |
| GB0413967D0 (en) | 2004-07-28 |
| PA8564601A1 (es) | 2003-09-05 |
| NO20043569L (no) | 2004-08-26 |
| AP2004003094A0 (en) | 2004-09-30 |
| TNSN04138A1 (fr) | 2007-03-12 |
| KR20040077884A (ko) | 2004-09-07 |
| TW200302080A (en) | 2003-08-01 |
| CN1625549A (zh) | 2005-06-08 |
| US6852863B2 (en) | 2005-02-08 |
| PL371982A1 (en) | 2005-07-11 |
| AR038332A1 (es) | 2005-01-12 |
| ZA200404067B (en) | 2005-08-29 |
| HRP20040683A2 (en) | 2004-10-31 |
| IL162167A0 (en) | 2005-11-20 |
| WO2003064391A1 (en) | 2003-08-07 |
| JP2005521668A (ja) | 2005-07-21 |
| HN2003000051A (es) | 2003-09-24 |
| ECSP045215A (es) | 2004-09-28 |
| CA2473984A1 (en) | 2003-08-07 |
| NO20043569D0 (no) | 2004-08-26 |
| OA12760A (en) | 2006-07-04 |
| EA200400724A1 (ru) | 2004-12-30 |
| US20030216445A1 (en) | 2003-11-20 |
| GB2400100A (en) | 2004-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2051 DE 27/04/2010. |