BR0215337A - Piperidina-2, 6-dionas heretociclicamente substituìda na 3-posição - Google Patents

Piperidina-2, 6-dionas heretociclicamente substituìda na 3-posição

Info

Publication number
BR0215337A
BR0215337A BR0215337-8A BR0215337A BR0215337A BR 0215337 A BR0215337 A BR 0215337A BR 0215337 A BR0215337 A BR 0215337A BR 0215337 A BR0215337 A BR 0215337A
Authority
BR
Brazil
Prior art keywords
diones
piperidine
heretocyclically
substituted
diseases
Prior art date
Application number
BR0215337-8A
Other languages
English (en)
Inventor
Helmut Heinrich Buschmann
Tieno Germann
Oswald Zimmer
Stefanie Frosch
Fritz Theil
Original Assignee
Gr Nenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gr Nenthal Gmbh filed Critical Gr Nenthal Gmbh
Publication of BR0215337A publication Critical patent/BR0215337A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"PIPERIDINA-2, 6-DIONAS HERETOCICLICAMENTE SUBSTITUìDA NA 3-POSIçãO". E com a sua produção e o uso em medicamentos, em particular como imunomoduladores para o tratamento e/ou profilaxia de doenças inflamatórias e auto-imunes, em adição a doenças oncológicas em hematologia.
BR0215337-8A 2001-12-21 2002-12-18 Piperidina-2, 6-dionas heretociclicamente substituìda na 3-posição BR0215337A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10163595A DE10163595A1 (de) 2001-12-21 2001-12-21 In 3-Position heterocyclisch substituierte Piperidin-2,6-dione
PCT/EP2002/014447 WO2003053956A1 (de) 2001-12-21 2002-12-18 In 3-position heterocyclisch substituierte piperidin-2,6-dione

Publications (1)

Publication Number Publication Date
BR0215337A true BR0215337A (pt) 2004-11-16

Family

ID=7710600

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0215337-8A BR0215337A (pt) 2001-12-21 2002-12-18 Piperidina-2, 6-dionas heretociclicamente substituìda na 3-posição

Country Status (27)

Country Link
US (1) US7183274B2 (pt)
EP (1) EP1456197B1 (pt)
JP (1) JP2005516953A (pt)
KR (1) KR20040068325A (pt)
CN (1) CN1620448A (pt)
AR (1) AR037963A1 (pt)
AT (1) ATE355285T1 (pt)
AU (1) AU2002364286A1 (pt)
BR (1) BR0215337A (pt)
CA (1) CA2471079A1 (pt)
CY (1) CY1106540T1 (pt)
DE (2) DE10163595A1 (pt)
DK (1) DK1456197T3 (pt)
EC (1) ECSP045161A (pt)
ES (1) ES2282514T3 (pt)
HU (1) HUP0402477A2 (pt)
IL (1) IL162619A0 (pt)
MX (1) MXPA04006120A (pt)
NO (1) NO20042946L (pt)
NZ (1) NZ533995A (pt)
PE (1) PE20030745A1 (pt)
PL (1) PL371028A1 (pt)
PT (1) PT1456197E (pt)
RU (1) RU2004122633A (pt)
SI (1) SI1456197T1 (pt)
WO (1) WO2003053956A1 (pt)
ZA (1) ZA200405780B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004026703A1 (de) * 2004-05-28 2005-12-29 Grünenthal GmbH Verfahren zur Herstellung von in 3-Position heterocyclisch substituierten Piperidin-2,6-dionen
DE102005057912A1 (de) 2005-12-02 2007-07-19 Grünenthal GmbH In 3-Position heterocyclisch substituierte Pyrrolidin(thi)one
KR200484781Y1 (ko) 2017-07-04 2017-10-25 김정래 지퍼손잡이 보호장치

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69330959T2 (de) * 1992-07-29 2002-04-11 Merck Sharp & Dohme Ltd., Hoddesdon Benzodiazepinderivate
WO1995002405A1 (en) * 1993-07-16 1995-01-26 Merck & Co., Inc. Benzoxazinone and benzopyrimidinone piperidinyl tocolytic oxytocin receptor antagonists
DE19843793C2 (de) * 1998-09-24 2000-08-03 Gruenenthal Gmbh Substituierte Benzamide
AU5448300A (en) 1999-05-27 2000-12-18 Rockefeller University, The Methods of promoting or enhancing interleukin-12 production through administration of thalidomide
US6767926B1 (en) * 1999-10-12 2004-07-27 Temple University - Of The Commonwealth System Of Higher Education Method for protecting normal cells from cytotoxicity of chemotherapeutic agents
DE19957342A1 (de) 1999-11-29 2001-05-31 Gruenenthal Gmbh Verfahren zur Behandlung und/oder Prophylaxe von IL-12-bedingten Erkrankungen
DE10002509A1 (de) * 2000-01-21 2001-07-26 Gruenenthal Gmbh Substituierte Glutarimide
DE10250082A1 (de) * 2002-10-25 2004-05-13 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel

Also Published As

Publication number Publication date
AR037963A1 (es) 2004-12-22
MXPA04006120A (es) 2004-11-01
AU2002364286A1 (en) 2003-07-09
US20050020581A1 (en) 2005-01-27
EP1456197A1 (de) 2004-09-15
CA2471079A1 (en) 2003-07-03
CN1620448A (zh) 2005-05-25
ES2282514T3 (es) 2007-10-16
NO20042946L (no) 2004-09-20
DK1456197T3 (da) 2007-06-11
US7183274B2 (en) 2007-02-27
HUP0402477A2 (hu) 2005-05-30
JP2005516953A (ja) 2005-06-09
RU2004122633A (ru) 2005-06-10
PL371028A1 (en) 2005-06-13
IL162619A0 (en) 2005-11-20
KR20040068325A (ko) 2004-07-30
PE20030745A1 (es) 2003-09-05
SI1456197T1 (sl) 2007-08-31
PT1456197E (pt) 2007-03-30
DE50209613D1 (de) 2007-04-12
WO2003053956A1 (de) 2003-07-03
NZ533995A (en) 2006-11-30
DE10163595A1 (de) 2003-08-07
ZA200405780B (en) 2005-07-26
EP1456197B1 (de) 2007-02-28
CY1106540T1 (el) 2012-01-25
ATE355285T1 (de) 2006-03-15
ECSP045161A (es) 2004-08-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 6A., 7A. E 8A. ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011.