ECSP045161A - Piperidin-2,6-diona sustituida con heterociclo en la posición 3 - Google Patents

Piperidin-2,6-diona sustituida con heterociclo en la posición 3

Info

Publication number
ECSP045161A
ECSP045161A EC2004005161A ECSP045161A ECSP045161A EC SP045161 A ECSP045161 A EC SP045161A EC 2004005161 A EC2004005161 A EC 2004005161A EC SP045161 A ECSP045161 A EC SP045161A EC SP045161 A ECSP045161 A EC SP045161A
Authority
EC
Ecuador
Prior art keywords
piperidin
heterocycle
dione substituted
substituted
dione
Prior art date
Application number
EC2004005161A
Other languages
English (en)
Inventor
Helmut Bushmann
Stefanie Frosch
Tieno Germann
Oswald Karl Zimmer
Fritz Theil
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of ECSP045161A publication Critical patent/ECSP045161A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se describen las piperidin-2,6-dionas sustituidas con heterociclo en la posición 3, su preparación y su empleo en medicamentos, en especial como inmunomoderadores para el tratamiento y/o la profilaxis de enfermedades inflamatorias y autoinmunológicas, así como enfermedades hematológico-oncológicas.
EC2004005161A 2001-12-21 2004-06-17 Piperidin-2,6-diona sustituida con heterociclo en la posición 3 ECSP045161A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10163595A DE10163595A1 (de) 2001-12-21 2001-12-21 In 3-Position heterocyclisch substituierte Piperidin-2,6-dione

Publications (1)

Publication Number Publication Date
ECSP045161A true ECSP045161A (es) 2004-08-27

Family

ID=7710600

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2004005161A ECSP045161A (es) 2001-12-21 2004-06-17 Piperidin-2,6-diona sustituida con heterociclo en la posición 3

Country Status (27)

Country Link
US (1) US7183274B2 (es)
EP (1) EP1456197B1 (es)
JP (1) JP2005516953A (es)
KR (1) KR20040068325A (es)
CN (1) CN1620448A (es)
AR (1) AR037963A1 (es)
AT (1) ATE355285T1 (es)
AU (1) AU2002364286A1 (es)
BR (1) BR0215337A (es)
CA (1) CA2471079A1 (es)
CY (1) CY1106540T1 (es)
DE (2) DE10163595A1 (es)
DK (1) DK1456197T3 (es)
EC (1) ECSP045161A (es)
ES (1) ES2282514T3 (es)
HU (1) HUP0402477A2 (es)
IL (1) IL162619A0 (es)
MX (1) MXPA04006120A (es)
NO (1) NO20042946L (es)
NZ (1) NZ533995A (es)
PE (1) PE20030745A1 (es)
PL (1) PL371028A1 (es)
PT (1) PT1456197E (es)
RU (1) RU2004122633A (es)
SI (1) SI1456197T1 (es)
WO (1) WO2003053956A1 (es)
ZA (1) ZA200405780B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004026703A1 (de) * 2004-05-28 2005-12-29 Grünenthal GmbH Verfahren zur Herstellung von in 3-Position heterocyclisch substituierten Piperidin-2,6-dionen
DE102005057912A1 (de) 2005-12-02 2007-07-19 Grünenthal GmbH In 3-Position heterocyclisch substituierte Pyrrolidin(thi)one
KR200484781Y1 (ko) 2017-07-04 2017-10-25 김정래 지퍼손잡이 보호장치

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003437A1 (en) * 1992-07-29 1994-02-17 Merck Sharp & Dohme Limited Benzodiazepine derivatives
WO1995002405A1 (en) * 1993-07-16 1995-01-26 Merck & Co., Inc. Benzoxazinone and benzopyrimidinone piperidinyl tocolytic oxytocin receptor antagonists
DE19843793C2 (de) * 1998-09-24 2000-08-03 Gruenenthal Gmbh Substituierte Benzamide
WO2000072836A2 (en) 1999-05-27 2000-12-07 The Rockefeller University Methods of promoting or enhancing interleukin-12 production through administration of thalidomide
US6767926B1 (en) 1999-10-12 2004-07-27 Temple University - Of The Commonwealth System Of Higher Education Method for protecting normal cells from cytotoxicity of chemotherapeutic agents
DE19957342A1 (de) 1999-11-29 2001-05-31 Gruenenthal Gmbh Verfahren zur Behandlung und/oder Prophylaxe von IL-12-bedingten Erkrankungen
DE10002509A1 (de) * 2000-01-21 2001-07-26 Gruenenthal Gmbh Substituierte Glutarimide
DE10250082A1 (de) * 2002-10-25 2004-05-13 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel

Also Published As

Publication number Publication date
BR0215337A (pt) 2004-11-16
EP1456197B1 (de) 2007-02-28
DK1456197T3 (da) 2007-06-11
DE50209613D1 (de) 2007-04-12
PL371028A1 (en) 2005-06-13
PE20030745A1 (es) 2003-09-05
EP1456197A1 (de) 2004-09-15
AU2002364286A1 (en) 2003-07-09
DE10163595A1 (de) 2003-08-07
SI1456197T1 (sl) 2007-08-31
RU2004122633A (ru) 2005-06-10
JP2005516953A (ja) 2005-06-09
MXPA04006120A (es) 2004-11-01
ES2282514T3 (es) 2007-10-16
CN1620448A (zh) 2005-05-25
US7183274B2 (en) 2007-02-27
NO20042946L (no) 2004-09-20
AR037963A1 (es) 2004-12-22
NZ533995A (en) 2006-11-30
CA2471079A1 (en) 2003-07-03
PT1456197E (pt) 2007-03-30
IL162619A0 (en) 2005-11-20
WO2003053956A1 (de) 2003-07-03
CY1106540T1 (el) 2012-01-25
US20050020581A1 (en) 2005-01-27
KR20040068325A (ko) 2004-07-30
HUP0402477A2 (hu) 2005-05-30
ZA200405780B (en) 2005-07-26
ATE355285T1 (de) 2006-03-15

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