BR0214481A - Método e composição para potenciação de um analgésico opiáceo - Google Patents

Método e composição para potenciação de um analgésico opiáceo

Info

Publication number
BR0214481A
BR0214481A BR0214481-6A BR0214481A BR0214481A BR 0214481 A BR0214481 A BR 0214481A BR 0214481 A BR0214481 A BR 0214481A BR 0214481 A BR0214481 A BR 0214481A
Authority
BR
Brazil
Prior art keywords
composition
opioid analgesic
potentiation
analgesic
potentialing
Prior art date
Application number
BR0214481-6A
Other languages
English (en)
Inventor
Anil Gulati
Original Assignee
Univ Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois filed Critical Univ Illinois
Publication of BR0214481A publication Critical patent/BR0214481A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"MéTODO E COMPOSIçãO PARA POTENCIAçãO DE UM ANALGéSICO OPIáCEO". Composição e método de tratamento da dor e redução ou reversão de tolerância a um analgésico opiáceo é revelado. A composição e o método utilizam um analgésico opiáceo e um antagonista de endotelina como agente ativo para tratar a dor em mamíferos, incluindo os humanos.
BR0214481-6A 2001-11-27 2002-11-22 Método e composição para potenciação de um analgésico opiáceo BR0214481A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33359901P 2001-11-27 2001-11-27
PCT/US2002/037461 WO2003045434A2 (en) 2001-11-27 2002-11-22 Endothelin antagonists ina method and composition for potentiating an opiate analgesic

Publications (1)

Publication Number Publication Date
BR0214481A true BR0214481A (pt) 2004-09-14

Family

ID=23303472

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214481-6A BR0214481A (pt) 2001-11-27 2002-11-22 Método e composição para potenciação de um analgésico opiáceo

Country Status (14)

Country Link
US (3) US7973064B2 (pt)
EP (1) EP1448233A2 (pt)
JP (1) JP2005513033A (pt)
CN (1) CN1646166A (pt)
AU (1) AU2002348224A1 (pt)
BR (1) BR0214481A (pt)
CA (1) CA2464768C (pt)
CO (1) CO5590940A2 (pt)
EA (1) EA200400734A1 (pt)
EC (1) ECSP045153A (pt)
MX (1) MXPA04005003A (pt)
NO (1) NO20042612L (pt)
WO (1) WO2003045434A2 (pt)
ZA (1) ZA200403162B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
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US20070300258A1 (en) * 2001-01-29 2007-12-27 O'connor Daniel Methods and systems for providing media assets over a network
EP1395289B1 (en) * 2001-06-07 2010-12-15 Christine Dr. Sang Treatment of neuropathic pain with a n-methyl-d-aspartate (nmda) receptor antagonists
TWI232102B (en) * 2001-07-17 2005-05-11 Shionogi & Co A pharmaceutical formulation for injection
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
ES2341922T3 (es) 2001-11-01 2010-06-29 Spectrum Pharmaceuticals, Inc. Composiciones medicas para el tratamiento intravesical de cancer de vejiga.
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
US7351692B2 (en) 2002-06-19 2008-04-01 The Board Of Trustees Of The University Of Illinois Method and composition for potentiating the antipyretic action of a nonopioid analgesic
GB0219660D0 (en) 2002-08-23 2002-10-02 Astrazeneca Ab Therapeutic use
AU2003286647B2 (en) 2002-10-24 2009-11-05 The Board Of Trustees Of The University Of Illinois Method and composition for preventing and treating solid tumors
US8026216B2 (en) 2002-10-24 2011-09-27 Spectrum Pharmaceuticals, Inc. Methods and compositions for contributing to the treatment of cancers
US8217010B2 (en) 2002-10-24 2012-07-10 The Board Of Trustees Of The University Of Illinois Methods, compositions and articles of manufacture for contributing to the treatment of solid tumors
US20070032422A1 (en) 2002-10-24 2007-02-08 Spectrum Pharmaceuticals, Inc. Methods, compositions and articles of manufacture for contributing to the treatment of cancers
GB0403744D0 (en) 2004-02-20 2004-03-24 Astrazeneca Ab Chemical process
CA2641386A1 (en) * 2005-09-09 2007-03-15 Chicago Labs, Inc. Endothelin receptors in morphine withdrawal
US20070112017A1 (en) * 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
KR101547361B1 (ko) 2006-08-31 2015-08-25 스펙트럼 파마슈티컬즈 인크 엔도셀린 효능제 투여를 통한 방사선 요법에 대한 종양 세포의 감작
GB0624880D0 (en) * 2006-12-14 2007-01-24 Johnson Matthey Plc Improved method for making analgesics
WO2009015917A2 (en) * 2007-05-14 2009-02-05 F. Hoffmann-La Roche Ag Dihydroquinone and dihydronaphthridine inhibitors of jnk
US20090143426A1 (en) * 2007-12-04 2009-06-04 Ralph Anthony Stephani Synthesis of 1,3,6-trisubstituted-2-carboxyquinol-4-ones as selective ET A antagonists and their use as medicaments
JP5498571B2 (ja) * 2009-04-30 2014-05-21 ミッドウェスタン ユニバーシティ センタキンを用いた新規の治療方法
US9308235B2 (en) 2012-05-09 2016-04-12 Spectrum Pharmaceuticals, Inc. Treatment of primary and metastatic carcinoma
JP6928450B2 (ja) 2013-07-08 2021-09-01 ミッドウェスタン ユニバーシティ エンドセリンｂ受容体アゴニストを用いた、神経精神疾患を治療するための組成物及び方法
CN112569238A (zh) * 2019-09-30 2021-03-30 武汉大学 伊马替尼及其衍生物与镇痛药联合用药或复方制剂在治疗疼痛中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612359A (en) * 1994-08-26 1997-03-18 Bristol-Myers Squibb Company Substituted biphenyl isoxazole sulfonamides
JPH08139146A (ja) * 1994-11-14 1996-05-31 Shin Etsu Handotai Co Ltd 半導体表面のライフタイム評価方法
EP1609477B1 (en) 1994-12-12 2011-11-09 Omeros Corporation Irrigation solution and use thereof for the perioperative inhibition of pain/inflammation and/or spasm at a vascular structure
US6673832B1 (en) * 1998-05-04 2004-01-06 Gudarz Davar Methods for identifying compounds for treating pain
CA2409927A1 (en) 2000-05-31 2001-12-06 Warner-Lambert Company Combinations of an endothelin receptor antagonist and an antiepileptic compound having pain alleviating properties or analgesic
WO2002049630A2 (en) * 2000-12-21 2002-06-27 Bristol-Myers Squibb Company Method for preventing or treating pain by administering an endothelin antagonist
US20030232787A1 (en) * 2001-05-08 2003-12-18 Dooley David James Combinations of an endothelin receptor antagonist and an antiepileptic compound having pain alleviating properties or analgesic

Also Published As

Publication number Publication date
EP1448233A2 (en) 2004-08-25
ECSP045153A (es) 2004-08-27
CA2464768C (en) 2009-12-29
WO2003045434A2 (en) 2003-06-05
US20100113396A1 (en) 2010-05-06
US7973064B2 (en) 2011-07-05
JP2005513033A (ja) 2005-05-12
AU2002348224A1 (en) 2003-06-10
EA200400734A1 (ru) 2004-12-30
US8114896B2 (en) 2012-02-14
NO20042612L (no) 2004-06-22
MXPA04005003A (es) 2004-08-11
ZA200403162B (en) 2005-01-26
CA2464768A1 (en) 2003-06-05
US8410148B2 (en) 2013-04-02
CN1646166A (zh) 2005-07-27
US20100311665A1 (en) 2010-12-09
US20030100507A1 (en) 2003-05-29
WO2003045434A3 (en) 2003-09-25
CO5590940A2 (es) 2005-12-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 4A, 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2034 DE 29/12/2009.