BR0213734A - Heteroaromatic carboxamide derivatives for the treatment of inflammation - Google Patents

Heteroaromatic carboxamide derivatives for the treatment of inflammation

Info

Publication number
BR0213734A
BR0213734A BR0213734-8A BR0213734A BR0213734A BR 0213734 A BR0213734 A BR 0213734A BR 0213734 A BR0213734 A BR 0213734A BR 0213734 A BR0213734 A BR 0213734A
Authority
BR
Brazil
Prior art keywords
inflammation
carboxamide derivatives
treatment
heteroaromatic carboxamide
heteroaromatic
Prior art date
Application number
BR0213734-8A
Other languages
Portuguese (pt)
Inventor
Matthew Graneto
Cathleen E Hanau
Thao D Perry
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of BR0213734A publication Critical patent/BR0213734A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

"DERIVADOS DE CARBOXAMIDA HETEROAROMáTICO PARA O TRATAMENTO DE INFLAMAçãO". A presente invenção refere-se a derivados de carboxamida heteroaromático, composições compreendendo os mesmos, intermediários, métodos de fabricar derivados de carboxamida heteroaromático e métodos para tratamento de câncer, inflamação e distúrbios associados à inflamação como artrite."Heteroaryomatic Carboxamide Derivatives for the Treatment of Inflammation". The present invention relates to heteroaromatic carboxamide derivatives, compositions comprising them, intermediates, methods of manufacturing heteroaromatic carboxamide derivatives and methods for treating cancer, inflammation and inflammation-associated disorders such as arthritis.

BR0213734-8A 2001-10-30 2002-10-30 Heteroaromatic carboxamide derivatives for the treatment of inflammation BR0213734A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34081601P 2001-10-30 2001-10-30
PCT/US2002/034801 WO2003037886A2 (en) 2001-10-30 2002-10-30 Heteroaromatic carboxamide derivatives for the treatment of inflammation

Publications (1)

Publication Number Publication Date
BR0213734A true BR0213734A (en) 2004-10-19

Family

ID=23335051

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0213734-8A BR0213734A (en) 2001-10-30 2002-10-30 Heteroaromatic carboxamide derivatives for the treatment of inflammation

Country Status (7)

Country Link
EP (1) EP1444010A2 (en)
JP (1) JP2005509645A (en)
AU (1) AU2002356871A1 (en)
BR (1) BR0213734A (en)
CA (1) CA2464924A1 (en)
MX (1) MXPA04004064A (en)
WO (1) WO2003037886A2 (en)

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JP5546240B2 (en) 2006-04-26 2014-07-09 ジェネンテック， インコーポレイテッド Pharmaceutical compounds
US8853244B2 (en) 2006-05-23 2014-10-07 Vertex Pharmaceuticals Incorporated Thiophene-carboxamides useful as inhibitors of protein kinases
US7851495B2 (en) 2006-05-23 2010-12-14 Vertex Pharmaceuticals Incorporated Thiophene-carboxamides useful as inhibitors of protein kinases
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MY180595A (en) 2006-12-07 2020-12-03 Genentech Inc Phosphoinositide 3-kinase inhibitor compounds and methods of use
PE20081889A1 (en) 2007-03-23 2009-03-05 Smithkline Beecham Corp INDOL CARBOXAMIDES AS INHIBITORS OF IKK2
EP2207781B1 (en) 2007-09-24 2012-11-28 Genentech, Inc. Thiazolopyrimidine p13k inhibitor compounds and methods of use
PE20131210A1 (en) 2007-12-19 2013-10-31 Genentech Inc 5-ANILINOIMIDAZOPYRIDINE DERIVATIVES AS MEK INHIBITORS
WO2009082687A1 (en) 2007-12-21 2009-07-02 Genentech, Inc. Azaindolizines and methods of use
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JP2012520257A (en) 2009-03-10 2012-09-06 グラクソ グループ リミテッド Indole derivatives as IKK2 inhibitors
WO2010105008A2 (en) 2009-03-12 2010-09-16 Genentech, Inc. Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
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JP5546636B2 (en) 2009-09-28 2014-07-09 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Benzoxepin PI3K inhibitor compounds and methods of use
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PL2675479T3 (en) 2011-02-15 2016-09-30 Cytotoxic benzodiazepine derivatives
EA024842B9 (en) 2011-05-04 2017-08-31 Ризен Фармасьютикалз Са Compounds as modulators of pi3k protein kinase
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Also Published As

Publication number Publication date
WO2003037886A2 (en) 2003-05-08
AU2002356871A1 (en) 2003-05-12
WO2003037886A3 (en) 2003-12-24
JP2005509645A (en) 2005-04-14
EP1444010A2 (en) 2004-08-11
CA2464924A1 (en) 2003-05-08
MXPA04004064A (en) 2004-09-06

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 5O, 6O E 7O ANUIDADE.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2034 DE 29/12/2009.

B15K Others concerning applications: alteration of classification

Ipc: C07D 333/38 (2006.01), A61P 29/00 (2006.01), C07D