BR0211264A - Ligação paralela ou antiparalela, homóloga ou complementar, de ácidos nucleicos ou análogos dos mesmos para formar complexos duplex, triplex ou quadruplex - Google Patents
Ligação paralela ou antiparalela, homóloga ou complementar, de ácidos nucleicos ou análogos dos mesmos para formar complexos duplex, triplex ou quadruplexInfo
- Publication number
- BR0211264A BR0211264A BR0211264-7A BR0211264A BR0211264A BR 0211264 A BR0211264 A BR 0211264A BR 0211264 A BR0211264 A BR 0211264A BR 0211264 A BR0211264 A BR 0211264A
- Authority
- BR
- Brazil
- Prior art keywords
- heteropolymer
- target
- triplex
- analogs
- sequence
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/125—Specific component of sample, medium or buffer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/119—Triple helix formation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/137—Metal/ion, e.g. metal label
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/173—Nucleic acid detection characterized by the use of physical, structural and functional properties staining/intercalating agent, e.g. ethidium bromide
Abstract
"LIGAçãO PARALELA OU ANTIPARALELA, HOMóLOGA OU COMPLEMENTAR, DE áCIDOS NUCLEICOS OU ANáLOGOS DOS MESMOS PARA FORMAR COMPLEXOS DUPLEX, TRIPLEX OU QUADRUPLEX". Um complexo inclui (1) uma sonda contendo uma seq³ência de sonda heteropolimórica de ácidos nucléicos ou análogos de ácidos nucléicos; e, (2) um alvo contendo uma seq³ência alvo heteropolimérica de ácidos nucléicos ou análogos de ácidos nucléicos, onde: (a) ao menos a dita sonda ou dito alvo é purificado ou sintético; e, (b) dita seq³ência de sonda heteropolimérica está ligada à dita seq³ência alvo heteropolimérica pela interação de base complementar de Watson-Crick ou por interação de base homóloga, desde que quando o dito complexo é um duplex a dita seq³ência de sonda heteropolimérica é antiparalela à dita seq³ência alvo heteropolimérica, dita seq³ência de sonda heteropolimérica está ligada à dita seq³ência alvo heteropolimórica por interação de base homóloga, e desde que quando o dito complexo é um triplex, o dito complexo está livre de proteínas recombinantes. Método para ensaiar um alvo inclui detectar a formação do complexo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/909,496 US6656692B2 (en) | 1999-12-21 | 2001-07-20 | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
PCT/IB2002/002791 WO2003010326A2 (en) | 2001-07-20 | 2002-07-15 | Parallel, antiparallel, homologous or complementary binding of nucleic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0211264A true BR0211264A (pt) | 2005-03-29 |
Family
ID=25427322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0211264-7A BR0211264A (pt) | 2001-07-20 | 2002-07-15 | Ligação paralela ou antiparalela, homóloga ou complementar, de ácidos nucleicos ou análogos dos mesmos para formar complexos duplex, triplex ou quadruplex |
Country Status (15)
Country | Link |
---|---|
US (1) | US6656692B2 (pt) |
EP (1) | EP1463831A4 (pt) |
JP (1) | JP2005527181A (pt) |
KR (1) | KR100699367B1 (pt) |
CN (1) | CN100560733C (pt) |
AU (1) | AU2002345301B2 (pt) |
BR (1) | BR0211264A (pt) |
CA (1) | CA2454300C (pt) |
CO (1) | CO5560626A2 (pt) |
IL (1) | IL159927A0 (pt) |
MX (1) | MXPA04000626A (pt) |
NZ (1) | NZ531258A (pt) |
RU (1) | RU2304169C2 (pt) |
WO (1) | WO2003010326A2 (pt) |
ZA (1) | ZA200401362B (pt) |
Families Citing this family (17)
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US6927027B2 (en) * | 1999-12-21 | 2005-08-09 | Ingeneus Corporation | Nucleic acid multiplex formation |
US7052844B2 (en) * | 1999-12-21 | 2006-05-30 | Ingeneus, Inc. | Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism |
US7220541B2 (en) * | 2000-01-24 | 2007-05-22 | Ingeneus, Inc. | Homogeneous assay of biopolymer binding by means of multiple measurements under varied conditions |
MXPA05002883A (es) * | 2002-08-20 | 2005-10-05 | Protemix Corp Ltd | Formas de dosis y terapias relacionadas. |
US20040142329A1 (en) * | 2003-01-17 | 2004-07-22 | Ingeneus Corporation | Probe conjugation to increase multiplex binding motif preference |
US20040180345A1 (en) * | 2003-03-14 | 2004-09-16 | Ingeneus Corporation | Pre-incubation method to improve signal/noise ratio of nucleic acid assays |
GB0310270D0 (en) * | 2003-05-03 | 2003-06-11 | Univ Edinburgh | Biomolecular devices |
WO2005067437A2 (en) * | 2003-08-06 | 2005-07-28 | Cygene, Inc. | Methods and compositions for in vitro and in vivo use of parallel stranded hairpins and triplex structures as nucleic acid ligands |
JP2008514197A (ja) * | 2004-09-24 | 2008-05-08 | インジェネウス インコーポレイテッド | ゲノムアッセイ |
WO2006124089A1 (en) * | 2005-05-12 | 2006-11-23 | The Arizona Board Of Regents, A Body Corporate Acting On Behalf Of Arizona State University | Self-assembled nucleic acid nanoarrays and uses therefor |
KR100833492B1 (ko) * | 2005-12-08 | 2008-05-29 | 한국전자통신연구원 | 핵산 나노구조체 및 그의 제조 방법 |
WO2010026450A1 (en) * | 2008-09-03 | 2010-03-11 | Quantumdx Group Limited | Sensing strategies and methods for nucleic acid detection using biosensors |
WO2012096430A1 (en) * | 2011-01-11 | 2012-07-19 | Seegene, Inc. | Detection of target nucleic acid sequences by pto cleavage and extension assay |
KR102078892B1 (ko) * | 2012-02-09 | 2020-02-19 | 라이프 테크놀로지스 코포레이션 | 접합된 중합체성 입자 및 그의 제조 방법 |
WO2016057597A1 (en) * | 2014-10-09 | 2016-04-14 | Albert Einstein College Of Medicine, Inc. | Programmed cargo release using nucleic acid-stabilized micelles |
CN108047135B (zh) * | 2017-12-29 | 2019-12-17 | 苏州宇恒生物科技有限公司 | 一种荧光染料及其制备方法与在细菌检测中的应用 |
CN113971015B (zh) * | 2021-11-10 | 2023-09-08 | 哲库科技(北京)有限公司 | Uia2计算电路及其数据处理方法、芯片、电子设备及存储介质 |
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-
2001
- 2001-07-20 US US09/909,496 patent/US6656692B2/en not_active Expired - Lifetime
-
2002
- 2002-07-15 EP EP02743548A patent/EP1463831A4/en not_active Withdrawn
- 2002-07-15 KR KR1020047001025A patent/KR100699367B1/ko not_active IP Right Cessation
- 2002-07-15 RU RU2004105040/13A patent/RU2304169C2/ru not_active IP Right Cessation
- 2002-07-15 WO PCT/IB2002/002791 patent/WO2003010326A2/en active Application Filing
- 2002-07-15 CA CA2454300A patent/CA2454300C/en not_active Expired - Fee Related
- 2002-07-15 JP JP2003515676A patent/JP2005527181A/ja active Pending
- 2002-07-15 CN CNB028146891A patent/CN100560733C/zh not_active Expired - Fee Related
- 2002-07-15 AU AU2002345301A patent/AU2002345301B2/en not_active Ceased
- 2002-07-15 NZ NZ531258A patent/NZ531258A/en unknown
- 2002-07-15 MX MXPA04000626A patent/MXPA04000626A/es active IP Right Grant
- 2002-07-15 IL IL15992702A patent/IL159927A0/xx unknown
- 2002-07-15 BR BR0211264-7A patent/BR0211264A/pt not_active IP Right Cessation
-
2004
- 2004-02-19 ZA ZA200401362A patent/ZA200401362B/en unknown
- 2004-02-20 CO CO04015135A patent/CO5560626A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200401362B (en) | 2005-05-27 |
MXPA04000626A (es) | 2004-07-08 |
IL159927A0 (en) | 2004-06-20 |
RU2004105040A (ru) | 2005-05-27 |
WO2003010326A2 (en) | 2003-02-06 |
WO2003010326A3 (en) | 2004-07-22 |
CN1650026A (zh) | 2005-08-03 |
CO5560626A2 (es) | 2005-09-30 |
EP1463831A4 (en) | 2005-03-23 |
CA2454300C (en) | 2013-11-19 |
US20020031775A1 (en) | 2002-03-14 |
CN100560733C (zh) | 2009-11-18 |
RU2304169C2 (ru) | 2007-08-10 |
JP2005527181A (ja) | 2005-09-15 |
CA2454300A1 (en) | 2003-02-06 |
KR20040023671A (ko) | 2004-03-18 |
AU2002345301B2 (en) | 2006-08-24 |
NZ531258A (en) | 2008-04-30 |
KR100699367B1 (ko) | 2007-03-27 |
US6656692B2 (en) | 2003-12-02 |
EP1463831A2 (en) | 2004-10-06 |
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