BR0210602A - Implante osmótico com membrana e recurso de retenção da membrana - Google Patents
Implante osmótico com membrana e recurso de retenção da membranaInfo
- Publication number
- BR0210602A BR0210602A BR0210602-7A BR0210602A BR0210602A BR 0210602 A BR0210602 A BR 0210602A BR 0210602 A BR0210602 A BR 0210602A BR 0210602 A BR0210602 A BR 0210602A
- Authority
- BR
- Brazil
- Prior art keywords
- membrane
- capsule
- osmotic
- membrane material
- retention feature
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title abstract 9
- 230000003204 osmotic effect Effects 0.000 title abstract 6
- 230000014759 maintenance of location Effects 0.000 title abstract 3
- 239000007943 implant Substances 0.000 title abstract 2
- 239000002775 capsule Substances 0.000 abstract 6
- 239000000463 material Substances 0.000 abstract 5
- 230000009286 beneficial effect Effects 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000012530 fluid Substances 0.000 abstract 2
- 238000003490 calendering Methods 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 238000003754 machining Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- External Artificial Organs (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Prostheses (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Abstract
"IMPLANTE OSMóTICO COM MEMBRANA E RECURSO DE RETENçãO DA MEMBRANA". Um sistema de liberação osmótico para a liberação controlada de um agente benéfico inclui uma cápsula que pode ser implantada contendo um agente benéfico e um mecanismo osmótico que dilata no contato com água, para dessa maneira causar a liberação do agente benéfico com o tempo. O sistema de liberação osmótico tem um material de membrana que permite que uma quantidade controlada de fluido entre do exterior da cápsula, enquanto evitando que as composições dentro da cápsula saiam da cápsula. O sistema de liberação osmótico é projetado para alcançar pelo menos as pressões de operação de 6875 Kpa (1000 psi), o material da membrana é fundido, calandrado ou extrudado seguido pela usinagem (isto é, corte em matriz, estampagem ou de outra maneira corte na forma) para produzir um material de membrana uniforme sem nervuras. A cápsula também inclui um recurso de retenção do material de membrana que é posicionado em uma extremidade de absorção do fluido para manter o material da membrana dentro da cápsula, mesmo sob períodos de alta pressão.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30057501P | 2001-06-22 | 2001-06-22 | |
PCT/US2002/019531 WO2003000230A1 (en) | 2001-06-22 | 2002-06-21 | Osmotic implant with membrane and membrane retention means |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0210602A true BR0210602A (pt) | 2004-09-28 |
Family
ID=23159679
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0210602-7A BR0210602A (pt) | 2001-06-22 | 2002-06-21 | Implante osmótico com membrana e recurso de retenção da membrana |
Country Status (19)
Country | Link |
---|---|
US (2) | US7163688B2 (pt) |
EP (1) | EP1401395B1 (pt) |
JP (1) | JP2004536640A (pt) |
CN (1) | CN1547463A (pt) |
AT (1) | ATE293436T1 (pt) |
AU (1) | AU2002315374B2 (pt) |
BR (1) | BR0210602A (pt) |
CA (1) | CA2451327C (pt) |
DE (1) | DE60203800T2 (pt) |
ES (1) | ES2243738T3 (pt) |
HU (1) | HUP0400334A3 (pt) |
IL (2) | IL159374A0 (pt) |
MX (1) | MXPA04000019A (pt) |
NO (1) | NO20035653L (pt) |
NZ (1) | NZ530260A (pt) |
PL (1) | PL364459A1 (pt) |
RU (1) | RU2295359C2 (pt) |
WO (1) | WO2003000230A1 (pt) |
ZA (1) | ZA200400453B (pt) |
Families Citing this family (49)
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MY125870A (en) * | 1997-07-25 | 2006-08-30 | Alza Corp | Osmotic delivery system flow modulator apparatus and method |
US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
CA2489325C (en) * | 2002-06-17 | 2010-08-10 | Alza Corporation | Osmotic delivery system with early zero order push power engine comprising an osmotic agent dispersed in the fluid vehicle |
JP2006512370A (ja) * | 2002-12-19 | 2006-04-13 | アルザ・コーポレーション | 安定な非水性単相ゲル、および植込み型デバイスから送達するためのその配合物 |
US7731947B2 (en) * | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
JP2006521897A (ja) * | 2003-03-31 | 2006-09-28 | アルザ・コーポレーション | 内部圧力を放散する手段を備える浸透ポンプ |
MXPA05010604A (es) * | 2003-03-31 | 2005-11-23 | Alza Corp | Sistema de administracion osmotica y metodo para disminuir los tiempos de arranque para sistemas de administracion osmotica. |
EP1667652B1 (en) * | 2003-09-26 | 2007-05-30 | ALZA Corporation | Improved controlled release dosage form including a banded engine |
SE526959C2 (sv) * | 2003-10-02 | 2005-11-29 | Tikomed Ab | Bioartificellt implantat innefattande en semipermeabel barriär samt förfarande för reducering av risken för bildning av bindrväv vid implantatet efter implantering genom att barriären förses med en permeabel beläggning av bioaktiv metall |
RU2006119632A (ru) * | 2003-11-06 | 2007-12-20 | Алза Корпорейшн (Us) | Модульный ограничитель скорости впитывания для использования с имплантируемым осмотическим насосом |
US20050266087A1 (en) * | 2004-05-25 | 2005-12-01 | Gunjan Junnarkar | Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
EP2361630A1 (en) * | 2005-02-03 | 2011-08-31 | Intarcia Therapeutics, Inc | Implantable drug delivery device comprising particles and an osmotic pump |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US7959938B2 (en) * | 2005-03-15 | 2011-06-14 | Intarcia Therapeutics, Inc. | Polyoxaester suspending vehicles for use with implantable delivery systems |
US20080312587A1 (en) * | 2005-06-10 | 2008-12-18 | Gruenethal Gmbh | System for the Oral Administration of Solids to Persons Suffering from Dementia |
KR101106510B1 (ko) | 2006-05-30 | 2012-01-20 | 인타르시아 세라퓨틱스 인코포레이티드 | 투피스, 내부채널 삼투압 전달 시스템 유동 조절기 |
WO2008079440A2 (en) | 2006-07-10 | 2008-07-03 | Medipacs, Inc. | Super elastic epoxy hydrogel |
AU2007284759B2 (en) | 2006-08-09 | 2010-10-28 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
RU2440097C2 (ru) | 2007-04-23 | 2012-01-20 | Интарсия Терапьютикс, Инк. | Способ лечения диабета ii типа и ожирения, осмотическое устройство для доставки и способ его изготовления |
US20130079749A1 (en) * | 2007-08-29 | 2013-03-28 | Advanced Bionics, Llc | Modular Drug Delivery System for Minimizing Trauma During and After Insertion of a Cochlear Lead |
EP2227635A2 (en) | 2007-12-03 | 2010-09-15 | Medipacs, Inc. | Fluid metering device |
DK2240155T3 (da) | 2008-02-13 | 2012-09-17 | Intarcia Therapeutics Inc | Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler |
NZ592113A (en) * | 2008-10-15 | 2012-04-27 | Intarcia Therapeutics Inc | Highly concentrated drug particles, formulations, suspensions and uses thereof |
WO2010054296A2 (en) * | 2008-11-07 | 2010-05-14 | Combinent Biomedical Systems, Inc. | Devices and methods for treating and/or preventing diseases |
US9238102B2 (en) | 2009-09-10 | 2016-01-19 | Medipacs, Inc. | Low profile actuator and improved method of caregiver controlled administration of therapeutics |
EP3735944A1 (en) | 2009-09-28 | 2020-11-11 | Intarcia Therapeutics, Inc. | Rapid establishment and/or termination of substantial steady-state drug delivery |
US9500186B2 (en) | 2010-02-01 | 2016-11-22 | Medipacs, Inc. | High surface area polymer actuator with gas mitigating components |
US8820871B2 (en) | 2010-10-27 | 2014-09-02 | Matthews Resources, Inc. | Valve jet printer with inert plunger tip |
WO2012061556A1 (en) | 2010-11-03 | 2012-05-10 | Flugen, Inc. | Wearable drug delivery device having spring drive and sliding actuation mechanism |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
CN104302689A (zh) | 2012-03-14 | 2015-01-21 | 麦德医像公司 | 含有过量活性分子的智能聚合物材料 |
US20140147566A1 (en) * | 2012-11-28 | 2014-05-29 | Quirky, Inc. | Egg yolk separation apparatus and methods |
CN104001261A (zh) * | 2013-02-27 | 2014-08-27 | 重庆市北碚区精神卫生中心 | 一种皮下给药装置 |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
MA44390A (fr) | 2015-06-03 | 2019-01-23 | Intarcia Therapeutics Inc | Systèmes de mise en place et de retrait d'implant |
PL3370705T3 (pl) | 2015-11-05 | 2022-08-01 | The General Hospital Corporation | Dooponowe dostarczanie sekwencji kwasów nukleinowych do kodowania abcd1 w leczeniu adrenomieloneuropatii |
WO2017200943A1 (en) | 2016-05-16 | 2017-11-23 | Intarcia Therapeutics, Inc. | Glucagon-receptor selective polypeptides and methods of use thereof |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
MX2019004476A (es) | 2016-10-20 | 2019-09-23 | Peptron Inc | Metodos para administrar un polipeptido neuroprotector al sistema nervioso central. |
IL267736B2 (en) | 2017-01-03 | 2024-03-01 | Intarcia Therapeutics Inc | Methods involving continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
KR20190126335A (ko) | 2017-03-08 | 2019-11-11 | 인타르시아 세라퓨틱스 인코포레이티드 | 약물 전달 장치로부터 메스꺼움 유발 화합물을 투여하기 위한 장치 및 방법 |
CN107970522A (zh) * | 2017-11-24 | 2018-05-01 | 黑龙江工程学院 | 一种可降解金属基皮下载药埋置物及其制备方法 |
USD933219S1 (en) | 2018-07-13 | 2021-10-12 | Intarcia Therapeutics, Inc. | Implant removal tool and assembly |
WO2020077129A1 (en) | 2018-10-11 | 2020-04-16 | Intarcia Therapeutics, Inc. | Human amylin analog polypeptides and methods of use |
CN112618094B (zh) * | 2020-12-15 | 2021-12-10 | 上海澎立生技医药研究有限公司 | 一种脑梗的颈静脉插管给药装置 |
CN113749820B (zh) * | 2021-09-01 | 2024-10-01 | 上海竞捷医疗科技有限公司 | 用于关节组织的修复装置以及假体系统 |
Family Cites Families (23)
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US3732865A (en) * | 1971-01-13 | 1973-05-15 | Alza Corp | Osmotic dispenser |
US3987790A (en) | 1975-10-01 | 1976-10-26 | Alza Corporation | Osmotically driven fluid dispenser |
US4865845A (en) | 1986-03-21 | 1989-09-12 | Alza Corporation | Release rate adjustment of osmotic or diffusional delivery devices |
US5059423A (en) | 1988-12-13 | 1991-10-22 | Alza Corporation | Delivery system comprising biocompatible beneficial agent formulation |
US5112614A (en) | 1989-09-14 | 1992-05-12 | Alza Corporation | Implantable delivery dispenser |
US5213809A (en) | 1990-01-24 | 1993-05-25 | Alza Corporation | Delivery system comprising means for controlling internal pressure |
US5324280A (en) | 1990-04-02 | 1994-06-28 | Alza Corporation | Osmotic dosage system for delivering a formulation comprising liquid carrier and drug |
US5234693A (en) | 1990-07-11 | 1993-08-10 | Alza Corporation | Delivery device with a protective sleeve |
US5234692A (en) | 1990-07-11 | 1993-08-10 | Alza Corporation | Delivery device with a protective sleeve |
US5137727A (en) | 1991-06-12 | 1992-08-11 | Alza Corporation | Delivery device providing beneficial agent stability |
US5308348A (en) | 1992-02-18 | 1994-05-03 | Alza Corporation | Delivery devices with pulsatile effect |
US5324693A (en) * | 1992-10-13 | 1994-06-28 | Mitsubishi Materials Corporation | Ceramic composites and process for manufacturing the same |
US5540665A (en) | 1994-01-31 | 1996-07-30 | Alza Corporation | Gas driven dispensing device and gas generating engine therefor |
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AU1828599A (en) | 1997-12-29 | 1999-07-19 | Alza Corporation | Osmotic delivery system with membrane plug retention mechanism |
EP1041974B1 (en) * | 1997-12-30 | 2006-10-11 | Alza Corporation | Beneficial agent delivery system with membrane plug |
DE69906132T2 (de) * | 1998-12-31 | 2003-12-18 | Alza Corp., Mountain View | Osmotisches verabreichungsystem mit raumsparenden kolben |
CA2489325C (en) * | 2002-06-17 | 2010-08-10 | Alza Corporation | Osmotic delivery system with early zero order push power engine comprising an osmotic agent dispersed in the fluid vehicle |
US7014636B2 (en) * | 2002-11-21 | 2006-03-21 | Alza Corporation | Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel |
RU2006119632A (ru) * | 2003-11-06 | 2007-12-20 | Алза Корпорейшн (Us) | Модульный ограничитель скорости впитывания для использования с имплантируемым осмотическим насосом |
-
2002
- 2002-06-18 US US10/173,992 patent/US7163688B2/en not_active Expired - Lifetime
- 2002-06-21 JP JP2003506877A patent/JP2004536640A/ja active Pending
- 2002-06-21 RU RU2003136753/14A patent/RU2295359C2/ru not_active IP Right Cessation
- 2002-06-21 AT AT02742222T patent/ATE293436T1/de not_active IP Right Cessation
- 2002-06-21 WO PCT/US2002/019531 patent/WO2003000230A1/en active IP Right Grant
- 2002-06-21 NZ NZ530260A patent/NZ530260A/en not_active IP Right Cessation
- 2002-06-21 BR BR0210602-7A patent/BR0210602A/pt not_active IP Right Cessation
- 2002-06-21 EP EP02742222A patent/EP1401395B1/en not_active Expired - Lifetime
- 2002-06-21 DE DE60203800T patent/DE60203800T2/de not_active Expired - Lifetime
- 2002-06-21 IL IL15937402A patent/IL159374A0/xx active IP Right Grant
- 2002-06-21 PL PL02364459A patent/PL364459A1/xx not_active Application Discontinuation
- 2002-06-21 ES ES02742222T patent/ES2243738T3/es not_active Expired - Lifetime
- 2002-06-21 HU HU0400334A patent/HUP0400334A3/hu unknown
- 2002-06-21 CA CA2451327A patent/CA2451327C/en not_active Expired - Lifetime
- 2002-06-21 AU AU2002315374A patent/AU2002315374B2/en not_active Ceased
- 2002-06-21 MX MXPA04000019A patent/MXPA04000019A/es active IP Right Grant
- 2002-06-21 CN CNA028165020A patent/CN1547463A/zh active Pending
-
2003
- 2003-12-15 IL IL159374A patent/IL159374A/en unknown
- 2003-12-17 NO NO20035653A patent/NO20035653L/no not_active Application Discontinuation
-
2004
- 2004-01-21 ZA ZA2004/00453A patent/ZA200400453B/en unknown
-
2006
- 2006-12-11 US US11/636,743 patent/US20070087058A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60203800T2 (de) | 2006-03-02 |
MXPA04000019A (es) | 2004-05-21 |
WO2003000230A1 (en) | 2003-01-03 |
US7163688B2 (en) | 2007-01-16 |
US20070087058A1 (en) | 2007-04-19 |
ES2243738T3 (es) | 2005-12-01 |
ZA200400453B (en) | 2005-05-25 |
EP1401395B1 (en) | 2005-04-20 |
NZ530260A (en) | 2006-11-30 |
PL364459A1 (en) | 2004-12-13 |
CA2451327C (en) | 2010-09-14 |
JP2004536640A (ja) | 2004-12-09 |
NO20035653D0 (no) | 2003-12-17 |
IL159374A0 (en) | 2004-06-01 |
AU2002315374B2 (en) | 2008-07-24 |
CA2451327A1 (en) | 2003-01-03 |
NO20035653L (no) | 2004-02-19 |
HUP0400334A3 (en) | 2008-03-28 |
EP1401395A1 (en) | 2004-03-31 |
RU2295359C2 (ru) | 2007-03-20 |
CN1547463A (zh) | 2004-11-17 |
HUP0400334A2 (hu) | 2004-08-30 |
DE60203800D1 (de) | 2005-05-25 |
US20030108590A1 (en) | 2003-06-12 |
RU2003136753A (ru) | 2005-03-27 |
ATE293436T1 (de) | 2005-05-15 |
IL159374A (en) | 2008-08-07 |
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Legal Events
Date | Code | Title | Description |
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B25A | Requested transfer of rights approved |
Free format text: JOHNSON & JOHNSON (US) |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2099 DE 29/03/2011. |