BR0210602A - Implante osmótico com membrana e recurso de retenção da membrana - Google Patents

Implante osmótico com membrana e recurso de retenção da membrana

Info

Publication number
BR0210602A
BR0210602A BR0210602-7A BR0210602A BR0210602A BR 0210602 A BR0210602 A BR 0210602A BR 0210602 A BR0210602 A BR 0210602A BR 0210602 A BR0210602 A BR 0210602A
Authority
BR
Brazil
Prior art keywords
membrane
capsule
osmotic
membrane material
retention feature
Prior art date
Application number
BR0210602-7A
Other languages
English (en)
Inventor
Gilbert J Scott
John R Peery
James E Brown
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BR0210602A publication Critical patent/BR0210602A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

"IMPLANTE OSMóTICO COM MEMBRANA E RECURSO DE RETENçãO DA MEMBRANA". Um sistema de liberação osmótico para a liberação controlada de um agente benéfico inclui uma cápsula que pode ser implantada contendo um agente benéfico e um mecanismo osmótico que dilata no contato com água, para dessa maneira causar a liberação do agente benéfico com o tempo. O sistema de liberação osmótico tem um material de membrana que permite que uma quantidade controlada de fluido entre do exterior da cápsula, enquanto evitando que as composições dentro da cápsula saiam da cápsula. O sistema de liberação osmótico é projetado para alcançar pelo menos as pressões de operação de 6875 Kpa (1000 psi), o material da membrana é fundido, calandrado ou extrudado seguido pela usinagem (isto é, corte em matriz, estampagem ou de outra maneira corte na forma) para produzir um material de membrana uniforme sem nervuras. A cápsula também inclui um recurso de retenção do material de membrana que é posicionado em uma extremidade de absorção do fluido para manter o material da membrana dentro da cápsula, mesmo sob períodos de alta pressão.
BR0210602-7A 2001-06-22 2002-06-21 Implante osmótico com membrana e recurso de retenção da membrana BR0210602A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30057501P 2001-06-22 2001-06-22
PCT/US2002/019531 WO2003000230A1 (en) 2001-06-22 2002-06-21 Osmotic implant with membrane and membrane retention means

Publications (1)

Publication Number Publication Date
BR0210602A true BR0210602A (pt) 2004-09-28

Family

ID=23159679

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0210602-7A BR0210602A (pt) 2001-06-22 2002-06-21 Implante osmótico com membrana e recurso de retenção da membrana

Country Status (19)

Country Link
US (2) US7163688B2 (pt)
EP (1) EP1401395B1 (pt)
JP (1) JP2004536640A (pt)
CN (1) CN1547463A (pt)
AT (1) ATE293436T1 (pt)
AU (1) AU2002315374B2 (pt)
BR (1) BR0210602A (pt)
CA (1) CA2451327C (pt)
DE (1) DE60203800T2 (pt)
ES (1) ES2243738T3 (pt)
HU (1) HUP0400334A3 (pt)
IL (2) IL159374A0 (pt)
MX (1) MXPA04000019A (pt)
NO (1) NO20035653L (pt)
NZ (1) NZ530260A (pt)
PL (1) PL364459A1 (pt)
RU (1) RU2295359C2 (pt)
WO (1) WO2003000230A1 (pt)
ZA (1) ZA200400453B (pt)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
US7258869B1 (en) 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
JP2005533782A (ja) * 2002-06-17 2005-11-10 アルザ コーポレイション 流体ビヒクル中に分散した浸透剤を含む、押出し力が早く零次になる機関を有する浸透送出システム
US20040224903A1 (en) * 2002-12-19 2004-11-11 Stephen Berry Stable, non-aqueous, single-phase gels and formulations thereof for delivery from an implantable device
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
CA2520766A1 (en) * 2003-03-31 2004-10-21 Alza Corporation Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems
JP2006521897A (ja) * 2003-03-31 2006-09-28 アルザ・コーポレーション 内部圧力を放散する手段を備える浸透ポンプ
KR20060076318A (ko) * 2003-09-26 2006-07-04 알자 코포레이션 밴딩 엔진을 포함하는 개선된 방출제어용 제형
SE526959C2 (sv) * 2003-10-02 2005-11-29 Tikomed Ab Bioartificellt implantat innefattande en semipermeabel barriär samt förfarande för reducering av risken för bildning av bindrväv vid implantatet efter implantering genom att barriären förses med en permeabel beläggning av bioaktiv metall
CA2545027A1 (en) * 2003-11-06 2005-05-26 Alza Corporation Modular imbibition rate reducer for use with implantable osmotic pump
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US7655254B2 (en) * 2005-02-03 2010-02-02 Intarcia Therapeutics, Inc. Implantable device for continuous delivery of interferon
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US7959938B2 (en) 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
US20080312587A1 (en) * 2005-06-10 2008-12-18 Gruenethal Gmbh System for the Oral Administration of Solids to Persons Suffering from Dementia
EP2020990B1 (en) 2006-05-30 2010-09-22 Intarcia Therapeutics, Inc Two-piece, internal-channel osmotic delivery system flow modulator
JP2009543902A (ja) 2006-07-10 2009-12-10 メディパックス インコーポレイテッド 超弾性エポキシヒドロゲル
AU2007284759B2 (en) 2006-08-09 2010-10-28 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
AU2008244523B2 (en) 2007-04-23 2012-02-16 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
US20130079749A1 (en) * 2007-08-29 2013-03-28 Advanced Bionics, Llc Modular Drug Delivery System for Minimizing Trauma During and After Insertion of a Cochlear Lead
JP2011505520A (ja) 2007-12-03 2011-02-24 メディパックス インコーポレイテッド 流体計量供給装置
EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
CN102281865B (zh) * 2008-10-15 2017-04-05 精达制药公司 高浓缩药物颗粒、制剂、混悬剂及其应用
CN102215901B (zh) * 2008-11-07 2014-12-03 联合生物医学系统有限公司 用于治疗和/或预防疾病的装置和方法
WO2011032011A1 (en) 2009-09-10 2011-03-17 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
EP2632730B1 (en) 2010-10-27 2019-08-07 Matthews International Corporation Valve jet printer with inert plunger tip
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
EP2847249A4 (en) 2012-03-14 2016-12-28 Medipacs Inc SMART POLYMER MATERIALS WITH EXCESSIVE REACTIVE MOLECULES
US20140147566A1 (en) 2012-11-28 2014-05-29 Quirky, Inc. Egg yolk separation apparatus and methods
CN104001261A (zh) * 2013-02-27 2014-08-27 重庆市北碚区精神卫生中心 一种皮下给药装置
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
EP3302354B1 (en) 2015-06-03 2023-10-04 i2o Therapeutics, Inc. Implant placement systems
EP3370705B1 (en) 2015-11-05 2022-03-09 The General Hospital Corporation Intrathecal delivery of nucleic acid sequences encoding abcd1 for treatment of adrenomyeloneuropathy
RU2760007C2 (ru) 2016-05-16 2021-11-22 Интарсия Терапьютикс, Инк. Полипептиды, селективные к рецепторам глюкагона, и способы их применения
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
MX2019004476A (es) 2016-10-20 2019-09-23 Peptron Inc Metodos para administrar un polipeptido neuroprotector al sistema nervioso central.
WO2018129058A1 (en) 2017-01-03 2018-07-12 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug
WO2018165462A1 (en) 2017-03-08 2018-09-13 Intarcia Therapeutics, Inc Apparatus and methods for administration of a nauseogenic compound from a drug delivery device
CN107970522A (zh) * 2017-11-24 2018-05-01 黑龙江工程学院 一种可降解金属基皮下载药埋置物及其制备方法
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
AU2019357621A1 (en) 2018-10-11 2021-05-27 Intarcia Therapeutics, Inc. Human amylin analog polypeptides and methods of use
CN112618094B (zh) * 2020-12-15 2021-12-10 上海澎立生技医药研究有限公司 一种脑梗的颈静脉插管给药装置

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3987790A (en) * 1975-10-01 1976-10-26 Alza Corporation Osmotically driven fluid dispenser
US4865845A (en) * 1986-03-21 1989-09-12 Alza Corporation Release rate adjustment of osmotic or diffusional delivery devices
US5059423A (en) * 1988-12-13 1991-10-22 Alza Corporation Delivery system comprising biocompatible beneficial agent formulation
US5112614A (en) * 1989-09-14 1992-05-12 Alza Corporation Implantable delivery dispenser
US5213809A (en) * 1990-01-24 1993-05-25 Alza Corporation Delivery system comprising means for controlling internal pressure
US5324280A (en) * 1990-04-02 1994-06-28 Alza Corporation Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
US5234693A (en) 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5234692A (en) * 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5137727A (en) * 1991-06-12 1992-08-11 Alza Corporation Delivery device providing beneficial agent stability
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5324693A (en) * 1992-10-13 1994-06-28 Mitsubishi Materials Corporation Ceramic composites and process for manufacturing the same
US5540665A (en) * 1994-01-31 1996-07-30 Alza Corporation Gas driven dispensing device and gas generating engine therefor
JP4176832B2 (ja) * 1996-02-02 2008-11-05 インターシア セラピューティクス， インコーポレイティド 移植可能な系を用いる活性剤の持続投与
ZA981610B (en) * 1997-03-24 1999-08-26 Alza Corp Self adjustable exit port.
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
MY125849A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
WO1999033446A1 (en) 1997-12-29 1999-07-08 Alza Corporation Osmotic delivery system with membrane plug retention mechanism
ES2378675T3 (es) * 1997-12-30 2012-04-16 Intarcia Therapeutics, Inc Sistema de suministro de un agente beneficioso con una membrana obturadora
DE69906132T2 (de) * 1998-12-31 2003-12-18 Alza Corp Osmotisches verabreichungsystem mit raumsparenden kolben
JP2005533782A (ja) * 2002-06-17 2005-11-10 アルザ コーポレイション 流体ビヒクル中に分散した浸透剤を含む、押出し力が早く零次になる機関を有する浸透送出システム
US7014636B2 (en) * 2002-11-21 2006-03-21 Alza Corporation Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
CA2545027A1 (en) * 2003-11-06 2005-05-26 Alza Corporation Modular imbibition rate reducer for use with implantable osmotic pump

Also Published As

Publication number Publication date
IL159374A (en) 2008-08-07
EP1401395B1 (en) 2005-04-20
EP1401395A1 (en) 2004-03-31
DE60203800T2 (de) 2006-03-02
ZA200400453B (en) 2005-05-25
RU2295359C2 (ru) 2007-03-20
US20030108590A1 (en) 2003-06-12
US20070087058A1 (en) 2007-04-19
CN1547463A (zh) 2004-11-17
ATE293436T1 (de) 2005-05-15
DE60203800D1 (de) 2005-05-25
NZ530260A (en) 2006-11-30
RU2003136753A (ru) 2005-03-27
NO20035653D0 (no) 2003-12-17
ES2243738T3 (es) 2005-12-01
CA2451327C (en) 2010-09-14
CA2451327A1 (en) 2003-01-03
AU2002315374B2 (en) 2008-07-24
WO2003000230A1 (en) 2003-01-03
US7163688B2 (en) 2007-01-16
HUP0400334A2 (hu) 2004-08-30
NO20035653L (no) 2004-02-19
HUP0400334A3 (en) 2008-03-28
PL364459A1 (en) 2004-12-13
IL159374A0 (en) 2004-06-01
MXPA04000019A (es) 2004-05-21
JP2004536640A (ja) 2004-12-09

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Free format text: JOHNSON & JOHNSON (US)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2099 DE 29/03/2011.