BR0208940A - Composto diazepìnico tricìclico, composição farmacêutica compreendendo o mesmo e seu uso - Google Patents

Composto diazepìnico tricìclico, composição farmacêutica compreendendo o mesmo e seu uso

Info

Publication number
BR0208940A
BR0208940A BR0208940-8A BR0208940A BR0208940A BR 0208940 A BR0208940 A BR 0208940A BR 0208940 A BR0208940 A BR 0208940A BR 0208940 A BR0208940 A BR 0208940A
Authority
BR
Brazil
Prior art keywords
disorders
treating
compounds
tricyclic diazepine
oxytocin
Prior art date
Application number
BR0208940-8A
Other languages
English (en)
Inventor
Amedeo Arturo Failli
William Jennings Sanders
Eugene John Trybulski
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BR0208940A publication Critical patent/BR0208940A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMPOSTO DIAZEPìNICO TRICìCLICO, COMPOSIçãO FARMACêUTICA COMPREENDENDO O MESMO E SEU USO". A presente invenção prove compostos diazepínicos tricíclicos novos e métodos e composições farmacêuticas utilizando os mesmos para o tratamento ou prevenção de distúrbios, incluindo diabete insípido, enurese noturna, noctúria, incontinência urinária, distúrbios de sangramento e coagulação, insuficiência coronária congestiva, ou para induzir atraso temporário de urinação, e em condições com resistência vascular aumentada e vasoconstrição coronária; e para o tratamento e prevenção de distúrbios remediados ou aliviados por atividade de antagonista de oxitocina, incluindo supressão de parto prematuro, dismenorréia, endometrite, e para impedir parto antes do parto cesariano. Estes compostos são também úteis para aumentar as taxas de fertilidade, taxas de sobrevivência e sincronizar o estro em gado de curral; e para tratamento de disfunção do sistema de oxitocina no sistema nervoso central, incluindo transtorno obsessivo-compulsivo (TOC ) e transtornos neuropsiquiátricos.
BR0208940-8A 2001-04-12 2002-04-11 Composto diazepìnico tricìclico, composição farmacêutica compreendendo o mesmo e seu uso BR0208940A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28326501P 2001-04-12 2001-04-12
PCT/US2002/011531 WO2002083681A1 (en) 2001-04-12 2002-04-11 Novel cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators

Publications (1)

Publication Number Publication Date
BR0208940A true BR0208940A (pt) 2004-04-27

Family

ID=23085256

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0208940-8A BR0208940A (pt) 2001-04-12 2002-04-11 Composto diazepìnico tricìclico, composição farmacêutica compreendendo o mesmo e seu uso

Country Status (12)

Country Link
US (1) US7022699B2 (pt)
EP (1) EP1377584B1 (pt)
JP (1) JP2004530671A (pt)
CN (1) CN1501935A (pt)
AT (1) ATE289309T1 (pt)
BR (1) BR0208940A (pt)
CA (1) CA2443565A1 (pt)
DE (1) DE60203000T2 (pt)
DK (1) DK1377584T3 (pt)
ES (1) ES2236511T3 (pt)
MX (1) MXPA03009335A (pt)
WO (1) WO2002083681A1 (pt)

Families Citing this family (30)

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US6977254B2 (en) 2001-04-12 2005-12-20 Wyeth Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US6900200B2 (en) * 2001-04-12 2005-05-31 Wyeth Tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
US7109193B2 (en) * 2001-04-12 2006-09-19 Wyeth Tricyclic diazepines tocolytic oxytocin receptor antagonists
US7202239B2 (en) * 2001-04-12 2007-04-10 Wyeth Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists
US7326700B2 (en) * 2001-04-12 2008-02-05 Wyeth Cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US6903087B2 (en) 2001-04-12 2005-06-07 Wyeth Pyrido cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7064120B2 (en) * 2001-04-12 2006-06-20 Wyeth Tricyclic pyridyl carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
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AU2016429272A1 (en) 2016-11-14 2019-05-02 Hangzhou Dac Biotech Co., Ltd. Conjugation linkers, cell binding molecule-drug conjugates containing the likers, methods of making and uses such conjugates with the linkers

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US7202239B2 (en) * 2001-04-12 2007-04-10 Wyeth Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists
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Also Published As

Publication number Publication date
ES2236511T3 (es) 2005-07-16
US20020198196A1 (en) 2002-12-26
CA2443565A1 (en) 2002-10-24
EP1377584A1 (en) 2004-01-07
WO2002083681A1 (en) 2002-10-24
MXPA03009335A (es) 2005-10-05
DE60203000D1 (de) 2005-03-24
JP2004530671A (ja) 2004-10-07
DK1377584T3 (da) 2005-05-23
EP1377584B1 (en) 2005-02-16
CN1501935A (zh) 2004-06-02
US7022699B2 (en) 2006-04-04
ATE289309T1 (de) 2005-03-15
DE60203000T2 (de) 2006-03-23

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009.