BR0206371A - Composição farmacêutica sólida solúvel em água não efervescente, composição farmacêutica lìquida oral, e, processo para a fabricação de uma composição granulada - Google Patents

Composição farmacêutica sólida solúvel em água não efervescente, composição farmacêutica lìquida oral, e, processo para a fabricação de uma composição granulada

Info

Publication number
BR0206371A
BR0206371A BR0206371-9A BR0206371A BR0206371A BR 0206371 A BR0206371 A BR 0206371A BR 0206371 A BR0206371 A BR 0206371A BR 0206371 A BR0206371 A BR 0206371A
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
composition
manufacture
oral liquid
solid soluble
Prior art date
Application number
BR0206371-9A
Other languages
English (en)
Inventor
Alberto Reiner
Giorgio Reiner
Original Assignee
Apr Applied Pharma Res Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apr Applied Pharma Res Sa filed Critical Apr Applied Pharma Res Sa
Publication of BR0206371A publication Critical patent/BR0206371A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA SóLIDA SOLúVEL EM áGUA NãO EFERVESCENTE, COMPOSIçãO FARMACêUTICA LìQUIDA ORAL, E, PROCESSO PARA A FABRICAçãO DE UMA COMPOSIçãO GRANULADA". São descritas composições farmacêuticas não efervescentes solúveis em água compreendendo um sal solúvel em água de um NSAID tendo uma estrutura aril- propiónica ou arilacética e uma mistura de pelo menos dois ácidos orgânicos di- ou tri-carboxílicos farmaceuticamente aceitáveis completamente salinizados, em quantidades e proporções para mascarar o gosto do sal de NSAID em solução aquosa. De acordo com a invenção atual, as composições, mesmo sem sabor, fornecem soluções aquosas perfeitamente potáveis, que depois da ingestão, não provocam a sensação desagradavelmente irritante, típica da formulação conhecida.
BR0206371-9A 2001-11-20 2002-11-19 Composição farmacêutica sólida solúvel em água não efervescente, composição farmacêutica lìquida oral, e, processo para a fabricação de uma composição granulada BR0206371A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01204432A EP1312355B1 (en) 2001-11-20 2001-11-20 Water-soluble non-effervescent pharmaceutical compositions comprising non-steroidal anti-inflammatory drugs
PCT/EP2002/012983 WO2003043600A1 (en) 2001-11-20 2002-11-19 Water-soluble non-effervescent pharmaceutical compositions comprising non-steroidal anti-inflammatory drugs

Publications (1)

Publication Number Publication Date
BR0206371A true BR0206371A (pt) 2003-12-23

Family

ID=8181265

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0206371-9A BR0206371A (pt) 2001-11-20 2002-11-19 Composição farmacêutica sólida solúvel em água não efervescente, composição farmacêutica lìquida oral, e, processo para a fabricação de uma composição granulada

Country Status (9)

Country Link
EP (1) EP1312355B1 (pt)
AT (1) ATE242626T1 (pt)
AU (1) AU2002356685A1 (pt)
BR (1) BR0206371A (pt)
DE (1) DE60100364T2 (pt)
DK (1) DK1312355T3 (pt)
ES (1) ES2199916T3 (pt)
PT (1) PT1312355E (pt)
WO (1) WO2003043600A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100567131B1 (ko) * 2004-01-05 2006-04-05 신일제약주식회사 쓴맛을 차폐한 아르기닌 함유 이부프로펜 경구투여 액상조성물
FR2865648B1 (fr) 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
US7776318B2 (en) 2004-11-26 2010-08-17 L'oreal S.A. Liquid cleaning composition comprising at least one anionic surfactant and its use for cleansing human keratin materials
JO3352B1 (ar) * 2005-06-17 2019-03-13 Apr Applied Pharma Res Sa صيغ دايكلوفيناك وطرق استخدامه
WO2013022410A2 (en) 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
EP3508199A1 (en) * 2018-01-05 2019-07-10 Dompé farmaceutici S.p.A. Immediate-release pharmaceutical compositions containing ketoprofen lysine salt
EP3893865A1 (en) 2018-12-14 2021-10-20 Apr Applied Pharma Research S.A. Ready to use diclofenac stick packs
KR20230022941A (ko) 2020-06-10 2023-02-16 에이피알 어플라이드 파르마 리서어치 에스.에이. 생체이용성 당-기반 디클로페낙 제형

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8920693D0 (en) * 1989-09-13 1989-10-25 Nicholas Kiwi Pty Ltd Non-effervescent ibuprofen compositions
DE4403943A1 (de) * 1994-02-08 1995-08-10 Hexal Pharma Gmbh Orale Azrneimittelzubereitung mit Diclofenac-Natrium
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat

Also Published As

Publication number Publication date
ES2199916T3 (es) 2004-03-01
AU2002356685A1 (en) 2003-06-10
EP1312355A1 (en) 2003-05-21
DE60100364T2 (de) 2003-12-04
PT1312355E (pt) 2003-10-31
ATE242626T1 (de) 2003-06-15
DE60100364D1 (de) 2003-07-31
EP1312355B1 (en) 2003-06-11
DK1312355T3 (da) 2003-10-06
WO2003043600A1 (en) 2003-05-30

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI: A61K 9/16, A61K 9/14, A61K 9/00, A61P 29/00

Ipc: A61K 9/16 (2006.01), A61K 9/14 (2006.01), A61K 9/0

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.