BR0116841A - Etanolatos de inibidor de permutador sódio-hidrogênio do tipo-1 - Google Patents

Etanolatos de inibidor de permutador sódio-hidrogênio do tipo-1

Info

Publication number
BR0116841A
BR0116841A BR0116841-0A BR0116841A BR0116841A BR 0116841 A BR0116841 A BR 0116841A BR 0116841 A BR0116841 A BR 0116841A BR 0116841 A BR0116841 A BR 0116841A
Authority
BR
Brazil
Prior art keywords
ethanolates
type
sodium hydrogen
ethanolate
hydrogen exchanger
Prior art date
Application number
BR0116841-0A
Other languages
English (en)
Inventor
Timothy Norris
Rodley Matthew Weekly
Original Assignee
Pfizer Producs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Producs Inc filed Critical Pfizer Producs Inc
Publication of BR0116841A publication Critical patent/BR0116841A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"ETANOLATOS DE INIBIDOR DE PERMUTADOR SóDIO-HIDROGêNIO DO TIPO-1". Esta invenção refere-se a etanolatos do inibidor de NHE-1, N-(5-ciclopropil-1-quinolin-5-il-1H-pirazol-4-carbonil)-guanidina, formas cristalinas dos etanolatos, métodos de preparação dos etanolatos, métodos de tratamento utilizando os etanolatos e o sal de mesilato do inibidor de NHE-1 preparado, utilizando os etanolatos.
BR0116841-0A 2001-01-31 2001-12-21 Etanolatos de inibidor de permutador sódio-hidrogênio do tipo-1 BR0116841A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26545601P 2001-01-31 2001-01-31
PCT/IB2001/002652 WO2002060892A1 (en) 2001-01-31 2001-12-21 Ethanolates of sodium-hydrogen exchanger type-1 inhibitor

Publications (1)

Publication Number Publication Date
BR0116841A true BR0116841A (pt) 2004-02-25

Family

ID=23010519

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0116841-0A BR0116841A (pt) 2001-01-31 2001-12-21 Etanolatos de inibidor de permutador sódio-hidrogênio do tipo-1

Country Status (17)

Country Link
US (1) US20020147218A1 (pt)
EP (1) EP1355899A1 (pt)
JP (1) JP2004518686A (pt)
KR (1) KR20030069228A (pt)
CN (1) CN1479737A (pt)
AR (1) AR035740A1 (pt)
BR (1) BR0116841A (pt)
CA (1) CA2436539A1 (pt)
CZ (1) CZ20032017A3 (pt)
HU (1) HUP0302860A2 (pt)
IL (1) IL156220A0 (pt)
MX (1) MXPA03006872A (pt)
PL (1) PL363472A1 (pt)
RU (1) RU2242472C1 (pt)
WO (1) WO2002060892A1 (pt)
YU (1) YU51903A (pt)
ZA (1) ZA200303891B (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100449600B1 (ko) * 1998-02-27 2004-09-21 화이자 프로덕츠 인크. 허혈 치료용 ｎ-[(치환된 5원 디아자 이불포화 고리)카르보닐] 구아니딘 유도체
US6441176B1 (en) * 1999-10-29 2002-08-27 Pfizer Inc. Method for preparing sodium-hydrogen exchanger type 1 inhibitor
UA72002C2 (en) * 1999-10-29 2005-01-17 Pfizer Prod Inc Inhibitors crystals of sodium-hydrogen exchange of 1 type, a method for the preparation thereof (variants), a pharmaceuticalcomposition based thereon and a method for the reduction of tissue damage
CA2407535A1 (en) * 2000-04-28 2001-11-08 Pfizer Products Inc. Sodium-hydrogen exchanger type 1 inhibitor (nhe-1)

Also Published As

Publication number Publication date
RU2003123792A (ru) 2005-01-20
AR035740A1 (es) 2004-07-07
IL156220A0 (en) 2003-12-23
CA2436539A1 (en) 2002-08-08
WO2002060892A8 (en) 2003-07-31
PL363472A1 (en) 2004-11-15
CN1479737A (zh) 2004-03-03
CZ20032017A3 (cs) 2004-05-12
US20020147218A1 (en) 2002-10-10
YU51903A (sh) 2006-05-25
KR20030069228A (ko) 2003-08-25
RU2242472C1 (ru) 2004-12-20
HUP0302860A2 (hu) 2003-12-29
JP2004518686A (ja) 2004-06-24
EP1355899A1 (en) 2003-10-29
ZA200303891B (en) 2004-05-20
WO2002060892A1 (en) 2002-08-08
MXPA03006872A (es) 2003-11-13

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 1964 DE 26/08/2008 E CONSIDERANDO A AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS.