HUP0302860A2 - Nátrium-hidrogén cserélő 1-típusú inhibitor hatású vegyület új etanolátjai, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények - Google Patents

Nátrium-hidrogén cserélő 1-típusú inhibitor hatású vegyület új etanolátjai, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0302860A2
HUP0302860A2 HU0302860A HUP0302860A HUP0302860A2 HU P0302860 A2 HUP0302860 A2 HU P0302860A2 HU 0302860 A HU0302860 A HU 0302860A HU P0302860 A HUP0302860 A HU P0302860A HU P0302860 A2 HUP0302860 A2 HU P0302860A2
Authority
HU
Hungary
Prior art keywords
ethanolates
inhibitor
sodium
preparation
new
Prior art date
Application number
HU0302860A
Other languages
English (en)
Inventor
Timothy Norris
Rodney Matthew Weekly
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of HUP0302860A2 publication Critical patent/HUP0302860A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A találmány NHE-1 inhibitor hatású N-(5-ciklopropil-1-kinolin-5-il-1H-pirazol-4-karbonil)-guanidin-etanolát, -monoetanolát és -mezilátsójára, valamint ezek kristályos formáira, a vegyületek előállításieljárására, valamint a vegyületeket hatóanyagként tartalmazógyógyszerkészítményekre vonatkozik. Ó
HU0302860A 2001-01-31 2001-12-21 Nátrium-hidrogén cserélő 1-típusú inhibitor hatású vegyület új etanolátjai, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények HUP0302860A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26545601P 2001-01-31 2001-01-31
PCT/IB2001/002652 WO2002060892A1 (en) 2001-01-31 2001-12-21 Ethanolates of sodium-hydrogen exchanger type-1 inhibitor

Publications (1)

Publication Number Publication Date
HUP0302860A2 true HUP0302860A2 (hu) 2003-12-29

Family

ID=23010519

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302860A HUP0302860A2 (hu) 2001-01-31 2001-12-21 Nátrium-hidrogén cserélő 1-típusú inhibitor hatású vegyület új etanolátjai, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények

Country Status (17)

Country Link
US (1) US20020147218A1 (hu)
EP (1) EP1355899A1 (hu)
JP (1) JP2004518686A (hu)
KR (1) KR20030069228A (hu)
CN (1) CN1479737A (hu)
AR (1) AR035740A1 (hu)
BR (1) BR0116841A (hu)
CA (1) CA2436539A1 (hu)
CZ (1) CZ20032017A3 (hu)
HU (1) HUP0302860A2 (hu)
IL (1) IL156220A0 (hu)
MX (1) MXPA03006872A (hu)
PL (1) PL363472A1 (hu)
RU (1) RU2242472C1 (hu)
WO (1) WO2002060892A1 (hu)
YU (1) YU51903A (hu)
ZA (1) ZA200303891B (hu)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA003603B1 (ru) * 1998-02-27 2003-06-26 Пфайзер Продактс Инк. N-[(замещенное пятичленное ди- или триазадиненасыщенное кольцо) карбонил] гуанидиновые производные для лечения ишемии
UA72002C2 (en) * 1999-10-29 2005-01-17 Pfizer Prod Inc Inhibitors crystals of sodium-hydrogen exchange of 1 type, a method for the preparation thereof (variants), a pharmaceuticalcomposition based thereon and a method for the reduction of tissue damage
US6441176B1 (en) * 1999-10-29 2002-08-27 Pfizer Inc. Method for preparing sodium-hydrogen exchanger type 1 inhibitor
AP2002002651A0 (en) * 2000-04-28 2002-12-31 Pfizer Prod Inc Sodium-hydrogen exchanger type 1 inhibitor (nhe-1)

Also Published As

Publication number Publication date
EP1355899A1 (en) 2003-10-29
MXPA03006872A (es) 2003-11-13
BR0116841A (pt) 2004-02-25
KR20030069228A (ko) 2003-08-25
CN1479737A (zh) 2004-03-03
YU51903A (sh) 2006-05-25
PL363472A1 (en) 2004-11-15
CA2436539A1 (en) 2002-08-08
CZ20032017A3 (cs) 2004-05-12
US20020147218A1 (en) 2002-10-10
RU2242472C1 (ru) 2004-12-20
AR035740A1 (es) 2004-07-07
JP2004518686A (ja) 2004-06-24
IL156220A0 (en) 2003-12-23
WO2002060892A8 (en) 2003-07-31
RU2003123792A (ru) 2005-01-20
WO2002060892A1 (en) 2002-08-08
ZA200303891B (en) 2004-05-20

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees