BR0114036A - Peptìdeos de hiv, antìgenos, composições de vacina, kit de imunoensaio e um método para detectar anticorpos induzidos pelo hiv - Google Patents
Peptìdeos de hiv, antìgenos, composições de vacina, kit de imunoensaio e um método para detectar anticorpos induzidos pelo hivInfo
- Publication number
- BR0114036A BR0114036A BR0114036-1A BR0114036A BR0114036A BR 0114036 A BR0114036 A BR 0114036A BR 0114036 A BR0114036 A BR 0114036A BR 0114036 A BR0114036 A BR 0114036A
- Authority
- BR
- Brazil
- Prior art keywords
- hiv
- antigens
- peptides
- vaccine compositions
- induced antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- AIDS & HIV (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
"PEPTìDEOS DE HIV, ANTìGENOS, COMPOSIçõES DE VACINA, KIT DE IMUNOENSAIO E UM MéTODO PARA DETECTAR ANTICORPOS INDUZIDOS PELO HIV". A presente invenção compreende novos e modificados peptídeos capazes de induzir uma resposta imune específica do HIV-1 sem antagonizar a atividade da célula T citotóxica para alcançar uma vacina profilática e terapêutica eficaz contra o HIV. Os peptídeos baseiam-se nas regiões conservadas de proteínas do HIV gag p17 e p24. Os antígenos na forma livre ou ligada a portador compreendendo pelo menos um dos referidos peptídeos, composições de vacina contendo pelo menos um dos antígenos, kits de imunoensaios e um método para detectar anticorpos, induzidos por HIV ou peptídeos específicos do HIV, usando tais antígenos, são descritos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20004413A NO314588B1 (no) | 2000-09-04 | 2000-09-04 | HIV-peptider, antigener, vaksinesammensetning, immunoassay- testsett og en fremgangsmåte for å påvise antistoffer indusert av HIV |
| PCT/NO2001/000362 WO2002020554A2 (en) | 2000-09-04 | 2001-09-03 | Hiv peptides from conserved regions in gag p17 and 924 and their application in e.g. vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0114036A true BR0114036A (pt) | 2003-07-22 |
Family
ID=19911533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0114036-1A BR0114036A (pt) | 2000-09-04 | 2001-09-03 | Peptìdeos de hiv, antìgenos, composições de vacina, kit de imunoensaio e um método para detectar anticorpos induzidos pelo hiv |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7009037B2 (pt) |
| EP (2) | EP1322665B1 (pt) |
| JP (2) | JP2004508381A (pt) |
| CN (2) | CN1282656C (pt) |
| AR (2) | AR033998A1 (pt) |
| AT (1) | ATE406380T1 (pt) |
| AU (3) | AU2001282706B2 (pt) |
| BR (1) | BR0114036A (pt) |
| CA (1) | CA2421193A1 (pt) |
| DE (1) | DE60135564D1 (pt) |
| EA (1) | EA006308B1 (pt) |
| ES (1) | ES2312465T3 (pt) |
| HK (1) | HK1059940A1 (pt) |
| HU (1) | HUP0303134A3 (pt) |
| MY (1) | MY136081A (pt) |
| NO (1) | NO314588B1 (pt) |
| NZ (2) | NZ524556A (pt) |
| SK (1) | SK287917B6 (pt) |
| WO (1) | WO2002020554A2 (pt) |
| ZA (1) | ZA200301740B (pt) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0108210A (pt) | 2000-02-04 | 2002-10-22 | Univ Duke | Vacina contra o vìrus da imunodeficiência humana |
| EP2045282B1 (en) * | 2005-08-26 | 2011-03-23 | Novo Nordisk A/S | A method of modifying a macromolecular system |
| FI120376B (fi) * | 2007-01-17 | 2009-09-30 | Next Biomed Technologies Nbt O | Menetelmä biomuokatun, korkean affiniteetin polypeptidin valmistamiseksi |
| FI120349B (fi) | 2007-03-07 | 2009-09-30 | Next Biomed Technologies Nbt O | Menetelmä fuusiopolypeptidin valmistamiseksi |
| AP2857A (en) | 2008-09-09 | 2014-02-28 | Celebrity Biogens Llc | Bioactive composition for the treatment of the HIV/AIDS, method for manufacturing and using the same |
| WO2010045659A1 (en) | 2008-10-17 | 2010-04-22 | American Gene Technologies International Inc. | Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules |
| US9733242B2 (en) | 2012-10-07 | 2017-08-15 | Sevident, Inc. | Devices for capturing analyte |
| US9910040B2 (en) | 2012-07-09 | 2018-03-06 | Sevident, Inc. | Molecular nets comprising capture agents and linking agents |
| FR2957933B1 (fr) * | 2010-03-24 | 2012-04-27 | Seppic Sa | Vaccin vivant pour maladies aviaires |
| CA2793959C (en) | 2010-03-25 | 2019-06-04 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| EP3338798A1 (en) * | 2011-01-06 | 2018-06-27 | Bionor Immuno AS | Multimeric peptide |
| CA2832109C (en) | 2011-06-10 | 2021-07-06 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| AU2012216792A1 (en) | 2011-09-12 | 2013-03-28 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies |
| EP2586461A1 (en) | 2011-10-27 | 2013-05-01 | Christopher L. Parks | Viral particles derived from an enveloped virus |
| WO2013182661A1 (en) | 2012-06-06 | 2013-12-12 | Bionor Immuno As | Peptides derived from viral proteins for use as immunogens and dosage reactants |
| EP2679596B1 (en) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | HIV-1 env glycoprotein variant |
| EP2976325B1 (en) | 2013-03-21 | 2017-03-01 | Sanofi-Aventis Deutschland GmbH | Synthesis of cyclic imide containing peptide products |
| CA2907454C (en) | 2013-03-21 | 2021-05-04 | Sanofi-Aventis Deutschland Gmbh | Synthesis of hydantoin containing peptide products |
| US20150065381A1 (en) | 2013-09-05 | 2015-03-05 | International Aids Vaccine Initiative | Methods of identifying novel hiv-1 immunogens |
| EP2873423B1 (en) | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US10174292B2 (en) | 2015-03-20 | 2019-01-08 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| WO2017007994A1 (en) | 2015-07-08 | 2017-01-12 | American Gene Technologies International Inc. | Hiv pre-immunization and immunotherapy |
| CN111569090A (zh) | 2016-01-15 | 2020-08-25 | 美国基因技术国际有限公司 | 用于活化γ-δ T细胞的方法和组合物 |
| US10137144B2 (en) | 2016-01-15 | 2018-11-27 | American Gene Technologies International Inc. | Methods and compositions for the activation of gamma-delta T-cells |
| JP7153332B2 (ja) | 2016-02-08 | 2022-10-14 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | Ｈｉｖワクチン接種および免疫療法 |
| JP7017247B2 (ja) | 2016-03-09 | 2022-02-08 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | がんを処置するための組み合わせベクターおよび方法 |
| WO2017213697A1 (en) | 2016-06-08 | 2017-12-14 | American Gene Technologies International Inc. | Non-integrating viral delivery system and methods related thereto |
| JP6971492B2 (ja) | 2016-07-08 | 2021-11-24 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | Ｈｉｖ予備免疫化および免疫療法 |
| JP7176756B2 (ja) | 2016-07-21 | 2022-11-22 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | パーキンソン病を処置するためのウイルスベクター |
| EP3607072A4 (en) | 2017-04-03 | 2021-01-06 | American Gene Technologies International Inc. | COMPOSITIONS AND METHODS OF TREATMENT OF PHENYLCETONURISM |
| US11352646B2 (en) | 2018-11-05 | 2022-06-07 | American Gene Technologies International Inc. | Vector system for expressing regulatory RNA |
| RU2727673C1 (ru) * | 2019-08-09 | 2020-07-22 | Федеральное государственное унитарное предприятие «Государственный научно-исследовательский институт особо чистых биопрепаратов» Федерального медико-биологического агентства | Антитела против белка р17 ВИЧ-1 субтипа А |
| GB2610556A (en) * | 2021-09-02 | 2023-03-15 | 113 Botanicals Ltd | Extraction |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ235538A (en) * | 1989-10-12 | 1992-06-25 | Viral Technologies Inc | Peptides immunoreactive with antibodies to hiv p17; carrier-bound peptides, vaccines, immunoassay and a method for forming antibody enriched sera |
| SE468168B (sv) | 1990-02-20 | 1992-11-16 | Replico Medical Ab | Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov |
| DE4039925A1 (de) * | 1990-12-14 | 1992-06-17 | Behringwerke Ag | Ausgewaehlte peptide des gruppenspezifischen antigens (gag) von humanem immundefizienzvirus (hiv), ihre herstellung und verwendung |
| SE9101863D0 (sv) * | 1991-06-13 | 1991-06-13 | Replico Medical Ab | Peptider, diagnostiskt antigen, vaccinkomposition och foerfarande foer selektering av hiv-stammar |
| EP0907740A1 (en) | 1997-01-02 | 1999-04-14 | Universidade Federal De Minas Gerais | THE PROCESS FOR EXPRESSION AND PRODUCTION OF RECOMBINANT PROTEIN HYBRID PROTEIN (p24/p17) DERIVED FROM HUMAN IMMUNODEFICIENCY VIRUSES (HIV-1) |
| GB9703802D0 (en) * | 1997-02-24 | 1997-04-16 | Kingsman Susan M | Anti-hiv peptides and proteins |
| US5972339A (en) | 1997-11-13 | 1999-10-26 | The General Hospital Corporation | Method of eliciting anti-HIV-1 helper T cell responses |
| EP1078092B1 (en) | 1998-05-13 | 2011-08-03 | Epimmune Inc. | Expression vectors for stimulating an immune response and methods of using the same |
| NO311807B1 (no) * | 1999-03-04 | 2002-01-28 | Bionor Immuno As | HIV-peptider, antigener, vaksinepreparater, immunoassay- testsett og en metode for påvisning av antistoffer fremkalt av HIV |
-
2000
- 2000-09-04 NO NO20004413A patent/NO314588B1/no not_active IP Right Cessation
-
2001
- 2001-09-03 NZ NZ524556A patent/NZ524556A/en not_active IP Right Cessation
- 2001-09-03 ZA ZA200301740A patent/ZA200301740B/en unknown
- 2001-09-03 WO PCT/NO2001/000362 patent/WO2002020554A2/en active IP Right Grant
- 2001-09-03 AU AU2001282706A patent/AU2001282706B2/en not_active Ceased
- 2001-09-03 AT AT01961444T patent/ATE406380T1/de not_active IP Right Cessation
- 2001-09-03 AU AU8270601A patent/AU8270601A/xx active Pending
- 2001-09-03 EP EP01961444A patent/EP1322665B1/en not_active Expired - Lifetime
- 2001-09-03 CN CNB018157424A patent/CN1282656C/zh not_active Expired - Fee Related
- 2001-09-03 EP EP07014954A patent/EP1878742A3/en not_active Withdrawn
- 2001-09-03 HU HU0303134A patent/HUP0303134A3/hu unknown
- 2001-09-03 ES ES01961444T patent/ES2312465T3/es not_active Expired - Lifetime
- 2001-09-03 DE DE60135564T patent/DE60135564D1/de not_active Expired - Lifetime
- 2001-09-03 JP JP2002525174A patent/JP2004508381A/ja active Pending
- 2001-09-03 CN CNA2006101517487A patent/CN101104636A/zh active Pending
- 2001-09-03 CA CA002421193A patent/CA2421193A1/en not_active Abandoned
- 2001-09-03 NZ NZ535148A patent/NZ535148A/en not_active IP Right Cessation
- 2001-09-03 SK SK402-2003A patent/SK287917B6/sk not_active IP Right Cessation
- 2001-09-03 US US10/129,331 patent/US7009037B2/en not_active Expired - Fee Related
- 2001-09-03 BR BR0114036-1A patent/BR0114036A/pt not_active IP Right Cessation
- 2001-09-03 EA EA200300336A patent/EA006308B1/ru not_active IP Right Cessation
- 2001-09-04 MY MYPI20014139A patent/MY136081A/en unknown
- 2001-09-04 AR ARP010104196A patent/AR033998A1/es active IP Right Grant
-
2004
- 2004-04-22 HK HK04102846A patent/HK1059940A1/xx not_active IP Right Cessation
-
2005
- 2005-08-26 US US11/211,576 patent/US7612168B2/en not_active Expired - Fee Related
-
2007
- 2007-06-13 AU AU2007202739A patent/AU2007202739B2/en not_active Ceased
-
2008
- 2008-12-03 AR ARP080105262A patent/AR071262A2/es not_active Application Discontinuation
-
2011
- 2011-06-08 JP JP2011128389A patent/JP2011219481A/ja active Pending
Also Published As
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| FR2874017B1 (fr) | Peptides vih-1 modifies et leur utilisation en detection d'anticorps anti-vih | |
| Lambert et al. | Antibody to human immunodeficiency virus type 1 (HIV-1) gp160 in mucosal specimens of asymptomatic HIV-1-infected volunteers parenterally immunized with an experimental recombinant HIV-1 IIIB gp160 vaccine. The National Institute of Allergy and Infectious Diseases-sponsored AIDS Vaccine Evaluation Group | |
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